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The map label for this gene is kdpE [H]

Identifier: 218704015

GI number: 218704015

Start: 828620

End: 829297

Strand: Reverse

Name: kdpE [H]

Synonym: ECUMN_0776

Alternate gene names: 218704015

Gene position: 829297-828620 (Counterclockwise)

Preceding gene: 218704016

Following gene: 218704011

Centisome position: 15.94

GC content: 55.6

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCTATTCGTCGCTTTCTGCGCACGGCGCTGGAGGGCGATAGGATGCG
CGTCTTTGAGGCCGAAACGCTGCAACGCGGCTTGCTGGAAGCGGCTACCCGTAAGCCAGATTTGATTATTCTCGATCTCG
GCCTGCCCGATGGTGATGGGATTGAGTTTATCCGCGACCTGCGCCAGTGGAGCGCGGTGCCGGTGATTGTGCTTTCCGCA
CGTAGCGAAGAGAGCGATAAAATCGCCGCGCTGGATGCCGGAGCGGATGATTACCTGAGTAAGCCATTTGGTATTGGCGA
ATTGCAGGCCCGTCTGCGCGTCGCATTACGCCGCCACTCTGCCACCACCACGCCCGATCCGCTGGTGAAATTTTCCAATG
TTACCGTCGATTTAGCGGCTCGAGTGATCCATCGCGGTGAGGAAGAGGTGCATCTCACCCCGATTGAGTTCCGCCTGCTG
GCGGTGTTGCTTAATAATGCGGGAAAAGTGCTCACCCAGCGCCAGCTACTTAACCAGGTGTGGGGGCCAAACGCGGTCGA
ACACAGTCATTATTTGCGTATTTATATGGGGCATCTGCGACAAAAACTGGAGCAAGATCCCGCCCGCCCCCGCCACTTCA
TTACTGAAACCGGTATTGGGTATCGGTTTATGCTTTAG

Upstream 100 bases:

>100_bases
GCACCATTACCGCGTTCAACCGACCGGAAGGTGGTGCCTGTTTTCGTGTTACACTTCCCCAGCAAACTGCCCCTGAACTT
GAAGAATTTCATGAGGATAT

Downstream 100 bases:

>100_bases
GGTCTGAATTGCCGGATGCGGCGTGAACGCCTTATCCGACCTACACATCGTCCCGTAGGCATGATAAGACGCGTCAGCGT
CGCATCAGGCATGGCACTCA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRTALEGDRMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTTPDPLVKFSNVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRTALEGDRMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTTPDPLVKFSNVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
>Mature_224_residues
TNVLIVEDEQAIRRFLRTALEGDRMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTTPDPLVKFSNVTVDLAARVIHRGEEEVHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=98.6666666666667, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=35.8744394618834, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.8214285714286, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.7713004484305, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=33.7662337662338, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.5855855855856, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.5315315315315, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=34.5454545454545, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=33.6363636363636, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.4410480349345, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=29.8245614035088, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=30.7017543859649, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=33.0578512396694, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=30.1470588235294, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25491; Mature: 25360

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRTALEGDRMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCC
ATTTPDPLVKFSNVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRTALEGDRMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCC
ATTTPDPLVKFSNVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]