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The map label for this gene is argK

Identifier: 218701624

GI number: 218701624

Start: 3489025

End: 3490020

Strand: Direct

Name: argK

Synonym: ECIAI39_3332

Alternate gene names: 218701624

Gene position: 3489025-3490020 (Clockwise)

Preceding gene: 218701623

Following gene: 218701625

Centisome position: 67.98

GC content: 53.31

Gene sequence:

>996_bases
ATGATTAATGAAGCCACGCTGGCAGAAAGTATTCGCCGCTTACGTCAGGGTGAGCGTGCCACGCTCGCCCAGGCCATGAC
GCTGGTGGAAAGCCGTCACCCGCGTCATCAGGCGCTAAGTACGCAACTGCTTGATGCCATTATGCCGTTCTGTGGTAACG
CCCTGCGACTGGGTGTTACCGGCACACCCGGCGCGGGGAAAAGTACCTTTCTTGAAGCCTTTGGCATGTTGTTGATTCGT
GAGGGACTAAAGGTTGCGGTTATTGCGGTCGATCCCAGCAGCCCGGTCACTGGCGGTAGCATTCTCGGAGATAAAACCCG
CATGAATGATCTGGCGCGTGCCGAGGCGGCGTTTATTCGCCCGGTACCCTCCTCCGGTCATCTGGGCGGTGCCAGTCAGC
GAGCGCGGGAATTAATGCTGTTATGCGAAGCGGCGGGTTATGACGTAGTGATTGTCGAAACGGTTGGCGTCGGACAGTCG
GAAACGGAAGTCGCCCGCATGGTGGACTGTTTTATCTCGTTGCAAATTGCCGGTGGCGGCGATGATCTGCAGGGCATTAA
AAAGGGGCTGATGGAAGTGGCAGATCTGATCGTTATCAACAAAGACGATGGCGATAACCATACCAATGTCGCCATTGCCC
AGCATATGTACGAGAGTGCCCTGCATATTCTGCGACACAAATACGACGAATGGCAGCCACGGGTTCTGACTTGTAGCGCA
CTGGAAAAACGTGGAATCAATGAGATCTGGCACGCCATCATCGACTTCAAAACCGCGCTAACTGCCAGTGGTCGTTTGCA
ACAAGTACGGCAACAACAATCAGTGGAATGGCTGCGTAAACAAACCGAAGAAGAAGTACTGAATCACCTGTTCGCGAATG
AAGATTTCGATCGCTATTACCGCCAGACGCTTTTAGCGGTCAAAAACAATACGCTCTCACCGCGCACCGGCCTGCGACAG
CTCAGTGAATTTATCCAGACGCAATATTTTGATTAA

Upstream 100 bases:

>100_bases
TACGCCTTCCTGCAGGAGCGCGGCGTGGCGGCGATTTATGGTCCAGGTACGCCTATGCTCGACAGCGTGCGCGACGTACT
GAATCTGATAAGCCAGCATC

Downstream 100 bases:

>100_bases
AGGAATTTTTATGTCTTATCAGTATGTGAACGTTGTCACTATCAACAAAGTGGCGGTCATTGAGTTTAACTATGGCCGAA
AACTTAATGCCTTAAGTAAA

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLLDAIMPFCGNALRLGVTGTPGAGKSTFLEAFGMLLIR
EGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYESALHILRHKYDEWQPRVLTCSA
LEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQ
LSEFIQTQYFD

Sequences:

>Translated_331_residues
MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLLDAIMPFCGNALRLGVTGTPGAGKSTFLEAFGMLLIR
EGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYESALHILRHKYDEWQPRVLTCSA
LEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQ
LSEFIQTQYFD
>Mature_331_residues
MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLLDAIMPFCGNALRLGVTGTPGAGKSTFLEAFGMLLIR
EGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYESALHILRHKYDEWQPRVLTCSA
LEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQ
LSEFIQTQYFD

Specific function: Phosphorylates the AO and LAO periplasmic-binding proteins [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=287, Percent_Identity=47.0383275261324, Blast_Score=263, Evalue=1e-70,
Organism=Escherichia coli, GI1789285, Length=331, Percent_Identity=98.4894259818731, Blast_Score=674, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994271, Length=297, Percent_Identity=41.7508417508418, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71994275, Length=235, Percent_Identity=44.6808510638298, Blast_Score=224, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR016121 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36610; Mature: 36610

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLLDAIMPFCGNALRLGVT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCC
GTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIR
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQSETEVARMVDCFISLQIAGGG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCC
DDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYESALHILRHKYDEWQPRVLTCSA
CHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
LEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYY
HHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLLDAIMPFCGNALRLGVT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCC
GTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIR
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQSETEVARMVDCFISLQIAGGG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHEEEECCCC
DDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYESALHILRHKYDEWQPRVLTCSA
CHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
LEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYY
HHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9733684; 9278503 [H]