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The map label for this gene is insK [C]

Identifier: 218701669

GI number: 218701669

Start: 3531964

End: 3532854

Strand: Direct

Name: insK [C]

Synonym: ECIAI39_3378

Alternate gene names: 218701669

Gene position: 3531964-3532854 (Clockwise)

Preceding gene: 218701668

Following gene: 218701675

Centisome position: 68.82

GC content: 53.98

Gene sequence:

>891_bases
GTGATGCCACTGCTGGATAAGCTGCGTAAGCTGTACGGGGTCGGACCGGTATGCAGTGAACTACATATTGCCCCGTCAAC
GTATTACCACTGTCAGCAACAGCGACATCATCCTGATAAACGCAGTGCCCGTGCGCAGCGCGATGACTGGCTGAAGAAAG
AGATACTGCGCGTATACGATGGGAATCATCAGGTATACGGTGTGCGTAAAGTCTGGCGTCAGTTGTTACGGGAAGGAATC
AGGGTAGCCAGATGTACAGTGGCGCGCCTCATGGCGGTTATGGGACTTGCCGGTGTTCTCCGGGGTAAAAAGGTCCGCAC
TACCGTCAGCCGGAAAGCCGTTGCCGCAGGCGACCGCGTAAACCGTCAGTTTGTGGCAGAACGTCCTGACCAGTTGTGGG
TGGCTGATTTTACTTACGTCAGCACATGGCAGGGGGTCGTCTATGTGGCGTTCATCATTGATGTGTTTGCCGGATACATC
GTGGGGTGGCGGGTCTCATCGTCCATGGAAACGACATTCGTGCTGGATGCTCTGGAGCAGGCGTTATGGGCCCGTCGACC
GTCCGGCACAGTCCATCACAGTGATAAAGGTTCTCAGTATGTATCGCTGGCCTACACACAGCGGCTTAAGGAAGCCGGAT
TACTGGCATCAACAGGAAGTACTGGTGACTCGTATGACAACGCGATGGCGGAGAGCATCAATGGCCTTTACAAAGCGGAG
GTAATACACCGTAAGAGCTGGAAAAACCGTGCAGAAGTGGAACTGGCCACACTCACGTGGGTGGACTGGTATAACAATCG
ACGATTGCTGGAAAGGCTGGGCCATACTCCTCCGGCAGAAGCAGAAAAAGCTTATTATGCTTCCATCGGAAACGATGATC
TGGCAGCCTGA

Upstream 100 bases:

>100_bases
AGCTGGAACGTGAAAATCGTGAACTGCGCCGCAGTAACGATATCCTTCGCCAGGCTTCCGCTTATTTTGCGAAGGCGGAG
TTCGACCGCCTCTGGAAAAA

Downstream 100 bases:

>100_bases
GTTCACAGATAAAACACTCTCCAGGAAACCCGGGGCGGTTCATATTGCTAAACGCCGTGGCTACCCGCTTTCAGAAAGAG
CAACCTTTGCTCAGGCCTGT

Product: transposase ORF B, IS629

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MMPLLDKLRKLYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEILRVYDGNHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGVVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDLAA

Sequences:

>Translated_296_residues
MMPLLDKLRKLYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEILRVYDGNHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGVVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDLAA
>Mature_296_residues
MMPLLDKLRKLYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEILRVYDGNHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGVVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDLAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=260, Percent_Identity=50, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1789981, Length=286, Percent_Identity=29.3706293706294, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788405, Length=292, Percent_Identity=28.0821917808219, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787263, Length=292, Percent_Identity=28.0821917808219, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786753, Length=292, Percent_Identity=28.0821917808219, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786570, Length=292, Percent_Identity=28.0821917808219, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786490, Length=292, Percent_Identity=28.0821917808219, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33602; Mature: 33602

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPLLDKLRKLYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEILRVYD
CCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GNHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAAGDRV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
NRQFVAERPDQLWVADFTYVSTWQGVVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQ
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
ALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
HHHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDLAA
HHHHHHCCCCCCEEEEEEEEEHHHCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMPLLDKLRKLYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKKEILRVYD
CCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GNHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAAGDRV
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
NRQFVAERPDQLWVADFTYVSTWQGVVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQ
HHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
ALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
HHHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDLAA
HHHHHHCCCCCCEEEEEEEEEHHHCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]