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The map label for this gene is yajO [H]

Identifier: 218703702

GI number: 218703702

Start: 496002

End: 496976

Strand: Reverse

Name: yajO [H]

Synonym: ECUMN_0458

Alternate gene names: 218703702

Gene position: 496976-496002 (Counterclockwise)

Preceding gene: 218703703

Following gene: 218703701

Centisome position: 9.55

GC content: 53.85

Gene sequence:

>975_bases
ATGCAATACAACCCCTTAGGAAAAACCGACCTTCGCGTTTCCCGACTTTGCCTCGGCTGTATGACCTTTGGCGAGCCAGA
TCGTGGTAATCACGCATGGACACTGCCGGAAGAGAGCAGTCGTCCCATAATTAAACGCGCGCTGGAAGGCGGCATAAATT
TCTTTGACACCGCCAATAGCTATTCCGATGGCAGCAGCGAAGAGATCGTTGGTCGCGCACTGCGGGATTTCGCCCGTCGT
GAAGACGTGGTCGTTGCCACCAAAGTGTTCCATCGCGTTGGTGATTTGCCGGAAGGATTATCCCGTGCGCAAATATTGCG
CTCTATCGACGACAGCCTGCGCCGTCTCGGCATGGATTATGTCGATATCCTGCAAATTCATCGCTGGGATTACAACACGC
CGATCGAAGAGACGCTGGAAGCCCTGAACGACGTGGTAAAAGCCGGGAAAGCGCGTTATATCGGCGCGTCATCCATGCAC
GCTTCGCAGTTTGCTCAGGCACTGGAACTACAAAAACAGCACGGCTGGGCGCAGTTTGTCAGTATGCAGGATCACTACAA
TCTGATTTATCGAGAAGAAGAGCGCGAGATGCTGCCACTGTGTTACCAGGAGGGCGTAGCGGTGATTCCATGGAGCCCGC
TGGCGCGGGGTCGTCTGACACGTCCGTGGGGAGAAACTACCGCACGACTGGTGTCTGATGAGGTGGGGAAAAATCTCTAT
AAAGAAAGCGATGAAAATGACGCGCAGATCGCAGAGCGGTTAACGGGCGTCAGTGAAGAACTGGGTGCAACACGAGCACA
AGTTGCGCTGGCCTGGTTGTTGAGTAAACGGGGCATTGCCGCACCGATTATCGGAACTTCGCGGGAAGAACAGCTTGATG
AGCTGCTGAACGCGGTGGATATCACCTTGAAGCCGGAACAGATTGCTGAACTGGAAACGCCGTATAAACCGCATCCGGTC
GTAGGATTTAAGTAA

Upstream 100 bases:

>100_bases
CGATGCCGCCGGTATGGAAGCCAAAATCAAGGCCTGGCTGGCATAATCCCTACTCCACTCCTGCTATGCTTAAGAAATTA
TTCATGGCAGGAGTGGCAGC

Downstream 100 bases:

>100_bases
ATTTCGCTTTTCAGCCATTTTATCTGCTGAATTCCCCATCGTCTGCGATGATGGGGACAACGTACCTCCCATCATCTTCT
GTAACCATAATCCACCTCTG

Product: aldoketo-oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKRGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Sequences:

>Translated_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKRGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK
>Mature_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKRGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=320, Percent_Identity=33.4375, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI27436962, Length=323, Percent_Identity=33.4365325077399, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI27436971, Length=332, Percent_Identity=33.7349397590361, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436966, Length=320, Percent_Identity=33.125, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=32.3809523809524, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=32.2683706070287, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI223718702, Length=280, Percent_Identity=28.2142857142857, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=27.5618374558304, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=33.8129496402878, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=99.6913580246914, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=35.4545454545455, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=33.9506172839506, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=28.1976744186047, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=28.9036544850498, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=28.4810126582279, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI212645785, Length=182, Percent_Identity=32.967032967033, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=304, Percent_Identity=23.0263157894737, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=38.9221556886228, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=31.5151515151515, Blast_Score=142, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=30.5084745762712, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=28.5714285714286, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=31.3008130081301, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6321052, Length=155, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.2463768115942, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.2463768115942, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646155, Length=285, Percent_Identity=32.6315789473684, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=30.2250803858521, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36480; Mature: 36480

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKRGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALELQKQHGWAQFV
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKRGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHPVVGFK
CCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]