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The map label for this gene is bglA

Identifier: 218701610

GI number: 218701610

Start: 3470647

End: 3472086

Strand: Direct

Name: bglA

Synonym: ECIAI39_3317

Alternate gene names: 218701610

Gene position: 3470647-3472086 (Clockwise)

Preceding gene: 218701607

Following gene: 218701618

Centisome position: 67.63

GC content: 50.83

Gene sequence:

>1440_bases
ATGATAGTGAAAAAACTCACCTTACCGAAAGATTTCTTATGGGGCGGCGCAGTTGCCGCTCATCAGGTCGAAGGCGGCTG
GAACAAAGGCGGCAAAGGGCCGAGCATTTGTGACGTTCTGACCGGTGGCGCACACGGTGTGCCGCGCGAAATCACCAAAG
AAGTCTTGCCAGGCAAATACTATCCGAACCATGAAGCCGTTGATTTTTATGGTCACTACAAGGAGGACATCAAGCTATTT
GCCGAAATGGGCTTCAAATGTTTTCGTACTTCCATCGCCTGGACGCGCATTTTTCCAAAAGGCGATGAAGCTCAGCCAAA
CGAAGAAGGGCTGAAGTTCTACGATGATATGATCGATGAACTGCTGAAATACAACATCGAACCGGTGATCACCCTCTCCC
ACTTTGAAATGCCGCTGCATCTGGTGCAGCAATACGGTAGCTGGACCAACCGTAAAGTGGTTGATTTCTTTGTCCGTTTC
GCAGAAGTGGTATTTGAACGCTATAAGCATAAAGTCAAATACTGGATGACCTTCAACGAAATTAACAACCAGCGTAACTG
GCGTGCACCGCTGTTCGGTTACTGCTGCTCCGGCGTGGTGTATACCGAGCATGATAACCCGGAAGAGACGATGTACCAGG
TGCTGCATCACCAGTTTGTCGCCAGCGCCCTGGCGGTGAAAGCCGCGCGTCGCATTAACCCGGAAATGAAAGTCGGCTGT
ATGCTGGCGATGGTGCCGCTTTACCCTTACTCCTGTAATCCGGACGATGTGATGTTCGCTCAGGAGTCGATGCGCGAACG
CTACGTCTTTACCGATGTGCAGCTACGCGGCTATTACCCGTCCTATGTGTTGAACGAGTGGGAGCGTCGCGGATTTAACA
TCAAAATGGAAGATGGCGATCTGGATGTACTGCGTGAAGGCACCTGCGATTATCTTGGTTTCAGCTATTACATGACCAAC
GCAGTGAAGGCCGAAGGCGGTACCGGCGATGCGATCTCTGGTTTTGAAGGCAGCGTACCGAATCCGTATGTTAAAGCGTC
TGACTGGGGCTGGCAGATTGATCCTGTGGGTCTGCGTTACGCACTTTGCGAACTGTATGAGCGTTATCAGAAGCCGCTGT
TTATTGTCGAAAACGGTTTTGGCGCTTATGACAAAGTGGAAGAAGATGGCAGCATCAACGACGACTACCGCATTGACTAC
CTGCGCGCCCATATTGAAGAGATGAAAAAAGCGGTGACTTACGATGGCGTGGATCTGATGGGCTACACACCGTGGGGCTG
CATCGGCTGTGTGTCGTTTACCACCGGGCAGTACAGCAAACGCTACGGCTTTATCTATGTGAATAAACATGACGACGGTA
CTGGCGATATGTCGCGTTCACGTAAGAAGAGCTTTAGCTGGTACAAAGAGGTGATTGCCAGCAACGGCGAGAATCTGTAA

Upstream 100 bases:

>100_bases
TTACGCCCAGCCAGAATGTCATCCTGGAAACGTTGAAAAAAAGTGATGTCGTTTGGCTGCATGGTACTATTTCCTGTAAG
AATTGACTCATCTGGAGCCT

Downstream 100 bases:

>100_bases
TTAGCCGATGTGCCTGATGTGCTCCGCTCATCAGGCCTGGCACTCTTTTAATATATTGAGCTCGCAATATTTTATATTAC
GCCTCAGCCGAAACACACAA

Product: 6-phospho-beta-glucosidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMIDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIGCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFSWYKEVIASNGENL

Sequences:

>Translated_479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMIDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIGCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFSWYKEVIASNGENL
>Mature_479_residues
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMIDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIGCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFSWYKEVIASNGENL

Specific function: Unknown

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=503, Percent_Identity=30.2186878727634, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI32481206, Length=491, Percent_Identity=29.5315682281059, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI13273313, Length=491, Percent_Identity=26.4765784114053, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=28.1893004115226, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI28376633, Length=484, Percent_Identity=26.6528925619835, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI190360571, Length=109, Percent_Identity=32.1100917431193, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367174, Length=479, Percent_Identity=98.7473903966597, Blast_Score=992, Evalue=0.0,
Organism=Escherichia coli, GI1789070, Length=478, Percent_Identity=50.836820083682, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI2367270, Length=474, Percent_Identity=50.6329113924051, Blast_Score=467, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=28.7784679089027, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=27.0491803278689, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI21356577, Length=508, Percent_Identity=27.1653543307087, Blast_Score=162, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55186; Mature: 55186

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKY
CCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCC
YPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMIDE
CCCCCCEEHHCCHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
LLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNE
HHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEHH
INNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
HCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGD
HHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHCCCEEEECCCC
LDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRY
HHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIEEMKKAVTYDGVDLM
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEC
GYTPWGCIGCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFSWYKEVIASNGENL
CCCCCHHHHHEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKY
CCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCC
YPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDDMIDE
CCCCCCEEHHCCHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
LLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAEVVFERYKHKVKYWMTFNE
HHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEHH
INNQRNWRAPLFGYCCSGVVYTEHDNPEETMYQVLHHQFVASALAVKAARRINPEMKVGC
HCCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDGD
HHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHCCCEEEECCCC
LDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRY
HHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCEEECCHHHHH
ALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDYLRAHIEEMKKAVTYDGVDLM
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEC
GYTPWGCIGCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFSWYKEVIASNGENL
CCCCCHHHHHEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]