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The map label for this gene is yiaM

Identifier: 218702343

GI number: 218702343

Start: 4259240

End: 4259713

Strand: Direct

Name: yiaM

Synonym: ECIAI39_4089

Alternate gene names: 218702343

Gene position: 4259240-4259713 (Clockwise)

Preceding gene: 218702342

Following gene: 218702344

Centisome position: 82.99

GC content: 44.3

Gene sequence:

>474_bases
ATGAAAAAAATACTTGAAGCAATACTGGCGATTAATCTCGCCGTACTTTCCTGTATTGTGTTTATAAACATTATTTTAAG
ATATGGTTTTCAGACAAGCATTTTATCTGTAGATGAATTGTCACGTTATTTATTTGTCTGGTTAACATTTATTGGCGCGA
TTGTGGCTTTTATGGATAACGCCCACGTTCAGGTCACCTTTCTGGTGGAGAAACTCTCCCCCGCATGGCAGCGACGAGTC
GCTCTGGTTACCCATTCCTTAATCTTATTTATTTGTGGCGCACTGGCCTGGGGCGCAACGCTAAAAACAATTCAGGACTG
GAGCGATTATTCACCGATCCTCGGTTTGCCCATCGGCCTGATGTATGCCGCTTGTCTGCCCACCAGCCTCGTTATCGCAT
TCTTTGAACTGCGTCATTTATATCAACTCATCACGCGTAGCAATTCTCTAACGTCGCCACCGCAAGGAGCTTAA

Upstream 100 bases:

>100_bases
CCAGAACGCCTGGGTAATGTTATTGCTCTAACTATATTAATAATTTAGGTTGCTGCACATGCAACTTGAATTATGACAGA
CATAGCCTCAAGGAATAGCT

Downstream 100 bases:

>100_bases
TCATGGCTGTGCTGATTTTTCTGGGCTGTCTGTTGGGTGGTATTGCTATCGGTTTGCCTATTGCCTGGGCACTGTTGTTG
TGCGGGGCGGCGTTAATGTT

Product: 2,3-diketo-L-gulonate TRAP transporter small permease YiaM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRV
ALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA

Sequences:

>Translated_157_residues
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRV
ALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA
>Mature_157_residues
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRV
ALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate

COG id: COG3090

COG function: function code G; TRAP-type C4-dicarboxylate transport system, small permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter small permease family

Homologues:

Organism=Escherichia coli, GI1790002, Length=157, Percent_Identity=100, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YIAM_ECOLI (P37674)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S47798
- RefSeq:   AP_004215.1
- RefSeq:   NP_418034.1
- ProteinModelPortal:   P37674
- STRING:   P37674
- EnsemblBacteria:   EBESCT00000003423
- EnsemblBacteria:   EBESCT00000003424
- EnsemblBacteria:   EBESCT00000017265
- GeneID:   948093
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3549
- KEGG:   eco:b3577
- EchoBASE:   EB2189
- EcoGene:   EG12281
- eggNOG:   COG3090
- GeneTree:   EBGT00050000011716
- HOGENOM:   HBG537868
- OMA:   PATGISM
- ProtClustDB:   PRK09877
- BioCyc:   EcoCyc:MONOMER0-422
- Genevestigator:   P37674
- GO:   GO:0006810
- InterPro:   IPR007387

Pfam domain/function: PF04290 DctQ

EC number: NA

Molecular weight: Translated: 17516; Mature: 17516

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x24f5b8ac)-; HASH(0x26045540)-; HASH(0x26452640)-; HASH(0x265dee9c)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGL
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGL
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503