| Definition | Escherichia coli IAI39 chromosome, complete genome. |
|---|---|
| Accession | NC_011750 |
| Length | 5,132,068 |
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The map label for this gene is yciK
Identifier: 218699980
GI number: 218699980
Start: 1679273
End: 1680031
Strand: Reverse
Name: yciK
Synonym: ECIAI39_1609
Alternate gene names: 218699980
Gene position: 1680031-1679273 (Counterclockwise)
Preceding gene: 218699981
Following gene: 218699979
Centisome position: 32.74
GC content: 52.57
Gene sequence:
>759_bases ATGCATTACCAGCCAAAACAAGATTTACTCAATGATCGCATTATCCTGGTGACGGGAGCCAGTGATGGTATTGGTCGTGA AGCCGCGATGACGTATGCACGCTATGGTGCGACAGTGATTCTGTTGGGCCGTAATGAAGAAAAATTACGTCAGGTAGCCA GCCACATAAACGAAGAAACTGGGCGTCAGCTACAGTGGTTTATTCTCGATTTGCTGACCTGCACGTCCGAAGATTGCCAA CAACTGGCACAGCGCATTGCCGTTAATTATCCGCGTCTGGATGGTGTTTTGCATAATGCCGGATTGCTCGGCGATGTTTG CCCAATGAGCGAACAAAATCCGCAGGTCTGGCAGGACGTCATGCAGGTCAACGTTAATGCCACCTTTATGCTCACCCAGG CACTGCTTCCTTTATTACTCAAATCGGACGCCGGTTCACTGGTCTTTACTTCATCAAGCGTTGGACGTCAGGGGCGTGCA AACTGGGGCGCTTATGCAGCGTCGAAATTTGCCACCGAAGGGATGATGCAGGTACTGGCCGATGAATATCAGCAGCGCCT GCGCGTCAACTGCATTAACCCAGGCGGTACGCGCACCGCAATGCGTGCCAGCGCCTTCCCGACCGAAGATCCACAGAAAC TTAAAACACCCGCTGATATCATGCCGCTCTACCTCTGGCTGATGGGCGATGACAGCCGCCGTAAAACCGGCATGACCTTT GACGCCCAACCGGGCCGTAAACCAGGAATTTCCCAATGA
Upstream 100 bases:
>100_bases CGCCCCAGGCTGATTGAAATGCCCTTCTGTTTCAGGCATAAAGCCCCAAAGTCATAAAGTACACTGGCAGCGCGACAGAC AACGTCGTTGAGGAGTAGCC
Downstream 100 bases:
>100_bases GTGATGAACGCTACCAACAGCGTCAGCAGCGAGTGAAAGAAAAAGTCGATGCTCGTGTGGCCCAGGCCCAGGATGAACGC GGTATTATCATCGTCTTTAC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQLQWFILDLLTCTSEDCQ QLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ
Sequences:
>Translated_252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQLQWFILDLLTCTSEDCQ QLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ >Mature_252_residues MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQLQWFILDLLTCTSEDCQ QLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF DAQPGRKPGISQ
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI142976729, Length=222, Percent_Identity=27.4774774774775, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=26.5060240963855, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=25.8333333333333, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=30.5825242718447, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7657478, Length=222, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=28.2828282828283, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=28.2828282828283, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=25.6038647342995, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=28.8617886178862, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI10190704, Length=189, Percent_Identity=24.3386243386243, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4557649, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI7705855, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI126723191, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=182, Percent_Identity=28.021978021978, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI59889578, Length=172, Percent_Identity=30.8139534883721, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=99.2063492063492, Blast_Score=520, Evalue=1e-149, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=32.5, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=30.1204819277108, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=28.4, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786701, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786812, Length=202, Percent_Identity=25.7425742574257, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=30, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560150, Length=211, Percent_Identity=28.436018957346, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17551412, Length=221, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI71997402, Length=250, Percent_Identity=28, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17544670, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17560220, Length=206, Percent_Identity=29.126213592233, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=30, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=212, Percent_Identity=27.3584905660377, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17570069, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562908, Length=208, Percent_Identity=32.6923076923077, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=26.9076305220884, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=24.904214559387, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562904, Length=217, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562990, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17560176, Length=175, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17562906, Length=232, Percent_Identity=27.1551724137931, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17561402, Length=239, Percent_Identity=23.8493723849372, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17568967, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17564282, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=29.9492385786802, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI72000259, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17563726, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=24.8995983935743, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17559104, Length=217, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538480, Length=213, Percent_Identity=25.3521126760563, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=26.8867924528302, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=214, Percent_Identity=29.4392523364486, Blast_Score=79, Evalue=6e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=25.4237288135593, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=226, Percent_Identity=28.3185840707965, Blast_Score=76, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6322226, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=8e-14, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=28.5140562248996, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=32.620320855615, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24640492, Length=182, Percent_Identity=29.6703296703297, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=28.3400809716599, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=34.6341463414634, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI281364892, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=29.1866028708134, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=27.34375, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI45553409, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24647948, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24647946, Length=217, Percent_Identity=27.1889400921659, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24584752, Length=230, Percent_Identity=29.5652173913043, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27950; Mature: 27950
Theoretical pI: Translated: 7.38; Mature: 7.38
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.4 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEET CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GRQLQWFILDLLTCTSEDCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDV CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLA HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF HHHHHHHEEEEECCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHEEECCCCCCCCCCEE DAQPGRKPGISQ CCCCCCCCCCCC >Mature Secondary Structure MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEET CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH GRQLQWFILDLLTCTSEDCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDV CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH MQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLA HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH DEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF HHHHHHHEEEEECCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHEEECCCCCCCCCCEE DAQPGRKPGISQ CCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9097039; 9278503; 1885549 [H]