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The map label for this gene is iucB

Identifier: 218701707

GI number: 218701707

Start: 3570901

End: 3571848

Strand: Direct

Name: iucB

Synonym: ECIAI39_3424

Alternate gene names: 218701707

Gene position: 3570901-3571848 (Clockwise)

Preceding gene: 218701706

Following gene: 218701708

Centisome position: 69.58

GC content: 56.43

Gene sequence:

>948_bases
ATGTCTGAGGCAAACATTATTCACAGCAGATATGGACTGCGCTGTGAAAAACTCGACAAGCCCCTGAATCTTGGCTGGGG
ACTGGACAATAGCGCGGTGTTGCACTGTCCCGGGGAGCTGCCGACAGGGTGGCTGTGCGATGCGCTGGATCAGATATTTA
TCGCCGCACCACAACTGTCAGCAGTGGCTCTCCCCTGGGCCGAATGGCGTGAGGAGCCACAGGCGCTGACGCTTTTTGGG
CAGGTAAAAAGCGACATTATCCATCGTACTGCCTTCTGGCAGTTACCGTTATGGTTGAGTTCACCGGCAAACCGGGCCTC
CGGTGAAATGGTTTTTGATGCAGAGCGTGAGATTTATTTCCCGCAGCGCCCACCCCGTCCACAGGGTGAGGTTTACCGCC
GTTACGATCCACGTATTCGCAGGATGCTGAGTTTCCGCATTGCCGATCCCGTTTCTGATGCAGAACGTTTCACCCGCTGG
ATGAATGATCCGCGCGTTGAGTATTTCTGGGAGCAAAGTGGCTCACTGGAGGTACAGACCGCCTATCTGGAGCGCCAGCT
CACCGGTAAACATGCATTCCCGCTGATTGGGTGCTTCGACGATCGGCCATTCAGCTATTTCGAAATCTACTGGGCGGCGG
AAGACCGCATTGGTCGTCACTATTCGTGGCAGCCCTTTGACCGTGGCCTGCATCTGCTGGTTGGTGAACAGCAATGGCGC
GGGGCCCACTATGTGCAAAGCTGGCTGCGCGGGCTGACACATTACCTGCTGCTGGATGAGCCCCGTACGCAGCGCACAGT
ACTGGAGCCACGCACCGATAACCAGCGCCTGTTCCGCCATCTTGAGCCTGCGGGATACCGGACAATTAAAGAGTTCGACT
TCCCACATAAGCGCTCGCGCATGGTGATGGCGGATCGTCATCACTTCTTCACGGAGGTCGGTCTGTAA

Upstream 100 bases:

>100_bases
CTTTTTCTGTTATCTGAACGATCATAACGAGAACACCATTGTTGACCCTTCGGTGATCTATTTCGATTTCGCTAACCCGC
TGCAGGCTCAGGAGGTCTGA

Downstream 100 bases:

>100_bases
TGAATCACAAGGACTGGGATTTTGTTAACCGTCGGCTGGTGGCAAAAATGTTGTCTGAGATGGAGTATGAGCAGGTTTTC
CACGCGGAATCTCAGGGCGA

Product: aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase

Products: CoA; N6-acetyl-N6-hydroxy-L-lysine

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFG
QVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL

Sequences:

>Translated_315_residues
MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFG
QVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL
>Mature_314_residues
SEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFGQ
VKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRWM
NDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWRG
AHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL

Specific function: Unknown

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iucB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR019432 [H]

Pfam domain/function: PF10331 AlcB [H]

EC number: 2.3.1.102

Molecular weight: Translated: 37233; Mature: 37101

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLS
CCCCCEEHHHHCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCC
AVALPWAEWREEPQALTLFGQVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYF
EEECCHHHHHCCCCEEEHHHHHHHHHHHHHHHEECCCEECCCCCCCCCCEEEECCCCEEC
PQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRWMNDPRVEYFWEQSGSLEVQT
CCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEH
AYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
HHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHCCEEEEECCHHHC
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSR
CHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCC
MVMADRHHFFTEVGL
EEEEHHHHHHHHCCC
>Mature Secondary Structure 
SEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLS
CCCCEEHHHHCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCC
AVALPWAEWREEPQALTLFGQVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYF
EEECCHHHHHCCCCEEEHHHHHHHHHHHHHHHEECCCEECCCCCCCCCCEEEECCCCEEC
PQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRWMNDPRVEYFWEQSGSLEVQT
CCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEH
AYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
HHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCHHCCEEEEECCHHHC
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSR
CHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCHHHHHHHCCCCCCCHHHHCCCCCCCCC
MVMADRHHFFTEVGL
EEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; N6-hydroxy-L-lysine

Specific reaction: acetyl-CoA + N6-hydroxy-L-lysine = CoA + N6-acetyl-N6-hydroxy-L-lysine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8003107 [H]