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The map label for this gene is ade

Identifier: 218702509

GI number: 218702509

Start: 4439555

End: 4441321

Strand: Direct

Name: ade

Synonym: ECIAI39_4265

Alternate gene names: 218702509

Gene position: 4439555-4441321 (Clockwise)

Preceding gene: 218702506

Following gene: 218702518

Centisome position: 86.51

GC content: 54.78

Gene sequence:

>1767_bases
ATGAATAATTCTATTAACCATAAATTTCATCACATTAGCCGGGCTGAATACCAGGAATTGTTAGCCGTTTCCCGTGGAGA
CGCTGTTGCCGATTATATTATTGATAATGTCTCTATTCTCGACCTGATCAATGGCGGAGAAATTTCCGGCCCAATTGTGA
TTAAAGGACGTTACATTGCCGGTGTTGGCGCAGAATACGCTGATGCTCCGGCGTTGCAGCGGATTGATGCCCGCGGCGCA
ACGGCGGTGCCAGGGTTTATTGATGCTCACCTGCATATTGAATCCAGCATGATGACGCCGGTCACTTTTGAAACCGCGAC
CCTGCCGCGCGGCCTGACGACCGTTATTTGCGACCCTCATGAAATCGTCAACGTGATGGGCGAAGCCGGATTCGCCTGGT
TTGCCCGCTGTGCCGAACAGGCAAGGCAAAACCAGTACTTACAGGTCAGCTCTTGCGTACCCGCCCTGGAAGGCTGCGAT
GTTAACGGTGCCAGTTTTACCCTTGAACAGATGCTCGCCTGGCGGGACCATCCGCAGGTTACCGGCCTTGCAGAAATGAT
GGACTACCCTGGCGTAATTAGCGGGCAGAATGCGCTGCTCGATAAACTGGACGCATTTCGCCACCTGACGCTGGACGGTC
ACTGCCCGGGTTTGGGTGGTAAAGAACTTAACGCCTATATTGCTGCGGGTATTGAAAACTGCCACGAAAGTTATCAGTTG
GAAGAAGGACGCCGGAAATTGCAACTCGGCATGTCATTGATGATCCGTGAAGGGTCCGCAGCCCGCAATCTCAACGCGCT
GGCACCGTTGATCAACGAATTTAACAGCCCGCAATGCATGCTCTGTACCGATGACCGTAACCCGTGGGAGATCGCCCATG
AAGGACACATCGATGCCTTAATTCGCCGCCTGATCGAACAACACAATGTACCGCTGCATGTGGCATATCGCGTAGCCAGC
TGGTCGACGGCGCGCCATTTTGGTCTGAATCACCTCGGCTTACTGGCACCCGGCAAGCAGGCCGATATCGTCCTGTTGAG
CGATGCGCGTAAGGTCACGGTGCAGCAGGTACTGGTGAAAGGCGAGCCGATCGATGCGCAAACCTTACAGGCGAAAGAGT
CGGCGAGACTGGCACAATCCGCCCCGCCATATGGCAATACCATTTCCCGCCAGCCAGTTTCCGCCAGCGACTTTGCCCTG
CAATTCACGCCCGGAAAACGCTATCGGGTCATTGACGTCATCCATAACGAATTGATTACCCACTCCCGCTCCAGCGTCTA
CAGCGAAAATGGTTTTGATCGCGATGATGTGTGCTTTATTGCCGTACTTGAGCGTTACGGGCAACGGCTGGCTCCGGCCT
GTGGTTTGCTCGGCGGCTTTGGCCTGAATGAAGGTGCGCTGGCGGCGACGGTCAGCCATGACAGCCATAATATTGTGGTG
ATAGGTCGTAGCGCAGAAGAGATGGCGCTGGCGGTCAATCAGGTGATTCAGGATGGCGGCGGGCTGTGCGTGGTCCGTAA
CGGTCAGGTACAAAGTCATCTACCGTTGCCCATTGCCGGGCTAATGAGCACCGACACGGCGCAGTCACTGGCGGAGCAAA
TTGACGCCTTGAAAGCCGCCGCCCGTGAATGCGGTCCGTTACCCGATGAGCCGTTTATTCAGATGGCGTTTCTTTCTCTA
CCAGTGATCCCCGCGCTGAAACTAACCAGTCAGGGGCTGTTTGATGGCGAGAAGTTTGCCTTCACTACGCTGGAAGTCAC
GGAATAA

Upstream 100 bases:

>100_bases
TCACATTTCAATTGCACATTAATGGATATTCTTTAATAATCTCGCGACGTTTCTTTATGATAAATAATAATCAAATTGAT
AAAATCAAAATGAGAAAAAT

Downstream 100 bases:

>100_bases
TAAAAAAAAGCCCGGCGTCATGCCGGGCAAAAGTCACCAGTTACGTTTATGCCACTGTCAACTGCTGAATTTTTTTCTCG
CGGCGGATTTTGCGTTCTTC

Product: cryptic adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAKESARLAQSAPPYGNTISRQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Sequences:

>Translated_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAKESARLAQSAPPYGNTISRQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE
>Mature_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAKESARLAQSAPPYGNTISRQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=588, Percent_Identity=98.9795918367347, Blast_Score=1201, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 63730; Mature: 63730

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAKESARLAQSAPPYGNTISRQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAKESARLAQSAPPYGNTISRQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA