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The map label for this gene is yeeJ [C]

Identifier: 218701019

GI number: 218701019

Start: 2807069

End: 2809273

Strand: Reverse

Name: yeeJ [C]

Synonym: ECIAI39_2710

Alternate gene names: 218701019

Gene position: 2809273-2807069 (Counterclockwise)

Preceding gene: 218701020

Following gene: 218701018

Centisome position: 54.74

GC content: 47.62

Gene sequence:

>2205_bases
TTGACTTTATCATTGTCACAGGAAAAGTGCATGCTGCGATGGACACGCTGTATTATGCTAACATTTATCTCTGGGGCTGC
TTTTGCGGCTCCAGAGATAAATGTTGAGCATAAAGAATCATTACCTGATTTAGGTAGTCAGGCCGCACAACAAGAAGAAC
AAACCAACAAGGGGAAATCGCTAAAAGAGCGTGGTGCCGATTACGTCATTAACTCCGCTACGCAAGGGTTTGAAAACCTG
ACACCCGAGGCGCTGGAGTCCCAGGCCAGAAGCTATCTGCAAAGTCAAATTACCTCTACGACACAATCTTATATTGAGGA
TACACTCTCCCCCTACGGTAAGGTTCGAACGAATCTTTCTCTTGGCCAGGGCGGCGATCTGGATGGCAGTTCCATCGACT
ATTTTGTTCCCTGGTATGATAATCAAACTACTGTTTATTTCAGCCAATTTTCTGCACAACGAAAAGAAGAGCGTACGATC
GGGAATATTGGGCTTGGTGTAAGACATAATTTTGATAAATGGTTGTTGGGTGGAAATATATTTTATGATTATGATTTTAC
CCGTGGGCATCGCCGTTTAGGTTTAGGTGCCGAAGCGTGGACTGATTATTTAAAATTCTCTGGCAACTATTATCACCCGC
TTTCTGACTGGAAAGACTCCGAAGATTTTGATTTTTATGAGGAGCGTCCTGCGCGCGGCTGGGATATTCGCGCCGAAGCC
TGGCTTCCCGCTTATCCGCAGCTTGGTGGTAAAATTGTTTTCGAACAGTATTACGGTAATGAAGTCGCGCTTTTTGGCAC
TGATAATCTGGAGAAAGATCCCTTCGCTGTCACGCTGGGTGTGAAATACCAGCCCGTTCCGCTCATTGCTGTCGGTACAG
ATTTCAAAGCTGGCACTGGCGATAATACCGATCTTTCTGTTAACGCAACGCTTAATTATCAGTTTGGCGTCCCGCTCAAA
GACCAGCTTGATCCTGACAAAGTGAGCGCGGCTCACTCGCTTATGGGCAGCCGTCATGACTTTGTTGAACGTAACAACTT
TATTGTTCTGGAATACAAAGAAAAAGATCCCCTCGACGTCACTTTGTGGCTGAAAGCCGACGCCACGAATGAACATCCCG
AGTGCGTGATTAAAGATACGCCTGAAGAAGCTATCGGGCTGGAAAAATGTAAATGGACCATTAACGCGCTCATTAACCAT
CACTACAAAATCGTCGCTGCCTCCTGGCAGGCGAAAAACAATGCTGCACGTACGCTGGTGATGCCGGTTATCAAAGAAAA
CACGCTTACCGAAGGTAACAACAACCACTGGAATCTGGTGCTGCCTGCCTGGCAGTACAGTTCTGATAAAGCCGAACAAG
AAAAACTCAATACCTGGCGGGTTCGTCTGGCGCTGGAAGATGAAAAAGGTAATCGACAGAATTCCGGCGTGGTGGAAATC
ACCGTTCAGCAGGATCGCAAAATTGAGCTCATCGTTAACAACATCGCCGATGTACCAGATGAGAACAATCACAGTCATGA
AGCCAGCGCACAGGCCGATGGTGTAGATGGTGTGGTGATGGATCTCGATATTACTGATAGCTTTGGCGACAACACTGACC
GCAACGGTAATGTCTTGCCGCAGGATAATCTCAACCCGCAGTTGTTTGACGCCAACGATAAAAAAGTGACGCTGACGAAT
AAACCCTGCACTACCGAGACTCCCTGTGTCTTTATCGCCAAACAAGATAAAGAAAAGGGGACCGTTACGCTCTCCAGTAC
ATTGCCTGGCACCTTCCGTTGGAAGGCGAAAGCCGCTCCCTATGATGACAGTAACTATGTTGACGTAACGTTCCTGGGTT
CTGACATCGGCGGGCTGAATGCCTTTATCTATCGTGTTGGTGCGGCTAAGCCCGTGAATCTTATCGGCAATAAAGAGCCG
TTGCCTCTCAATAGCAGCTATCGCTTTGTGTTGTGGCGTGACGCTAACAAAGACGGCGTGTTCCAGCTATCAGAGAAACT
CACTGAAGAGGAGATGAAACAGTATGACTATCAGTGGGAATTCACGGGACATAGCGTGAATGGCAATACCGGTGCGCAAG
CCAATACCACTAACGCCGATATAGAGATCCCGGCAACGAACAAGGACGCGGCAACGAAGTTTAGTGCCCAGGTAACCGAT
GGCGTGCAGGGATACGGTTTGCAGGTCAATTACAGCAAGAAATAG

Upstream 100 bases:

>100_bases
TACAATTGAGTGAGATCACTAATTTAAATAATTAAGAATATATTTATTCTTTATGGCATGCCTTTCTGAATAATCAGGGA
TACAATATTAAAGCTTATTT

Downstream 100 bases:

>100_bases
GATCAGCGCCATGGCTGATCGGGCCACCGCTGAATGTTAACCAAGGAGAGTGTTTATGAAACCTCATATGAAACGTGGCC
TGACAAGAGTCGCGCTGGCA

Product: putative intimin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MTLSLSQEKCMLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENL
TPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEERTI
GNIGLGVRHNFDKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEA
WLPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLK
DQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINH
HYKIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEI
TVQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTN
KPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEP
LPLNSSYRFVLWRDANKDGVFQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTD
GVQGYGLQVNYSKK

Sequences:

>Translated_734_residues
MTLSLSQEKCMLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENL
TPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEERTI
GNIGLGVRHNFDKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEA
WLPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLK
DQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINH
HYKIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEI
TVQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTN
KPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEP
LPLNSSYRFVLWRDANKDGVFQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTD
GVQGYGLQVNYSKK
>Mature_733_residues
TLSLSQEKCMLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKSLKERGADYVINSATQGFENLT
PEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEERTIG
NIGLGVRHNFDKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAW
LPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKD
QLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHH
YKIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEIT
VQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNK
PCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPL
PLNSSYRFVLWRDANKDGVFQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTDG
VQGYGLQVNYSKK

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=407, Percent_Identity=35.3808353808354, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI145693120, Length=444, Percent_Identity=31.5315315315315, Blast_Score=202, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 82221; Mature: 82090

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSLSQEKCMLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKS
CCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCC
LKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLS
HHHCCCCEEEECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEE
LGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEERTIGNIGLGVRHNFDKWLLGGNI
CCCCCCCCCCCEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCEECCCCCEEECCEE
FYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEA
EEEECCCCCCCEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECC
WLPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTG
CCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCC
DNTDLSVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDV
CCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEE
TLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLV
EEEEEECCCCCCCCEEEECCCHHHHCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
MPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEI
EEEECCCCCCCCCCCEEEEEEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCCCCCEEEE
TVQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLP
EECCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
QDNLNPQLFDANDKKVTLTNKPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAP
CCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCC
YDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFVLWRDANKDGV
CCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCH
FQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTD
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEECC
GVQGYGLQVNYSKK
CCCCCEEEEEECCC
>Mature Secondary Structure 
TLSLSQEKCMLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQTNKGKS
CCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCC
LKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPYGKVRTNLS
HHHCCCCEEEECHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEE
LGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEERTIGNIGLGVRHNFDKWLLGGNI
CCCCCCCCCCCEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCEECCCCCEEECCEE
FYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEA
EEEECCCCCCCEECCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECC
WLPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPVPLIAVGTDFKAGTG
CCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECEECCEEEEEECCCCCCCCC
DNTDLSVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLDV
CCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCEE
TLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHYKIVAASWQAKNNAARTLV
EEEEEECCCCCCCCEEEECCCHHHHCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
MPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWRVRLALEDEKGNRQNSGVVEI
EEEECCCCCCCCCCCEEEEEEEEEECCCCCHHHHCCCEEEEEEEEECCCCCCCCCCEEEE
TVQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGVVMDLDITDSFGDNTDRNGNVLP
EECCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
QDNLNPQLFDANDKKVTLTNKPCTTETPCVFIAKQDKEKGTVTLSSTLPGTFRWKAKAAP
CCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEEEECCC
YDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNLIGNKEPLPLNSSYRFVLWRDANKDGV
CCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEEEECCCCCCH
FQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGAQANTTNADIEIPATNKDAATKFSAQVTD
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEECC
GVQGYGLQVNYSKK
CCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]