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The map label for this gene is yfjD

Identifier: 218701124

GI number: 218701124

Start: 2926058

End: 2927254

Strand: Direct

Name: yfjD

Synonym: ECIAI39_2816

Alternate gene names: 218701124

Gene position: 2926058-2927254 (Clockwise)

Preceding gene: 218701123

Following gene: 218701126

Centisome position: 57.02

GC content: 51.38

Gene sequence:

>1197_bases
ATGACCCTCAACCGCTATCGTCTGCGACATATGGCGAAACAGGGTAATCGCTCGGCCAAACGCGTCGAAAAATTGCTGCG
TAAGCCAGACCGCCTGATAAGCCTGGTGTTAATCGGCAATAACCTGGTCAATATTCTTGCCTCCGCGCTCGGCACTATTG
TTGGGATGCGTTTGTACGGCGATGCGGGCGTGGCAATTGCAACTGGTGTGCTGACTTTTGTCGTACTGGTTTTTGCTGAG
GTATTGCCGAAAACCATTGCCGCGCTGTACCCGGAAAAAGTCGCCTATCCAAGTAGTTTTCTGCTGGCGCCGCTGCAAAT
TTTGATGATGCCGCTGGTCTGGTTGCTGAACGCTATTACCCGCATGTTAATGCGCATGATGGGCATCAAAACCGATATCG
TGGTTAGTGGCTCTTTAAGCAAAGAAGAATTACGCACCATTGTGCACGAATCGCGGTCACAAATTTCCCGTCGCAATCAG
GATATGCTGTTGTCAGTACTCGATCTGGAAAAGATGACCGTCGATGACATCATGGTGCCGCGCAGTGAAATTATCGGTAT
TGATATCAACGATGACTGGAAATCGATTCTGCGCCAACTCTCCCACTCACCTCACGGGCGCATCGTGCTCTACCGTGATT
CGCTGGACGACGCCATCAGTATGCTGCGTGTGCGTGAAGCCTGGCGACTCATGTCGGAGAAAAAAGAGTTCACCAAAGAA
ACCATGCTACGCGCCGCGGACGAGATCTATTTTGTCCCGGAGGGTACGCCGCTCAGCACACAGTTGGTAAAGTTTCAGCG
CAACAAAAAGAAAGTCGGCCTGGTCGTCAACGAGTATGGAGACATTCAGGGGCTGGTGACGGTCGAAGATATTCTCGAAG
AGATTGTCGGCGATTTCACCACGTCGATGTCGCCAACACTTGCCGAAGAGGTCACGCCGCAAAACGACGGGTCGGTGATT
ATCGATGGCACCGCCAACGTGCGAGAAATTAACAAAGCCTTTAACTGGCATCTACCGGAAGATGATGCTCGTACTGTTAA
CGGCGTCATTCTGGAAGCGCTGGAGGAGATCCCGGTAGCAGGCACCCGCGTGCGTATTGGCGAGTACGATATCGATATTC
TCGACGTACAGGACAATATGATTAAGCAAGTAAAAGTTTTTCCTGTAAAACCGCTGCGCGAGAGTGTGGCGGAGTAA

Upstream 100 bases:

>100_bases
GGAGTTTCCCCTGGAACACATTTCTACTACTACGTTGATCATTATTCTGATCATCATGGTGGTCATTTCAGCCTATTTTT
CCGGGTCCGAAACCGGAATG

Downstream 100 bases:

>100_bases
CGAAAACGGCCCGGCATTCGCATGCTGGGCCGTGATTTATTACGAAAGCTGAAATTAAGCTTTTGCTTTCGCTACAGTAA
CCATCGCCGCACGAATTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLTFVVLVFAE
VLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIKTDIVVSGSLSKEELRTIVHESRSQISRRNQ
DMLLSVLDLEKMTVDDIMVPRSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKE
TMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVI
IDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGTRVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE

Sequences:

>Translated_398_residues
MTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLTFVVLVFAE
VLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIKTDIVVSGSLSKEELRTIVHESRSQISRRNQ
DMLLSVLDLEKMTVDDIMVPRSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKE
TMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVI
IDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGTRVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE
>Mature_397_residues
TLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLTFVVLVFAEV
LPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIKTDIVVSGSLSKEELRTIVHESRSQISRRNQD
MLLSVLDLEKMTVDDIMVPRSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKET
MLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMSPTLAEEVTPQNDGSVII
DGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGTRVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE

Specific function: Unknown

COG id: COG4536

COG function: function code P; Putative Mg2+ and Co2+ transporter CorB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=360, Percent_Identity=26.1111111111111, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI94681046, Length=315, Percent_Identity=26.031746031746, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40068053, Length=315, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI40068055, Length=315, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI145693175, Length=398, Percent_Identity=100, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI1790664, Length=407, Percent_Identity=22.1130221130221, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786879, Length=250, Percent_Identity=26.4, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082033, Length=277, Percent_Identity=27.4368231046931, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788119, Length=235, Percent_Identity=29.7872340425532, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFJD_ECOLI (P37908)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X07863
- RefSeq:   AP_003193.1
- RefSeq:   YP_026171.3
- ProteinModelPortal:   P37908
- DIP:   DIP-12070N
- MINT:   MINT-1274766
- STRING:   P37908
- EnsemblBacteria:   EBESCT00000004195
- EnsemblBacteria:   EBESCT00000018228
- GeneID:   2847739
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5415
- KEGG:   eco:b4461
- EchoBASE:   EB2336
- EcoGene:   EG12442
- eggNOG:   COG4536
- GeneTree:   EBGT00050000010862
- HOGENOM:   HBG673071
- OMA:   TALHNQD
- ProtClustDB:   PRK11573
- BioCyc:   EcoCyc:G7356-MONOMER
- Genevestigator:   P37908
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 44791; Mature: 44660

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x24325688)-; HASH(0x2387f470)-; HASH(0x24062218)-; HASH(0x23b3820c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYG
CCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHEEEHEECCHHHHHHHHHHHHHHHHHHCC
DAGVAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RMLMRMMGIKTDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVP
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKE
HHHEEEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFT
HHHHHHHCEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHH
TSMSPTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVA
CCCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
GTRVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE
CCEEEECCCCEEEEECCHHHHHHHHCCCCCHHHHHHCH
>Mature Secondary Structure 
TLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYG
CCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHEEEHEECCHHHHHHHHHHHHHHHHHHCC
DAGVAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RMLMRMMGIKTDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVP
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
RSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKE
HHHEEEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFT
HHHHHHHCEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHH
TSMSPTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVA
CCCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
GTRVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE
CCEEEECCCCEEEEECCHHHHHHHHCCCCCHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 3045760