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The map label for this gene is modD [H]

Identifier: 218704714

GI number: 218704714

Start: 1495170

End: 1496024

Strand: Reverse

Name: modD [H]

Synonym: ECUMN_1488

Alternate gene names: 218704714

Gene position: 1496024-1495170 (Counterclockwise)

Preceding gene: 218704715

Following gene: 218704713

Centisome position: 28.76

GC content: 51.93

Gene sequence:

>855_bases
ATGATTTTCCTTTCTCAGGCACAAATCGATGCGTTACTTCTGGAAGATATCCAGGGCGGTGACCTGACCACGCGAGCATT
AAATATTGGACACCAGCATGGCTATATAGAGTTTTTTCACCGTCAGGGCGGCTGCGTCAGCGGCGTTTCTGTCGCGTGTA
AGATGTTAACTACGCTGGGATTAACTATTGATGACGCGGTCAGCGACGGTTCACAAGCGAACGCGGGTCAGCGGCTAATC
CGTGCGCAGGGTAATGCCGCAGCACTTCATCAGGGATGGAAGGCAGTCCAGAATGTGCTGGAGTGGAGTTGCGGTGTTTC
TGATTATCTCACTCAAATGCTGGCGTTACTTCGTGAACGTTACCCTGATGGCAATATCGCCTGCACCCGAAAAGCAATTC
CGGGCACCCGCTTACTGGCCTCGCAGGCAATTCTGACTGCCGGAGGACTGATTCATCGTGCCGGATGTGCGGAAACCATA
TTATTGTTTGCCAACCACCGTCATTTTCTTCATGACAATCAGGACTGGTCAGGCGCAATCAATCAGTTACGTCGCCACGC
ACCCGAGAAGAAAATAGTTGTTGAAGCCGACACGCCGAAAGAGGCAATCGCCGCGTTACGCGCGCAACCAGACGTACTTC
AGCTCGACAAATTTAGTCCGCAACAGGCAACTGAAATTGCGCAAATAGCACCGTCGCTGGCTCCTCACTGCACGCTGGCT
CTGACCGGTGGAATTAATCTGACGACACTCAAAAATTACCTCGACTGCGGCATTCGCCTTTTTATTACCTCCGCGCCTTA
TTACGCGGCACCGGCTGACATTAAAGTCAGTCTGCAACCCGCAGCCTCTATTTAA

Upstream 100 bases:

>100_bases
TATATCGCTGGTATCAACAACAAGATGCTCGTGCCCTCGCCCCTGCCAGCCGCGACTGGGCGCTCATCTGGTGGGATAGC
GTACCGCAAGAGGCACTGCG

Downstream 100 bases:

>100_bases
TTCTTTGTTAAACGGAATTTATTCTATGAGACTCAAAAAACGTTATCTCTGCACAGCATTATCACTTGCCTTTACCCAGC
AGGCCGTAGCGGCTCAGGAG

Product: molybdenum transport protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGGCVSGVSVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLTQMLALLRERYPDGNIACTRKAIPGTRLLASQAILTAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI

Sequences:

>Translated_284_residues
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGGCVSGVSVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLTQMLALLRERYPDGNIACTRKAIPGTRLLASQAILTAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
>Mature_284_residues
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGGCVSGVSVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAVQNVLEWSCGVSDYLTQMLALLRERYPDGNIACTRKAIPGTRLLASQAILTAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=263, Percent_Identity=24.7148288973384, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786299, Length=200, Percent_Identity=27.5, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=259, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 30579; Mature: 30579

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGGCVSGVSVACKMLTTLG
CEEECCHHHHHHHHHHCCCCCEEHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
LTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEWSCGVSDYLTQMLALLRER
CEEHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDGNIACTRKAIPGTRLLASQAILTAGGLIHRAGCAETILLFANHRHFLHDNQDWSGAI
CCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHH
NQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEE
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
EECCCCHHHHHHHHCCCEEEEEECCCCEECCCCEEEEECCCCCC
>Mature Secondary Structure
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGGCVSGVSVACKMLTTLG
CEEECCHHHHHHHHHHCCCCCEEHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
LTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEWSCGVSDYLTQMLALLRER
CEEHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YPDGNIACTRKAIPGTRLLASQAILTAGGLIHRAGCAETILLFANHRHFLHDNQDWSGAI
CCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHCCCCCCHHHHH
NQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
HHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEE
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
EECCCCHHHHHHHHCCCEEEEEECCCCEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA