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The map label for this gene is papB

Identifier: 218702821

GI number: 218702821

Start: 4785345

End: 4785659

Strand: Direct

Name: papB

Synonym: ECIAI39_4586

Alternate gene names: 218702821

Gene position: 4785345-4785659 (Clockwise)

Preceding gene: 218702820

Following gene: 218702822

Centisome position: 93.24

GC content: 44.76

Gene sequence:

>315_bases
ATGGCGCATCATGAAGTCATCAGTCGGTCAGGAAATGCGTTTTTGCTGAATATACGCGAGAGCGTACTGTTGCCCGGGTC
TATGTCTGAAATGCATTTTTTTTTACTGATAGGTATTTCTTCTATTCACAGTGACAGGGTCATTCTGGCTATGAAGGACT
ATCTGGTAGGTGGGCACTCCCGTAAGGAGGTCTGCGAGAAATACCAGATGAATAATGGGTATTTCAGTACAACACTGGGG
AGACTTATACGGCTGAATGCTCTTGCAGCAAGGCTTGCACCTTATTATACAGATGAGTCCTCGGCATTTGACTAA

Upstream 100 bases:

>100_bases
AATCAATATTTACAACATAAAAAACTAAATTTAACTTATTGCGTGAAGAGTATTTCCGGGCCGGAAGCATATATCCAGGG
GCCCGACAGAAGGGGGAAAC

Downstream 100 bases:

>100_bases
ATTATGGCATTCCGGAGTTTCTGGAAGATAAAAAAAGAAGCCCTTATCAGAAAGCAGACAGGTTATATCAGTATTCTGTC
GATAAATAACCTGCCCTGAA

Product: pap operon regulatory protein PapB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLG
RLIRLNALAARLAPYYTDESSAFD

Sequences:

>Translated_104_residues
MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLG
RLIRLNALAARLAPYYTDESSAFD
>Mature_103_residues
AHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLGR
LIRLNALAARLAPYYTDESSAFD

Specific function: May act as both positive and negative regulator of pap transcription. Might positively regulate levels of papI and/or mbf. Its autoregulatory mode of action involves differential binding to separate sites

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAPB_ECOLX (P04744)

Other databases:

- EMBL:   X03391
- EMBL:   X61239
- EMBL:   X55249
- EMBL:   M63747
- PIR:   B25121
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR004356
- PRINTS:   PR01554

Pfam domain/function: PF03333 PapB

EC number: NA

Molecular weight: Translated: 11696; Mature: 11564

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS
CCCCHHHHCCCCEEEEEECCCEECCCCCHHHEEEEEEECCCCCCCEEEEEEECHHCCCCC
RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSAFD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS
CCCHHHHCCCCEEEEEECCCEECCCCCHHHEEEEEEECCCCCCCEEEEEEECHHCCCCC
RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSAFD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2868893; 1357526; 2568258