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The map label for this gene is ccmF

Identifier: 218700665

GI number: 218700665

Start: 2405740

End: 2407683

Strand: Reverse

Name: ccmF

Synonym: ECIAI39_2334

Alternate gene names: 218700665

Gene position: 2407683-2405740 (Counterclockwise)

Preceding gene: 218700666

Following gene: 218700664

Centisome position: 46.91

GC content: 57.41

Gene sequence:

>1944_bases
ATGATGCCGGAAATTGGTAACGGACTGCTGTGTCTGGCGCTAGGAGTTGCGCTGCTGCTGTCCGTGTATCCGCTATGGGG
CGTAGCGCGCGGAGATGCGCGCATGATGGCGTCTTCCCGCTTGTTTGCCTGGCTGCTGTTTATGTCTGTGGCTGGCGCAT
TTCTGGTACTGGTCAATGCCTTCGTGGTCAACGACTTCACCGTCACCTATGTTGCCAGCAACTCCAATACCCAGCTTCCG
GTGTGGTATCGCGTGGCGGCTACCTGGGGCGCGCATGAAGGCTCGCTCCTGCTGTGGGTGCTGCTGATGAGCGGCTGGAC
CTTTGCGGTAGCGATTTTTAGTCAGCGTATTCCGCTGGATATTGTGGCCCGCGTACTGGCGATAATGGGGATGGTCAGCG
TCGGCTTTTTGCTGTTCATTCTCTTTACCTCTAACCCGTTCTCACGCACGTTGCCGAACTTCCCGATTGAAGGTCGCGAT
CTTAACCCGCTGTTACAGGATCCGGGGCTGATCTTCCATCCGCCTCTGCTTTATATGGGGTACGTCGGCTTCTCGGTGGC
GTTTGCTTTTGCCATTGCTTCTTTGTTGAGCGGGCGTCTGGACAGCACTTATGCGCGTTTTACTCGTCCGTGGACGCTGG
CAGCGTGGATCTTCCTGACGCTCGGCATTGTGCTCGGTTCCGCATGGGCCTATTACGAACTCGGCTGGGGCGGCTGGTGG
TTCTGGGATCCGGTAGAAAACGCCTCGTTTATGCCGTGGCTGGTGGGGACTGCGCTGATGCACTCACTGGCGGTCACTGA
ACAACGCGCCAGCTTCAAAGCGTGGACATTACTGCTGGCAATCAGTGCCTTCTCGTTGTGTCTGCTGGGGACTTTCCTGG
TGCGTTCCGGCGTGCTGGTATCGGTACACGCGTTTGCCTCTGATCCGGCACGCGGTATGTTTATCCTCGCCTTTATGGTA
CTGGTGATTGGTGGTTCGCTGCTGCTGTTTGCCGCGCGTGGACACAAAGTTCGCTCACGCGTAAACAATGCGCTGTGGTC
GCGGGAATCTCTGCTGTTAGCGAACAACGTTTTGCTGGTCGCCGCGATGCTGGTGGTGTTGCTGGGGACGCTGCTGCCGC
TGGTGCACAAGCAACTGGGACTGGGCAGTATTTCGATTGGCGAACCGTTCTTCAACACCATGTTTACCTGGCTGATGGTG
CCGTTTGCGCTGCTGCTTGGTGTCGGTCCTCTGGTGCGCTGGGGGCGCGATCGCCCACGTAAAATCCGCAATTTGTTGAT
TATCGCCTTCATCTCTACGCTGGTGCTGTCGCTGCTGTTGCCGTGGCTGTTCGAAAGCAAAGTGGTGGCGATGACGGTGC
TCGGCCTGGCAATGGCCTGCTGGATTGAGGTGCTGGCAATTGCGGAAGCTGCGCTGCGTATTTCACGCGGCACGAAAACC
ACCTTCAGTTATTGGGGAATGGTGGCGGCTCACCTGGGGCTGGCAGTGACAATTGTTGGTATTGCCTTTAGCCAGAACTA
TAGCGTTGAGCGTGATGTGCGCATGAAGTCCGGCGATAGTGTCGATATTCATGAATATCGCTTCACCTTCCGTGATGTCA
AAGAGGTGACTGGCCCGAACTGGCGTGGCGGTGTGGCGACTATCGGCGTAACGCGCGATGGCAAGCCGGAAACGGTGCTG
TATGCGGAAAAACGTTATTACAACACTGCCGGGTCGATGATGACCGAAGCGGCGATTGACGGCGGCATCACGCGTGACCT
GTACGCCGCGCTCGGTGAAGAGCTGGAAAACGGCGCGTGGGCCGTGCGTCTTTACTACAAACCGTTTGTTCGCTGGATTT
GGGCGGGCGGGCTGATGATGGCATTGGGCGGGCTGCTGTGCCTGTTTGATCCTCGCTATCGTAAGCGCGTGAACCCGCAG
AAAACTGCGCCGGAGGCTGTATGA

Upstream 100 bases:

>100_bases
TGCTGGCGAAACACGATGAAAACTACACGCCGCCAGAAGTTGAGAAAGCGATGGAAGCCAATCACCGTCGCCCGGCGAGT
GTTTATAAGGACCCAGCATC

Downstream 100 bases:

>100_bases
AGCGCAAAGTATTGTTAATTCCGTTGATTATCTTCCTGGCGATTGCCACGGCGCTACTGTGGCAGCTGGCGCGTAATGCC
GAAGGGGATGATCCGACCAA

Product: heme lyase CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MMPEIGNGLLCLALGVALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIEVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV

Sequences:

>Translated_647_residues
MMPEIGNGLLCLALGVALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIEVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV
>Mature_647_residues
MMPEIGNGLLCLALGVALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIEVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=647, Percent_Identity=99.5363214837712, Blast_Score=1280, Evalue=0.0,
Organism=Escherichia coli, GI1790511, Length=581, Percent_Identity=38.5542168674699, Blast_Score=313, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71461; Mature: 71461

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPEIGNGLLCLALGVALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIEVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAV
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMPEIGNGLLCLALGVALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIEVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAV
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]