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The map label for this gene is ycaI

Identifier: 218700568

GI number: 218700568

Start: 2287601

End: 2289865

Strand: Reverse

Name: ycaI

Synonym: ECIAI39_2234

Alternate gene names: 218700568

Gene position: 2289865-2287601 (Counterclockwise)

Preceding gene: 218700569

Following gene: 218700567

Centisome position: 44.62

GC content: 50.29

Gene sequence:

>2265_bases
ATGAAAATAACGACAGTCGGCGTATGCATAATTTGCGGAATTTTTCCGTTGCTGGTTTTGCCCCAATTGCCTGGGACATT
AACCCTTGCGTTTCTGACTGTCTTCGCCTGCGTACTGGTATTTATCCCTTTTAAAGCCGTCCGTTATATCGCGCTGACGT
TGCTGTTTTTTCTTTGGGGCATATCAGCGGCAAAGCAAATTTTGTGGGCAGGAGAAACCTTAACTGGCGCGACGCAGGAT
GCAATAGTTGAGATCACTGCTACTGACGGCATGACCACTCATTACGGTCAAATCACTCATCTACAAAGTCGACGTATATT
CCCTGCGCCAGGCCTCGTGCTGTATGGCGAATATCTTCCGCAAGCGGTTTGTGCTGGACAACAATGGTCAATGAAACTCA
AAGTTCGTGCAGTTCATGGCCAACTTAATGATGGCGGCTTTGATAGCCAGCGTTATGCCATTGCCCAGCATCAGCCGCTG
ACCGGCCGCTTTCTGCAGGCAAGTGTCATTGAACCGAATTGTAGCTTGCGTGCACAGTATCTGGCGTCATTACAAACAAC
GCTGCAACCCTATCCGTGGAATGCGGTTATTCTTGGTTTAGGTATGGGGGAACGGTTATCCGTCCCCAAAGAAATCAAAA
ATATCATGCGCGATACTGGAACGGCGCATTTAATGGCGATATCGGGATTGCACATCGCTTTTGCGGCGTTGCTGGCTGCC
GGACTCATTCGCAGTGGACAAATTTTTCTGCCTGGGCGCTGGATCCACTGGCAAATGCCATTAATTGGCGGAATCTGCTG
TGCTGCTTTTTATGCCTGGCTGACGGGAATGCAACCTCCTGCATTGCGTACCGTGGTGGCGCTTGCTACGTGGGGAATGC
TTAAGTTAAGTGGGCGACAGTGGAGTGGCTGGGATGTATGGATATGTTGTCTGGCGGCAATTTTGCTGATGGATCCTGTT
GCCATTCTCTCGCAAAGTTTATGGCTCTCTGCCGCTGCGGTCGCGGCACTGATTTTTTGGTACCAGTGGTTTCCCTGTCC
GGCGTGGCAACTGCCGCCGGTATTGCGTGCAGTTGTTTCCCTCATCCATCTGCAACTGGGAATCACCCTCCTGCTTATGC
CCGTGCAAATCGTCATATTTCATGGCATTAGTCTGACCTCGTTTATTGCAAATCTATTTGCAATTCCCCTGGTGACATTT
ATCACGGTTCCGTTGATCCTCGCCGCTATGGTTGTGCATTTAAGCGGGCCGTTAATCCTGGAAGAGGGATTATGGTTTCT
TGCCGACCGGTCTTTGGCTTTACTTTTCTGGGGGTTAAAGAGTTTGCCGGAAGGGTGGATCAACATTGCTGAACGTTGGC
AATGGCTATCATTTTCCCCATGGTTCTTACTGGTGGTATGGCGATTAAACGCCTGGCGAACGTTGCCAGCAATGTGTGTG
GCTGGAGGCTTGCTGATGTGCTGGCCGCTGTGGCAAAAACCTCGACCTGACGAGTGGCAAGTGTACATGCTTGATGTCGG
GCAAGGGCTGGCAATGGTGATAGCCAGAAACGGCAAAGCGATTCTCTATGACACGGGACTGGCCTGGCCTGAAGGGGATA
GTGGGCAACAACTGATTATCCCCTGGCTCCACTGGCATAATCTTGAACCGGAAGGCGTTATTCTGAGTCATGAACATCTG
GATCACCGGGGAGGGCTGGACTCAATATTGCATACATGGCCGATGTTATGGATCAGAAGTCCGTTAAACTGGGAACACCA
TCAGCCCTGTGTGCGTGGCGAAGCGTGGCAATGGCAAGGATTGCGTTTCAGCGTGCACTGGCCTTTACAAGCTAGCAACG
ATAAAGGAAATAACCATTCCTGTGTGGTTAAGGTTGATGACGGGACGAATAGCATTCTTCTAACCGGTGATATTGAAGCC
CCCGCTGAACAAAAGATGCTAAGCCGTTACTGGCAGCAAGTGCAGGCAACATTGCTTCAGGTACCTCACCATGGCAGTAA
TACCTCATCATCGTTGCCATTAATTCAGCGAGTGAATGGAAAAGTGGCACTCGCATCGGCATCGCGCTATAACGCATGGC
GATTGCCCTCTAACAAAGTTAAGCATCGCTATCAACAGCAAGGATATCAATGGGGTGATACTCCACATCAGGGTCAAGTG
ACGGTCAATTTTTCAGCGCAAGGCTGGCGGATTAGCAGCCTCAGAGAGCAAATTTTACCTCGTTGGTATCATCAGTGGTT
TGGCGTGCCAGTGGATAACGGGTAG

