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The map label for this gene is yghZ

Identifier: 218701775

GI number: 218701775

Start: 3652645

End: 3653685

Strand: Direct

Name: yghZ

Synonym: ECIAI39_3497

Alternate gene names: 218701775

Gene position: 3652645-3653685 (Clockwise)

Preceding gene: 218701763

Following gene: 218701777

Centisome position: 71.17

GC content: 52.55

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGAACGTTACGGGCAGATGCAGTACCGCTATTGCGGAAAAAGTGGTTTGCGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGTGCGATCCTGCGTAAAGCGTTTG
ATTTGGGCATTACGCACTTTGATTTAGCCAATAATTACGGGCCGCCTCCAGGAAGCGCAGAAGAGAACTTTGGTCGCCTG
CTGCGCGAGGATTTTGCCGCTTATCGCGATGAACTGATTATCTCTACCAAGGCTGGCTACGATATGTGGCCCGGCCCTTA
CGGCTCTGGCGGTTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTTGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATGCGGTACAAAGCGGT
AAGGCGCTGTATGTCGGGATCTCCTCTTACTCGCCAGAGCGGACGCAAAAAATGGTCGAGTTGCTGCGCGAGTGGAAAAT
TCCGCTGTTAATTCATCAACCTTCGTACAATTTACTGAACCGCTGGGTGGATAAAAGCGGCCTGCTGGATACCCTGCAAC
ATAACGGCGTGGGCTGCATTGCCTTTACTCCTCTGGCTCAGGGATTGCTGACCGGAAAATATCTCAACGGTATTCCGCAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGTCTGACGCCGAAAATGCTCACCGAAGCCAACCTCAACAGCCT
GCGCTTATTGAATGAAATGGCACAGCAGCGTGGACAATCAATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAGATGAGC
GAGTGACGTCGGTATTGATTGGTGCCAGCCGCGCGGAGCAACTTGAGGAGAACGTGCAGGCGCTGAATAATCTGACATTT
AGCACCGAGGAGCTGGCGCAGATTGATCAGCATATCGCCGATGGCGAGCTGAATCTGTGGCAGGCGTCTTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACTCTGTGAGCCAGACTACGGGATACGCGCTGGCGAATCGCTAAACTAGAAACATTGTTTCGAAATTG
AACGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CCTGTTAATAACGGGCGCGAGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATCA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQHNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQHNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQHNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=35.5623100303951, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4504825, Length=338, Percent_Identity=35.7988165680473, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=34.8765432098765, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=34.8765432098765, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=34.5679012345679, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=34.0490797546012, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=32.7014218009479, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI41327764, Length=213, Percent_Identity=31.4553990610329, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=29.3706293706294, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=99.1329479768786, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=35.7575757575758, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.0229885057471, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.7295597484277, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=24.1486068111455, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=23.7388724035608, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=25.0793650793651, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=25.2100840336134, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=24.7899159663866, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640980, Length=339, Percent_Identity=28.6135693215339, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=28.6135693215339, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=25.1497005988024, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=328, Percent_Identity=25.9146341463415, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38871; Mature: 38871

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQHNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHCHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
LLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQHNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHCHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]