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The map label for this gene is envC

Identifier: 218702382

GI number: 218702382

Start: 4304957

End: 4306216

Strand: Direct

Name: envC

Synonym: ECIAI39_4134

Alternate gene names: 218702382

Gene position: 4304957-4306216 (Clockwise)

Preceding gene: 218702381

Following gene: 218702383

Centisome position: 83.88

GC content: 57.3

Gene sequence:

>1260_bases
ATGACACGGGCCGTGAAACCGCGCAGGTTTGCAATCAGGCCCATCATCTACGCCAGCGTTCTTAGCGCTGGCGTATTGTT
GTGCGCCCTTTCCGCCCACGCGGATGAGCGTGACCAACTCAAATCTATTCAGGCCGATATCGCCGCGAAAGAGCGCGCGG
TACGCCAAAAGCAACAACAACGCGCAAGCCTGCTCGCACAATTGAAAAAGCAGGAAGAGGCGATCTCTGAAGCCACTCGC
AAACTGCGCGAAACGCAAAATACGCTCAATCAACTCAATAAACAGATTGATGAGATGAACGCGTCGATTGCCAAACTGGA
GCAGCAAAAAGCCGCCCAGGAGCGCAGCCTCGCCGCGCAACTGGATGCCGCGTTTCGTCAGGGTGAACATACCGGTATTC
AGCTGATTCTCAGCGGTGAAGAAAGCCAGCGTGGGCAGCGGTTACAGGCTTATTTCGGCTATCTCAACCAGGCGCGACAA
GAAACCATTGCTCAGTTGAAACAAACGCGTGAAGAAGTCGCTATGCAGCGTGCCGAACTGGAAGAGAAACAGAGCGAGCA
ACAAACGCTTTTATATGAGCAGCGCGCCCAACAGGCGAAGCTGACCCAGGCGTTGAGCGAGCGTAAAAAGACGCTGGCAG
GGCTGGAGTCTTCCATCCAGCAAGGTCAGCAACAGTTGAGCGAGCTGCGCGCCAACGAATCCCGCCTGCGTAACAGCATT
GCCCGTGCGGAAGCTGCGGCGAAAGCGCGTGCTGAACGTGAAGCGCGCGAAGCCCAGGCGGTTCGCGACCGCCAGAAAGA
AGCGACGCGCAAAGGCACCACCTACAAGCCGACCGAAAGCGAAAAATCGCTGATGTCCCGTACCGGTGGTCTGGGCGCAC
CGCGCGGTCAGGCATTCTGGCCAGTTCGCGGGCCAACGCTGCATCGCTATGGCGAACAGCTACAGGGTGAATTACGCTGG
AAAGGGATGGTGATTGGTGCCTCTGAAGGTACTGAAGTTAAAGCGATTGCCGACGGCCGGGTGATTCTGGCTGACTGGCT
GCAAGGTTACGGTCTGGTGGTGGTGGTTGAGCACGGTAAAGGCGACATGAGTCTTTACGGCTATAATCAGAGCGCACTGG
TGAGCGTTGGTTCGCAGGTTCGCGCGGGCCAGCCAATTGCACTGGTGGGCAGCAGTGGCGGTCAGGGTCGGCCTTCACTC
TATTTCGAAATTCGCCGCCAGGGTCAGGCGGTCAATCCACAGCCGTGGTTGGGAAGATAA

Upstream 100 bases:

>100_bases
GTTGTCGCTGATGGGTATGGAAATCCCGCAAGAGATGACTGGTAAGCCGCTGTTCATCGTGGAATAATCCCTCCCCATGA
GGGGAAAGGCGATTAATACC

Downstream 100 bases:

>100_bases
GTTTTGTTTCCATTTCGTCGTAACGTTCTTGCATTTGCCGCTCTGTTGGCGCTCTCCTCCCCCGTAATTGCTGGCAAACT
TGCCATCGTCATTGATGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTRAVKPRRFAIRPIIYASVLSAGVLLCALSAHADERDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATR
KLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQ
ETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSELRANESRLRNSI
ARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRW
KGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSL
YFEIRRQGQAVNPQPWLGR

Sequences:

>Translated_419_residues
MTRAVKPRRFAIRPIIYASVLSAGVLLCALSAHADERDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATR
KLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQ
ETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSELRANESRLRNSI
ARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRW
KGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSL
YFEIRRQGQAVNPQPWLGR
>Mature_418_residues
TRAVKPRRFAIRPIIYASVLSAGVLLCALSAHADERDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRK
LRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQE
TIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSELRANESRLRNSIA
RAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWK
GMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLY
FEIRRQGQAVNPQPWLGR

Specific function: Unknown

COG id: COG4942

COG function: function code D; Membrane-bound metallopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0756 [H]

Homologues:

Organism=Escherichia coli, GI87082297, Length=419, Percent_Identity=99.5226730310263, Blast_Score=830, Evalue=0.0,
Organism=Escherichia coli, GI1789099, Length=115, Percent_Identity=39.1304347826087, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082174, Length=127, Percent_Identity=33.0708661417323, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 46534; Mature: 46403

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAVKPRRFAIRPIIYASVLSAGVLLCALSAHADERDQLKSIQADIAAKERAVRQKQQQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQTREEVAMQRAEL
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSELRANESRLRNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEC
PVRGPTLHRYGEQLQGELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGK
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCEEHHHHHHCCCEEEEEECCC
GDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR
CCEEEECCCHHHHHHHCHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TRAVKPRRFAIRPIIYASVLSAGVLLCALSAHADERDQLKSIQADIAAKERAVRQKQQQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQTREEVAMQRAEL
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSELRANESRLRNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEC
PVRGPTLHRYGEQLQGELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGK
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCEEHHHHHHCCCEEEEEECCC
GDMSLYGYNQSALVSVGSQVRAGQPIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR
CCEEEECCCHHHHHHHCHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]