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The map label for this gene is rbsC

Identifier: 218702601

GI number: 218702601

Start: 4540196

End: 4541161

Strand: Direct

Name: rbsC

Synonym: ECIAI39_4355

Alternate gene names: 218702601

Gene position: 4540196-4541161 (Clockwise)

Preceding gene: 218702600

Following gene: 218702602

Centisome position: 88.47

GC content: 53.11

Gene sequence:

>966_bases
ATGACAACCCAGACTGTCTCTGGTCGCCGTTATTTCACGAAAGCGTGGCTGATGGAGCAGAAATCGCTTATCGCTCTGCT
GGTGCTGATCGCGATTGTCTCGACGTTAAGCCCGAACTTTTTCACCATCAATAACTTATTCAATATTCTCCAGCAAACCT
CGGTAAACGCCATTATGGCAGTCGGGATGACGCTGGTGATCCTGACGTCGGGCATCGACTTGTCGGTAGGTTCTCTATTG
GCGCTGACCGGCGCAGTTGCTGCATCTATCGTTGGCATTGAAGTCAATGCGCTGGTGGCTGTCGCTGCCGCTCTCGCGTT
AGGTGCCGCAATTGGTGCGGTAACCGGGGTGATTGTAGCGAAAGGTCGCCTCCAGGCCTTTATCGCTACGCTGGTTATGA
TGCTTTTACTGCGCGGCGTGACCATGGTTTATACCAACGGTAGCCCAGTGAATACTGGCTTTACTGAGAACGCCGATCTG
TTTGGCTGGTTTGGTATTGGTCGTCCGCTGGGCGTACCGACGCCAGTCTGGATCATGGGAATTGTCTTCCTCGCGGCCTG
GTACATGCTGCATCACACGCGTCTGGGGCGTTACATCTACGCGCTGGGCGGCAACGAAGCGGCAACGCGTCTTTCTGGTA
TCAACGTCAATAAAATCAAAATCATCGTCTATTCTCTTTGTGGTCTGCTGGCATCGCTGGCCGGGATCATTGAAGTGGCG
CGTCTCTCCTCCGCACAACCCACGGCGGGGACTGGCTATGAGCTGGATGCTATTGCTGCGGTGGTTCTGGGCGGTACGAG
TCTGGCGGGCGGAAAAGGTCGCATTGTTGGGACGTTGATCGGCGCATTAATTCTTGGCTTCCTTAATAATGGATTGAATT
TGTTAGGTGTTTCCTCCTATTACCAGATGATCGTCAAAGCGGTGGTGATTTTGCTGGCGGTGCTGGTAGACAACAAAAAG
CAGTAA

Upstream 100 bases:

>100_bases
GGGCATCTCAGCGGGGAATTTACTCGTGAGCAGGCCACCCAGGAAGTGTTAATGGCTGCCGCTGTGGGCAAGCTTAATCG
CGTGAATCAGGAGTAAAAAA

Downstream 100 bases:

>100_bases
TAACGACTACAGGACATCTTGAATATGAATATGAAAAAACTGGCTACCCTGGTTTCCGCTGTTGCGCTAAGCGCCACCGT
CAGTGCGAATGCGATGGCAA

Product: ribose ABC transporter permease

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL
ALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRLQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK
Q

Sequences:

>Translated_321_residues
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL
ALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRLQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK
Q
>Mature_320_residues
TTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA
LTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRLQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLF
GWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVAR
LSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=321, Percent_Identity=99.6884735202492, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1790524, Length=315, Percent_Identity=40.3174603174603, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788896, Length=315, Percent_Identity=39.0476190476191, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI145693152, Length=310, Percent_Identity=35.8064516129032, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789992, Length=359, Percent_Identity=35.0974930362117, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=36.5131578947368, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI145693214, Length=326, Percent_Identity=36.8098159509202, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788471, Length=323, Percent_Identity=36.2229102167183, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787793, Length=292, Percent_Identity=33.9041095890411, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787794, Length=292, Percent_Identity=28.7671232876712, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 33466; Mature: 33335

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
VGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRLQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMG
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
IVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSY
HHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHH
YQMIVKAVVILLAVLVDNKKQ
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
VGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGRLQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMG
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
IVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSY
HHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHH
YQMIVKAVVILLAVLVDNKKQ
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]