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The map label for this gene is tonB [H]

Identifier: 218700325

GI number: 218700325

Start: 2041067

End: 2041447

Strand: Reverse

Name: tonB [H]

Synonym: ECIAI39_1983

Alternate gene names: 218700325

Gene position: 2041447-2041067 (Counterclockwise)

Preceding gene: 218700326

Following gene: 218700324

Centisome position: 39.78

GC content: 45.93

Gene sequence:

>381_bases
GTGGCAGTCTGGAACACAGGATATATTGTCAGAATAAGACCCGTAGGAATAAAAATGAAAAGACGCCTTTTACTACTTTT
TCTGTTATCTGTCCTGGCAGTGGGATGCTCGCAGCAAAAAGCTGATGAGCCCCGGCAATTAGTGACGGTGTATCCACGAT
ATCCGGAATATGCTGCAGCAAATTATATCAAGGGGCTGGTTGAGGTTAAGTTCGATATTGGTGCTGATGGGACTGTGACA
CGGATCGTTTTTCTCCGCTCAGAGCCTCATAATTTGTTTCGTGATGAAGTGGTGAAGGCCATGGCGAAATGGCGATTTGA
AAAGAATCGCCCCTGTCAGGGAGTGAAGAGACAATTTATCTTTACGCCGTCACGTCCTTGA

Upstream 100 bases:

>100_bases
TGGTGGAAGAAACAGGAAGCTGTATTACAGAAAGTGCTACTACTGTATCCCGATGCGATGTATGTAATGTGAGTCAGATA
ATGGCACAGGATGTGGTGAT

Downstream 100 bases:

>100_bases
TGCTTCCAGGTAGAGAGGGGCTGGAAGCAGGAGAAAAATGAAAGAGCCAGCGGTTATATTTTTGTCATGGCTGACGAGGA
ATGATGGAAGAAGGCGTTGT

Product: putative tonB-like membrane protein encoded within prophage

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MAVWNTGYIVRIRPVGIKMKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAANYIKGLVEVKFDIGADGTVT
RIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFIFTPSRP

Sequences:

>Translated_126_residues
MAVWNTGYIVRIRPVGIKMKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAANYIKGLVEVKFDIGADGTVT
RIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFIFTPSRP
>Mature_125_residues
AVWNTGYIVRIRPVGIKMKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAANYIKGLVEVKFDIGADGTVTR
IVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFIFTPSRP

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requirin

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=81, Percent_Identity=40.7407407407407, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 14584; Mature: 14453

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVWNTGYIVRIRPVGIKMKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAA
CCEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHH
NYIKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFI
HHHHHHHEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
FTPSRP
ECCCCC
>Mature Secondary Structure 
AVWNTGYIVRIRPVGIKMKRRLLLLFLLSVLAVGCSQQKADEPRQLVTVYPRYPEYAAA
CEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHH
NYIKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKAMAKWRFEKNRPCQGVKRQFI
HHHHHHHEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
FTPSRP
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8370545 [H]