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The map label for this gene is ppdD

Identifier: 218703365

GI number: 218703365

Start: 121675

End: 122115

Strand: Reverse

Name: ppdD

Synonym: ECUMN_0105

Alternate gene names: 218703365

Gene position: 122115-121675 (Counterclockwise)

Preceding gene: 218703366

Following gene: 218703364

Centisome position: 2.35

GC content: 53.06

Gene sequence:

>441_bases
ATGGACAAGCAACGCGGTTTTACACTTATCGAACTGATGGTGGTTATTGGCATCATTGCCATTTTAAGCGCCATTGGTAT
TCCCGCTTATCAAAACTACCTGCGCAAAGCCGCACTCACCGACATGCTACAAACCTTTGTGCCTTACCGTACCGCCGTAG
AGTTGTGCGCGCTGGAACATGGTGGATTAGATACCTGCGACGGTGGCAGTAATGGCATCCCCTCGCCTACCACCACCCGC
TATGTTTCAGCCATGAGTGTGGCAAAGGGCGTGGTGTCGCTGACCGGGCAAGAAAGTCTCAATGGGCTAAGCGTCGTCAT
GACGCCGGGTTGGGATAACGCAAACGGCGTCACCGGTTGGACGCGCAACTGCAATATTCAAAGTGACAGCGCATTGCAGC
AAGCCTGCGAAGATGTCTTCCGCTTTGATGACGCCAACTAA

Upstream 100 bases:

>100_bases
AAAAAACTCCGGAAGCTGCTTTCCCGTTTCGTTTTTTGCCCCTCGCTTGTGCTGATGGCGTTTGCCAAAGTAGCGCCAAC
CAAATCAAGGAGCGAAACAA

Downstream 100 bases:

>100_bases
GGAGCGGCAATGAATATTCCACAGCTCACCGCCCTGTGTCTGCGTTATCAGGGAGTCTTGCTGGATGCCAGCGAAGAGGT
GGTTCATGTTGCGGTGGTCG

Product: putative major pilin subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTR
YVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN

Sequences:

>Translated_146_residues
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTR
YVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN
>Mature_146_residues
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTR
YVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN

Specific function: Not yet known

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family

Homologues:

Organism=Escherichia coli, GI1786297, Length=146, Percent_Identity=100, Blast_Score=303, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPDD_ECOLI (P36647)

Other databases:

- EMBL:   L20834
- EMBL:   L28105
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D64733
- RefSeq:   AP_000769.1
- RefSeq:   NP_414650.1
- ProteinModelPortal:   P36647
- SMR:   P36647
- STRING:   P36647
- EnsemblBacteria:   EBESCT00000000847
- EnsemblBacteria:   EBESCT00000017473
- GeneID:   945817
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0104
- KEGG:   eco:b0108
- EchoBASE:   EB2031
- EcoGene:   EG12107
- eggNOG:   COG4969
- GeneTree:   EBGT00050000009851
- HOGENOM:   HBG741643
- OMA:   KADVELC
- ProtClustDB:   PRK10574
- BioCyc:   EcoCyc:EG12107-MONOMER
- Genevestigator:   P36647
- GO:   GO:0009289
- InterPro:   IPR012902
- InterPro:   IPR001120
- TIGRFAMs:   TIGR02532

Pfam domain/function: PF07963 N_methyl

EC number: NA

Molecular weight: Translated: 15622; Mature: 15622

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEH
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGW
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
TRNCNIQSDSALQQACEDVFRFDDAN
CCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEH
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGW
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
TRNCNIQSDSALQQACEDVFRFDDAN
CCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503