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The map label for this gene is glcC

Identifier: 218701749

GI number: 218701749

Start: 3625882

End: 3626646

Strand: Direct

Name: glcC

Synonym: ECIAI39_3468

Alternate gene names: 218701749

Gene position: 3625882-3626646 (Clockwise)

Preceding gene: 218701742

Following gene: 218701751

Centisome position: 70.65

GC content: 55.56

Gene sequence:

>765_bases
ATGAAAGATGAACGTCGCCCTATTTGCGAAGTGGTTGCAGAGAGTATCGAACGGTTAATTATCGACGGCGTACTGAAGGT
CGGTCAGCCGCTTCCCTCGGAACGTCGACTGTGTGAAAAGCTCGGCTTCTCACGCTCCGCACTGCGTGAAGGGCTGACCG
TGCTGCGCGGGCGCGGGATTATTGAAACGGCGCAGGGTCGCGATTCTCGTGTCGCACGGCTTAATCGGGTGCAGGACACC
AGCCCGCTGATCCATCTGTTCAGTACGCAGCCGCGAACGCTGTACGATCTGCTCGACGTTCGCGCATTACTGGAGGGCGA
ATCGGCAAGGCTGGCGGCAACGCTGGGAACCCAGGCTGATTTTGTTGTGATAACCCGCTGTTATGAAAAAATGCTCGCCG
CCAGTGAGAACAACAAAGAGATTTCGCTGATCGAACATGCGCAGTTGGATCACGCTTTCCATCTCGCCATTTGTCAGGCT
TCTCACAATCAGGTGCTGGAGTTTACGCTGCAATCATTGACCGACCTGATGTTTAATTCGGTGTTTGCCAGCGTAAATAA
TCTCTACCATCGACCACAGCAAAAAAAGCAGATCGATCGCCAGCATGCGCGGATCTACAACGCGGTGTTGCAGCGGCTGC
CGCACGTCGCCCAGCGCGCAGCACGCGATCATGTGCGGACCGTGAAAAAGAATCTCCACGATATCGAGCTGGAAGGCCAC
CATTTGATTCGCTCGGCGGTGCCGCTGGAGATGAAGCAGGGGTGA

Upstream 100 bases:

>100_bases
ACTTAATGTTAAATTGATGTAACATAATCACTTACGTGATGTGCGTGTTTTGCGAGTTAAGAACAGAAAAATTGGTCCTA
CCTGTGCACGAGGTCCGGGA

Downstream 100 bases:

>100_bases
CTGCCATCAAATCTGCTTTTCATACAATCGGTAACGCTTGTACGGCTCCGCCCCAATGCGTTCCAGCATGTTATTCATGC
CTGTATTGGTTTCGAGGATC

Product: DNA-binding transcriptional regulator GlcC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
SHNQVLEFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMKQG

Sequences:

>Translated_254_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
SHNQVLEFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMKQG
>Mature_254_residues
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDT
SPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
SHNQVLEFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HLIRSAVPLEMKQG

Specific function: Activator for the glycolate oxidation locus [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789353, Length=252, Percent_Identity=99.2063492063492, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1790032, Length=234, Percent_Identity=31.1965811965812, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786303, Length=231, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790780, Length=257, Percent_Identity=29.1828793774319, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI48994955, Length=223, Percent_Identity=27.8026905829596, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082208, Length=244, Percent_Identity=24.1803278688525, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789621, Length=232, Percent_Identity=22.8448275862069, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28856; Mature: 28856

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQAD
EECCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
FVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQASHNQVLEFTLQSLTDLMFNS
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
HLIRSAVPLEMKQG
HHHHHHCCCCCCCC
>Mature Secondary Structure
MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQAD
EECCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
FVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQASHNQVLEFTLQSLTDLMFNS
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
HLIRSAVPLEMKQG
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]