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The map label for this gene is relB [H]

Identifier: 218702940

GI number: 218702940

Start: 4911857

End: 4912096

Strand: Direct

Name: relB [H]

Synonym: ECIAI39_4711

Alternate gene names: 218702940

Gene position: 4911857-4912096 (Clockwise)

Preceding gene: 218702939

Following gene: 218702946

Centisome position: 95.71

GC content: 49.17

Gene sequence:

>240_bases
ATGGCCACACTTAACGTCCGCCTGGATGACAAACTGAAAAATGAGGCTTATGCGGTGCTGGAAAAATTAAATATCACGCC
TACTGAAGCCGTACGGCTGCTGTTTCAGTACGTTGCGGAAAATGGACGAATGCCGGTAAAAACGCTCACTGTCAGTGATA
GTGAAGAAGCCTTGTTACGCACTGTCAGGGAACGACTGGCCAACCCACAAGAGGCCATTAAGGTCCGACTGGATGAGTGA

Upstream 100 bases:

>100_bases
TGCGTGTCGACGCCATTTTTGCGAGGCGTTTTCCAGAAATGAATGTAATGCATATGTAATGCTATAATGCATTACACTTT
TCATAATTACCGGAGGCATA

Downstream 100 bases:

>100_bases
TTAACGCAAATGATGCACCACCTGATTGCTGCTGCCGCGCCAGATCAGGGAAGGGTCTTTTAAATCCTGCACAAATTTGC
CGTCGACCAGCACGTTAATC

Product: bifunctional antitoxin/transcriptional repressor RelB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPQEAIKVRLDE

Sequences:

>Translated_79_residues
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPQEAIKVRLDE
>Mature_78_residues
ATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPQEAIKVRLDE

Specific function: Counteracts the effect of relE by means of direct protein-protein interaction, enabling the reversion of translation inhibition. Also acts as an autorepressor of relBE transcription. Increased transcription rate of relBE and activation of relE is consiste

COG id: COG3077

COG function: function code L; DNA-damage-inducible protein J

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787847, Length=79, Percent_Identity=46.8354430379747, Blast_Score=82, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007337 [H]

Pfam domain/function: PF04221 RelB [H]

EC number: NA

Molecular weight: Translated: 9013; Mature: 8881

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLR
CCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
TVRERLANPQEAIKVRLDE
HHHHHHCCHHHHHEEECCC
>Mature Secondary Structure 
ATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTLTVSDSEEALLR
CEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
TVRERLANPQEAIKVRLDE
HHHHHHCCHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574 [H]