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The map label for this gene is artM [H]

Identifier: 218704288

GI number: 218704288

Start: 1087023

End: 1087691

Strand: Reverse

Name: artM [H]

Synonym: ECUMN_1054

Alternate gene names: 218704288

Gene position: 1087691-1087023 (Counterclockwise)

Preceding gene: 218704289

Following gene: 218704287

Centisome position: 20.91

GC content: 52.62

Gene sequence:

>669_bases
ATGTTTGAGTATTTACCCGAACTGATGAAAGGGCTGCACACCAGCCTGACGCTAACCGTTGCCTCGCTGATTGTGGCACT
GATTCTGGCGTTGATTTTTACCATCATCCTGACGCTGAAAACGCCGGTACTGGTGTGGCTGGTGCGGGGTTATATCACGC
TGTTTACCGGTACGCCGCTGCTGGTGCAGATCTTCCTGATTTATTACGGGCCGGGCCAGTTCCCGACGTTGCAGGAGTAT
CCGGCACTGTGGCATTTGCTGTCAGAACCGTGGCTGTGTGCGCTGATTGCGTTGTCGCTGAACAGTGCAGCGTATACCAC
GCAGCTGTTTTACGGTGCCATTCGTGCGATCCCGGAAGGTCAGTGGCAGTCCTGTAGCGCCCTGGGAATGAGCAAAAAAG
ATACGCTAGCGATCCTGCTGCCGTATGCCTTTAAACGCTCGCTCTCTTCTTATTCCAACGAAGTGGTGCTGGTGTTCAAA
AGTACCTCTCTGGCTTACACCATTACGCTGATGGAAGTGATGGGATACAGCCAGTTGTTGTACGGACGCACCTACGATGT
CATGGTGTTCGGTGCGGCAGGGATTATTTATCTGATTGTTAACGGTCTGTTGACGCTGATGATGCGTCTGATCGAGCGCA
AAGCACTGGCATTCGAACGGCGGAATTAA

Upstream 100 bases:

>100_bases
TTGTGGCGGCGGCGATTTACCTGGTGATCACCCTGCTCAGTCAGTACATTCTCAAACGCATTGACCTGCGCGCGACACGT
TTTGAGCGGAGGCCTGGCTA

Downstream 100 bases:

>100_bases
TGTAGCTGCGTGCTGATGCCGGATGCGTCGTGGACGTCTTATCCGACCTGCATAGTGCATAAATTCTTATAATGAAGACG
GACAACTCACTAAGTTGTCC

Product: arginine permease ArtM

Products: ADP; phosphate; L-arginine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAFERRN

Sequences:

>Translated_222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAFERRN
>Mature_222_residues
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAFERRN

Specific function: Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787086, Length=222, Percent_Identity=99.5495495495496, Blast_Score=442, Evalue=1e-126,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=33.9366515837104, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=32.2115384615385, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787087, Length=237, Percent_Identity=29.1139240506329, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=26.7605633802817, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788646, Length=222, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786874, Length=218, Percent_Identity=26.605504587156, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786873, Length=216, Percent_Identity=24.537037037037, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24928; Mature: 24928

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAFERRN
HCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEG
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
QWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLL
CCCCHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
YGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAFERRN
HCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine [Periplasm]; H2O [C]

Specific reaction: ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]