Click here to switch to the map view.

The map label for this gene is luxS

Identifier: 218701182

GI number: 218701182

Start: 2985069

End: 2985584

Strand: Reverse

Name: luxS

Synonym: ECIAI39_2877

Alternate gene names: 218701182

Gene position: 2985584-2985069 (Counterclockwise)

Preceding gene: 218701183

Following gene: 218701179

Centisome position: 58.18

GC content: 52.13

Gene sequence:

>516_bases
ATGCCGTTGTTAGATAGCTTCACAGTCGATCATACCCGGATGGAAGCGCCTGCAGTTCGGGTGGCGAAAACAATGAACAC
CCCGCATGGCGACGCAATCACCGTGTTCGATCTGCGCTTCTGCGTGCCGAACAAAGAAGTGATGCCAGAAAGAGGGATCC
ATACCCTGGAGCACCTGTTTGCTGGTTTTATGCGTAACCATCTTAACGGTAATGGCGTAGAGATTATCGATATCTCGCCA
ATGGGCTGCCGCACCGGTTTTTATATGAGTCTGATTGGTACGCCAGATGAGCAGCGTGTCGCTGATGCCTGGAAAGCTGC
AATGGAAGACGTGCTGAAAGTGCAGGATCAGAATCAGATCCCGGAACTGAACGTCTACCAGTGTGGCACTTACCAGATGC
ACTCGTTGCAGGAAGCGCAGGGTATTGCGCGTAACATTCTGGAACGTGACGTGCGCATCAACAGCAACGAAGAACTGGCG
CTGCCGAAAGAGAAGTTGCAGGAACTGCACATCTAG

Upstream 100 bases:

>100_bases
TCAGGGATGATGATAACAAATGCGCGTCTTTCATATACTCAGACTCGCCTGGGAAGAAAGAGTTCAGAAAATTTTTAAAA
AAATTACCGGAGGTGGCTAA

Downstream 100 bases:

>100_bases
TCAGTAAACTATCTTCACAATTAATTGAAAAAAGCCAGTTCAAATGAACTGGCTTAGTTGTACTTAGTGCGCACCGCCTC
CGCCGCCACCTGCGCCAAAG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELA
LPKEKLQELHI

Sequences:

>Translated_171_residues
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELA
LPKEKLQELHI
>Mature_170_residues
PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPM
GCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELAL
PKEKLQELHI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=98.8304093567251, Blast_Score=355, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19386; Mature: 19254

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLF
CCCCCCCCCCHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQI
HHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELALPKEKLQELHI
CCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLF
CCCCCCCCCHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
AGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQI
HHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNVYQCGTYQMHSLQEAQGIARNILERDVRINSNEELALPKEKLQELHI
CCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA