Click here to switch to the map view.

The map label for this gene is eutG

Identifier: 218700909

GI number: 218700909

Start: 2685096

End: 2686283

Strand: Reverse

Name: eutG

Synonym: ECIAI39_2590

Alternate gene names: 218700909

Gene position: 2686283-2685096 (Counterclockwise)

Preceding gene: 218700910

Following gene: 218700908

Centisome position: 52.34

GC content: 58.25

Gene sequence:

>1188_bases
ATGCAAAATGAATTGCAAACGGCGCTTTTTCAGGCATTCGATACCCTGAATTTGCAGCGGGTGAAAACATTTAGTGTTCC
ACCGGTGACGCTTTGCGGTCTGGGGGCCGTGAGCAGTTGCGGACAGCAAGCGCAATCGCGTGGGCTGAAACATCTGTTCG
TGATGGCAGACAGCTTTTTGCATCAGGCCGGGATGACCGCCGGGCTGACGCGTAGCCTGGCCGTTAAAGGTATCGCCATG
ACGCTCTGGCCATGTCCGGTGGGCGAACCATGCATCACCGACGTGTGTGCAGCCGTGGCGCAGTTGCGTGAATCAGGCTG
TGACGGGGTGATTGCGTTTGGCGGCGGCTCGGTGCTGGATGCAGCAAAAGCCGTGGCGTTGCTGGTGACGAACCCGGATA
GCACGCTGGCAGAAATGTCAGAAACCAGCGTTCTGCAACCGCGCCTGCCGTTGATTGCCATTCCAACGACCGCCGGAACC
GGCTCTGAAACGACTAACGTGACGGTGATTATCGATGCGGTAAGCGGGCGCAAACAGGTGTTAGCCCATGCCTCGCTGAT
GCCGGATGTCGCGATTCTCGACGCTGCGCTAACCGAAGGCGTGCCGTCGCATGTCACGGCGATGACTGGCATTGATGCGT
TAACCCATGCCATTGAAGCGTACAGCGCGCTGAACGCCACACCGTTTACCGACAGTCTGGCGATTGGTGCCATTGCGATG
ATTGGCAAATCGCTGCCGAAAGCGGTGGGCTACGGTCATGACCTTGCCGCGCGCGAGAGCATGTTGCTGGCTTCATGTAT
GGCGGGAATGGCGTTTTCCAGTGCGGGGCTTGGGTTGTGCCACGCGATGGCGCATCAGCCGGGGGCGGCGCTGCATATTC
CGCACGGTCTGGCGAACGCTATGTTGCTGCCAACGGTGATGGAATTTAACCGGATGGTTTGTCGTGATCGGTTTAGTCAG
ATTGGCCGGGCACTGCGAACTAAAAAATCCGACGATCGTGACGCTATTAACGCGGTAAGTGAGTTGATTGCGGAAGTCGG
GATTGGTAAACGACTGGGCGATGTTGGTGCGACATCGGTGCATTACGGTGCATGGGCGCAGGCCGCGCTGGAAGATATTT
GTCTGCGCAGCAACCCGCGTACCGCCAGCCTGGAGCAGATTGTCGGCCTGTACGCAGCGGCGCAATAA

Upstream 100 bases:

>100_bases
AAACAATTTCCGGCGTTACAGGTGCATTTACCGCAGCACAGTTTGTTTATGACCCCGCTGGCAATCGCCAGTAGTGGGCG
AGAGAAAGCGGAGGGGCTAT

Downstream 100 bases:

>100_bases
ATGCCGGATGCGACGCTTGCCGCGTCTGATCCGGCCTTCGGGATTGCACATGTAGGGCGGATAAGACGTTCACGCCGCAT
CCGCCAATAAATAACAACTA

Product: putative alcohol dehydrogenase in ethanolamine utilization; ethanolaminosome

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQAQSRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSVHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ

Sequences:

>Translated_395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQAQSRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSVHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
>Mature_395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQAQSRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSVHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=407, Percent_Identity=26.044226044226, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI87082107, Length=395, Percent_Identity=98.2278481012658, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=37.037037037037, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=39.7849462365591, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1787493, Length=381, Percent_Identity=32.0209973753281, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789386, Length=284, Percent_Identity=26.4084507042254, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=323, Percent_Identity=28.1733746130031, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=380, Percent_Identity=33.6842105263158, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24657991, Length=404, Percent_Identity=27.7227722772277, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 40972; Mature: 40972

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQAQSRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCC
HYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGLGAVSSCGQQAQSRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCC
HYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]