Upstream 100 bases:

>100_bases
CTCTCGTTAAATTCTTCTGAACGTGCCTCGGGGAACGCAAAACTCCCACCAGACAACCGCTCAACAAAGTTGCACACTTT
CCATAAACAGGGAGGGGTGC

Downstream 100 bases:

>100_bases
AATATGCGGCTATTTCAACAAATGCTGGTTTTTTGAATGCATAACGACAAAGATCTCTCTACGTGGCAGACATTCCGCCG
ACTGTGGCCAACCATTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MKITTVGVCIICGIFPLLVLPQLPGTLTLAFLTVFACVLVFIPFKAVRYIALTLLFFLWGISAAKQILWAGETLTGATQD
AIVEITATDGMTTHYGQITHLQSRRIFPAPGLVLYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
AILSQSLWLSAAAVAALIFWYQWFPCPAWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLFAIPLVTF
ITVPLILAAMVVHLSGPLILEEGLWFLADRSLALLFWGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AGGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSVHWPLQASNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYQWGDTPHQGQV
TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG

Sequences:

>Translated_754_residues
MKITTVGVCIICGIFPLLVLPQLPGTLTLAFLTVFACVLVFIPFKAVRYIALTLLFFLWGISAAKQILWAGETLTGATQD
AIVEITATDGMTTHYGQITHLQSRRIFPAPGLVLYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
AILSQSLWLSAAAVAALIFWYQWFPCPAWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLFAIPLVTF
ITVPLILAAMVVHLSGPLILEEGLWFLADRSLALLFWGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AGGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSVHWPLQASNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYQWGDTPHQGQV
TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG
>Mature_754_residues
MKITTVGVCIICGIFPLLVLPQLPGTLTLAFLTVFACVLVFIPFKAVRYIALTLLFFLWGISAAKQILWAGETLTGATQD
AIVEITATDGMTTHYGQITHLQSRRIFPAPGLVLYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
AILSQSLWLSAAAVAALIFWYQWFPCPAWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLFAIPLVTF
ITVPLILAAMVVHLSGPLILEEGLWFLADRSLALLFWGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AGGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSVHWPLQASNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYQWGDTPHQGQV
TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG

Specific function: Unknown

COG id: COG0658

COG function: function code R; Predicted membrane metal-binding protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae Rec2 [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=754, Percent_Identity=96.684350132626, Blast_Score=1454, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 84492; Mature: 84492

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTVGVCIICGIFPLLVLPQLPGTLTLAFLTVFACVLVFIPFKAVRYIALTLLFFLWG
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQSRRIFPAPGLVLYGEYLP
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCCCEEEHHHHH
QAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPLTGRFLQASVIEPNCSLRAQY
HHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHH
LASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQ
HHHCCCCEEECCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCC
WSGWDVWICCLAAILLMDPVAILSQSLWLSAAAVAALIFWYQWFPCPAWQLPPVLRAVVS
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LIHLQLGITLLLMPVQIVIFHGISLTSFIANLFAIPLVTFITVPLILAAMVVHLSGPLIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
EEGLWFLADRSLALLFWGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
CCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
AGGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLII
HCCHHEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEEE
PWLHWHNLEPEGVILSHEHLDHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQG
EEHHHCCCCCCCEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC
LRFSVHWPLQASNDKGNNHSCVVKVDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQ
EEEEEEECEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYQWGDTPHQGQV
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCEE
TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKITTVGVCIICGIFPLLVLPQLPGTLTLAFLTVFACVLVFIPFKAVRYIALTLLFFLWG
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQSRRIFPAPGLVLYGEYLP
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCCCEEEHHHHH
QAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPLTGRFLQASVIEPNCSLRAQY
HHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHH
LASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
HHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHH
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQ
HHHCCCCEEECCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCC
WSGWDVWICCLAAILLMDPVAILSQSLWLSAAAVAALIFWYQWFPCPAWQLPPVLRAVVS
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LIHLQLGITLLLMPVQIVIFHGISLTSFIANLFAIPLVTFITVPLILAAMVVHLSGPLIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
EEGLWFLADRSLALLFWGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
CCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHH
AGGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLII
HCCHHEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEEE
PWLHWHNLEPEGVILSHEHLDHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQG
EEHHHCCCCCCCEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC
LRFSVHWPLQASNDKGNNHSCVVKVDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQ
EEEEEEECEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYQWGDTPHQGQV
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCEE
TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 8094880 [H]