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The map label for this gene is sgrR [H]

Identifier: 218703331

GI number: 218703331

Start: 81548

End: 83227

Strand: Reverse

Name: sgrR [H]

Synonym: ECUMN_0072

Alternate gene names: 218703331

Gene position: 83227-81548 (Counterclockwise)

Preceding gene: 218703332

Following gene: 218703329

Centisome position: 1.6

GC content: 55.18

Gene sequence:

>1680_bases
TTGCGCAGGAGTTCCCCTTTTATGCCATCTGCTCGTCTGCAACAACAGTTCATCCGCCTGTGGCAATGCTGCGAGGGTAA
ATCGCAGGACACAACGCTCAACGAACTGGCAGCGTTATTGAGCTGCTCGCGTCGTCATATGCGTACCCTGCTCAACACCA
TGCAGGATCGCGGCTGGCTGACGTGGGAAGCGGAAGTCGGGCGCGGTAAACGCTCGCGTCTGACATTCCTCTATACCGGG
CTGGCGCTTCAGCAACAGCGGGCGGAAGACCTGCTGGAGCAGGATCGTATCGACCAACTAGTGCAGTTGGTTGGCGACAA
AGCGACTGTGCGGCAAATGCTGGTTTCTCATCTGGGCCGCAGCTTCCGCCAGGGGCGGCACATCCTGCGCGTGCTCTACT
ATCGTCCGTTGCGTAATCTGCTACCTGGCAGCGCATTGCGCCGTTCCGAAACCCATATTGCCCGGCAAATCTTCAGTTCG
CTAACGCGCATAAATGAGGAAAATGGGGAACTGGAAGCAGACATCGCCCACCACTGGCAGCAAATTTCACCGCTTCACTG
GCGTTTCTTTTTGCGTCCAGGAGTCCATTTTCATCATGGTCGTGAACTGGAAATGGACGACGTGATCGCCTCTTTAAAAC
GAATCAATACGCTGCCGCTCTATTCGCATATTGCTGACATTGTGTCGCCGACGCCCTGGACGCTGGATATCCATCTCACG
CAACCGGACCGCTGGTTACCGTTACTGCTGGGGCAAGTTCCGGCGATGATCCTGCCGCGCGAATGGGAAACCCTCAGCAA
CTTTGCCAGCCATCCCATCGGAACGGGTCCTTATGCGGTGATCCGCAACAGCAGCAATCAACTGAAAATTCAGGCATTCG
ACGACTTCTTTGGTTATCGGGCATTAATCGACGAAGTTAACGTCTGGGTCTTGCCGGAAATTGCTGATGACCCCGCGGGA
GGCCTGATGCTGAAAGGACCGCAAGACGAGGAAAAAGAGATTGAAAGCCGCCTTGAAGAAGGTTGTTACTATTTACTGTT
CGACAGCCGTACCCATCGCGGGGCGAATCAGCAAGTCAGAGACTGGATAAGCTATGTGCTTTCGCCGACCAATCTGGTTT
ATTTCGCCGAGGAACAGTACCAGCAGCTGTGGTTTCCGGCCTATGGGCTGCTTCCCCGTTGGCACCATACCCGCACCATA
AAGAGCGAAAAACCGGCTGGTCTGGAAAGCCTCACCCTGACCTTTTATCAGGATCACAGTGAGCATAGGGTGATTGCCGG
GATCATGCAGCAGATTCTGGCAAGTCACCAGGTCACGCTGGAAATCAAAGAGATCAGCTACGATCAGTGGCATGAAGGAG
AGATCGAGAGCGATATCTGGCTTAACAGCGCCAACTTTACGCTGCCGCTGGATTTTTCGCTATTCGCGCACCTGTGCGAG
GTGCCGCTGCTCCAACACTGTATTCCGATCGACTGGCAAGCCGACGCCGCCCGCTGGCGCAATGGCGAAATGAACCTGGC
GAACTGGTGCCAGCAACTGGTCGCCAGCAAAGCAATGGTGCCGCTTATCCACCACTGGCTGATTATTCAGGGACAACGCA
GTATGCGCGGCCTGCGCATGAACACCCTCGGCTGGTTCGATTTTAAATCAGCGTGGTTTGCGCCGCCGGATCCAGAGTAG

Upstream 100 bases:

>100_bases
CGCGGTAAAATAGTGCTGATAAAACTGACGCATGGGGCACCTCCTTGCTTCATCGTTAGGAATTATTGACTTAATATAGG
GAAAATAAAATTGCTGTCTT

Downstream 100 bases:

>100_bases
CTTGCGCCTTTTGGCGGTCATGAGCGCATTTTTTATATTTAGACGGAATGAATAAAATACATTACTTTTATATTTTCTCT
GTTTTATGCATCGTCTGATT

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPEIADDPAG
GLMLKGPQDEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWISYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHTRTI
KSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Sequences:

>Translated_559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPEIADDPAG
GLMLKGPQDEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWISYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHTRTI
KSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>Mature_559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSSNQLKIQAFDDFFGYRALIDEVNVWVLPEIADDPAG
GLMLKGPQDEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWISYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHTRTI
KSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=551, Percent_Identity=98.1851179673321, Blast_Score=1123, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=578, Percent_Identity=26.9896193771626, Blast_Score=179, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 65056; Mature: 65056

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGR
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
QISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLT
HCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEC
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSSNQLKIQAFDDFFGYR
CCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEHHHHHHH
ALIDEVNVWVLPEIADDPAGGLMLKGPQDEEKEIESRLEEGCYYLLFDSRTHRGANQQVR
HHHHCCCEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
DWISYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHTRTIKSEKPAGLESLTLTFYQDHS
HHHHHHHCCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
EHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
CCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHH
VPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRM
HHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEE
NTLGWFDFKSAWFAPPDPE
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGR
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
QISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLT
HCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEC
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSSNQLKIQAFDDFFGYR
CCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEEHHHHHHH
ALIDEVNVWVLPEIADDPAGGLMLKGPQDEEKEIESRLEEGCYYLLFDSRTHRGANQQVR
HHHHCCCEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
DWISYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHTRTIKSEKPAGLESLTLTFYQDHS
HHHHHHHCCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
EHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
CCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHH
VPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRM
HHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEE
NTLGWFDFKSAWFAPPDPE
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]