Click here to switch to the map view.

The map label for this gene is glmU [H]

Identifier: 218701634

GI number: 218701634

Start: 3499935

End: 3500366

Strand: Direct

Name: glmU [H]

Synonym: ECIAI39_3342

Alternate gene names: 218701634

Gene position: 3499935-3500366 (Clockwise)

Preceding gene: 218701626

Following gene: 218701635

Centisome position: 68.2

GC content: 56.02

Gene sequence:

>432_bases
ATGATGACATTGCCCTACCCATATTCTTCCTCCGCACGTTTTTACGCGCTGCGCCTGCTCCCCGGGCAGGAAGTTCTCTC
CCAATTACGCGCCTTCGCGCAGCAACAACAACTTCACGCCGCGTGGATTGCAGGTTGTACCGGCAGTCTGACTGACGTCG
CCTTACGCTATGCCGGGCAAGAAAACACTGCCCTGCTAAGCGGTAAGTTCGAAGTCATCGCATTGAACGGCACGCTGGAA
CAGAGTGGTGAACATCTTCATCTCTGCGTTTCCGATCCACACGGCACGATGCTTGGCGGTCATATGATGCCCGGCTGTAC
CGTGCGGACCACGCTTGAACTGGTGATCGGCTGCCTTGAGGAACTGGCGTTTAGCCGCCAGCCTTGCGCGCTTTCTGGTT
ACGACGAGTTGCATATTTCCCCCGTTAACTAA

Upstream 100 bases:

>100_bases
AATCTTTTCGTTGTGCCGTCACAAACCCTGACTTATATCAGAATATGACTGATGCAGCGTCGATATTATCCGCAATACGT
CCGAGTTTCGGAGTACTCCA

Downstream 100 bases:

>100_bases
CTATTTTCAGAGAGGTTTTCTTATGGCGCGTCGCCACTTTTCCAGTCAGGCGCTGGTGTTAATCGTTATATCTATCGCCA
TCAATATGATCGGCGGGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIAGCTGSLTDVALRYAGQENTALLSGKFEVIALNGTLE
QSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGCLEELAFSRQPCALSGYDELHISPVN

Sequences:

>Translated_143_residues
MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIAGCTGSLTDVALRYAGQENTALLSGKFEVIALNGTLE
QSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGCLEELAFSRQPCALSGYDELHISPVN
>Mature_143_residues
MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIAGCTGSLTDVALRYAGQENTALLSGKFEVIALNGTLE
QSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGCLEELAFSRQPCALSGYDELHISPVN

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1661

COG function: function code R; Predicted DNA-binding protein with PD1-like DNA-binding motif

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005175
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF03479 DUF296; PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 15521; Mature: 15521

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIAGCTGSLTDVALRYAGQ
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ENTALLSGKFEVIALNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGCLE
CCCEEEECCEEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHH
ELAFSRQPCALSGYDELHISPVN
HHHCCCCCCEECCCCEEEEEECC
>Mature Secondary Structure
MMTLPYPYSSSARFYALRLLPGQEVLSQLRAFAQQQQLHAAWIAGCTGSLTDVALRYAGQ
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
ENTALLSGKFEVIALNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGCLE
CCCEEEECCEEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHH
ELAFSRQPCALSGYDELHISPVN
HHHCCCCCCEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA