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The map label for this gene is agaR [H]

Identifier: 218702028

GI number: 218702028

Start: 3920051

End: 3920881

Strand: Direct

Name: agaR [H]

Synonym: ECIAI39_3755

Alternate gene names: 218702028

Gene position: 3920051-3920881 (Clockwise)

Preceding gene: 218702021

Following gene: 218702029

Centisome position: 76.38

GC content: 48.26

Gene sequence:

>831_bases
ATGAAGAGTGTTAACGTGCCGAGAAAATCGTCTAACCTACTGAAACGCAGATTAAAAATTGCAGAAATTGTTGCCGCCCA
GGGTGAAATCAAAGTTGATGACTTATCTGCGCAACTTGGTGTCTCTGGCGTGACGATCCGCGGCGATCTCAGTTATCTGG
AGCAACAGGGATATTTAAAGCGATCATTTGGCGGTGCTATTGCGACACCACTCTCCTCTGAACCAGAAGCGACACAACCG
ATCGCACCATTGTCTCTGGCACAACAAATGGAAATAGCACGACATTGCGCACGATTAATTCGCGATCGTGACACGCTATT
TCTTGGACATGGGACAATCTGCCGTAAGATCATTCCCTTGCTCAGCGAAGTGAAAAAACTGCGTCTGATCACCAACGATC
CCGAACATGCGCTGCTGGCAAATCAGTTTATTGATGGCGAAATAATACTGGCTGGCAGTGAAATGCTGCGCCCCGACACC
GCACTGGCCGGAAAACAGCTTGAACAGGCACTTCAGCATTTCACCATTACACATAGCATTCTGGAAATCAGCCATCTGGA
TGCTGATGGTACTTTAAATATCAACGTTCCCAGACTCGCCGCTGCCTGGCAGCTCTGTTTCGATCATGCCCAGAATAAGA
CGGTTATCGTTGCCGCCGATCCTGCGCCATCAACGGCTGCTATCGGGCATTTGCATCAGGCAGAAAATGTGATCGTCAGC
CGCAGCATTAACGAACAATATCAGCAACAATTGCAGTCGGCTGATTTCGTTATCCTTTATACCAGTAATGAGTGCTTTAC
CTGGTCCAATCGCGAAAGGCTTCAGGAATGA

Upstream 100 bases:

>100_bases
GATTTTTGGCCCATGATTTTCTTTTCGAATTGTCGATATTATTGAAGGATAACTTTCAAAGAAAAATACAAGGGGCTATA
GTGTTACGCATTAAAGGCCA

Downstream 100 bases:

>100_bases
GAGGGGTTTTGTGACAATAACTATCTGCGCTATGGGCGAATTGCTGGCCGAGTTTTTGTCCCGCAACCCACATCAAAAAT
TCACTCAGCCTGGGGAGTTT

Product: putative DEOR-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGVTIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEATQP
IAPLSLAQQMEIARHCARLIRDRDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
ALAGKQLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVAADPAPSTAAIGHLHQAENVIVS
RSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE

Sequences:

>Translated_276_residues
MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGVTIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEATQP
IAPLSLAQQMEIARHCARLIRDRDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
ALAGKQLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVAADPAPSTAAIGHLHQAENVIVS
RSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
>Mature_276_residues
MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGVTIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEATQP
IAPLSLAQQMEIARHCARLIRDRDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
ALAGKQLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVAADPAPSTAAIGHLHQAENVIVS
RSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=178, Percent_Identity=32.0224719101124, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789059, Length=261, Percent_Identity=25.2873563218391, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789829, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787540, Length=165, Percent_Identity=31.5151515151515, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI226510968, Length=182, Percent_Identity=28.021978021978, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 30469; Mature: 30469

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGVTIRGDLSYLEQQGYLK
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCCEEEECHHHHHHHCCCHH
RSFGGAIATPLSSEPEATQPIAPLSLAQQMEIARHCARLIRDRDTLFLGHGTICRKIIPL
HHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
LSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDTALAGKQLEQALQHFTITHSI
HHHHHHHEEECCCCCHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHH
LEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVAADPAPSTAAIGHLHQAENVIVS
HHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEEEE
RSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
CHHHHHHHHHHHCCCEEEEEECCCEEECCCHHHHCC
>Mature Secondary Structure
MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGVTIRGDLSYLEQQGYLK
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCCCCEEEECHHHHHHHCCCHH
RSFGGAIATPLSSEPEATQPIAPLSLAQQMEIARHCARLIRDRDTLFLGHGTICRKIIPL
HHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
LSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDTALAGKQLEQALQHFTITHSI
HHHHHHHEEECCCCCHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHH
LEISHLDADGTLNINVPRLAAAWQLCFDHAQNKTVIVAADPAPSTAAIGHLHQAENVIVS
HHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEEEE
RSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
CHHHHHHHHHHHCCCEEEEEECCCEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]