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The map label for this gene is ychM

Identifier: 218699913

GI number: 218699913

Start: 1610679

End: 1612358

Strand: Reverse

Name: ychM

Synonym: ECIAI39_1542

Alternate gene names: 218699913

Gene position: 1612358-1610679 (Counterclockwise)

Preceding gene: 218699914

Following gene: 218699911

Centisome position: 31.42

GC content: 54.46

Gene sequence:

>1680_bases
GTGAACAAAATATTTTCCTCACATGTGATGCCTTTCCGCGCTCTGATCGACGCTTGCTGGAAAGAAAAATATACTGCCGC
ACGGTTTACCCGTGACCTAATTGCCGGGATAACCGTCGGGATTATTGCTATCCCGCTGGCAATGGCGTTGGCTATTGGTA
GTGGTGTGGCACCCCAGTACGGTTTATATACTGCAGCCGTTGCGGGGATTGTCATTGCTCTGACGGGTGGGTCACGCTTT
AGCGTTTCCGGTCCGACTGCGGCATTTGTGGTAATTCTCTATCCCGTTTCGCAACAGTTTGGACTGGCAGGACTGCTGGT
TGCGACCTTGCTGTCGGGGGTCTTTTTGATTCTGATGGGGCTGGCACGCTTTGGTCGCCTGATTGAGTATATTCCGGTTT
CCGTCACCTTAGGTTTCACCTCGGGTATCGGGATCACCATCGGTACCATGCAGATTAAAGATTTTCTCGGTCTGCAAATG
GCCCATGTCCCGGAACATTATCTACAAAAAGTCGGCGCATTATTTATGGCGCTGCCGACCATTAATGTGGGTGATGCAGC
CATTGGCATTGTGACGCTTGGCATTCTGGTTTTCTGGCCGCGTCTGGGCATACGTTTACCCGGCCACCTTCCGGCCTTGC
TGGCTGGTTGCGCGGTGATGGGGATTGTTAACCTGCTCGGCGGACATGTTGCTACCATCGGTTCGCAGTTCCATTACGTT
CTGGCCGATGGTTCTCAGGGTAACGGTATTCCGCAATTGCTGCCACAACTGGTGCTGCCGTGGGATCTACCTGATTCAGA
ATTCACGCTAACCTGGGATTCTATTCGCACACTGCTGCCTGCGGCATTCTCAATGGCAATGCTCGGCGCAATCGAATCTC
TGCTCTGCGCCGTGGTGCTGGATGGTATGACCGGGACGAAACACAAGGCGAACAGCGAACTGGTTGGACAGGGACTGGGG
AATATTATCGCTCCGTTCTTTGGTGGCATTACCGCTACAGCTGCCATCGCGCGTTCTGCCGCTAACGTCCGTGCCGGGGC
AACTTCCCCTATCTCGGCGGTGATCCACTCTATTCTGGTTATTCTTGCCCTGCTGGTACTGGCACCGCTGCTCTCCTGGC
TGCCGCTTTCCGCCATGGCAGCCCTGCTGTTGATGGTGGCGTGGAACATGAGTGAAGCGCACAAAGTGGTCGACTTGCTG
CGTCATGCACCGAAAGATGACATCATTGTCATGCTGTTGTGCATGTCGCTGACCGTGCTGTTTGATATGGTTATTGCCAT
CAGCGTGGGGATCGTGCTGGCATCGCTGCTGTTTATGCGTCGTATCGCACGTATGACTCGCCTGGCACCGGTAGTCGTAG
ATGTTCCAGACGATGTCCTGGTACTGCGCGTTATTGGCCCGCTGTTTTTTGCTGCTGCTGAAGGCTTGTTCACGGACCTG
GAGTCACGTCTTGAAGGCAAACGGATTGTGATTCTGAAGTGGGATGCCGTTCCGGTACTTGATGCAGGTGGTCTTGATGC
GTTCCAGCGTTTTGTGAAGCGTCTGCCCGAAGGATGTGAACTGCGCGTGTGCAACGTGGAATTCCAGCCACTGCGCACGA
TGGCTCGCGCAGGCATTCAACCGATCCCGGGACGCCTTGCTTTCTTCCCGAATCGTCGCGCGGCGATGGCGGATTTATAA

Upstream 100 bases:

>100_bases
GCGGCGGGTTTTTTTGTCTGTAATATCCATTTGTATGACCTATGCCTCCTTCACCTGCCATTTAGTTGACAGATGATGCG
CTCACGGATGAAACATTATT

Downstream 100 bases:

>100_bases
GTACGAAATTGACCAGTCAGCGCAAACTGACTGGTCAGTAAACTGCAGTATTTGTTAGCTATGACGGCGATTATCGCTAC
GGCGGCAACGTTTGTCATAG

Product: putative sulfate transporter YchM

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRF
SVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGVFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
LADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLG
NIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLL
RHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL

Sequences:

>Translated_559_residues
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRF
SVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGVFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
LADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLG
NIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLL
RHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL
>Mature_559_residues
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRF
SVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGVFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
LADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLG
NIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLL
RHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL

Specific function: Possible sulfate transporter [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=503, Percent_Identity=27.037773359841, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI262206075, Length=503, Percent_Identity=27.037773359841, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI262206069, Length=503, Percent_Identity=27.037773359841, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI262206063, Length=503, Percent_Identity=27.037773359841, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4557535, Length=489, Percent_Identity=23.1083844580777, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI94721253, Length=482, Percent_Identity=23.0290456431535, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94721255, Length=482, Percent_Identity=23.0290456431535, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94721257, Length=482, Percent_Identity=23.0290456431535, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI94721259, Length=482, Percent_Identity=23.0290456431535, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI45827800, Length=389, Percent_Identity=22.879177377892, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI39752683, Length=389, Percent_Identity=22.879177377892, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI45827802, Length=402, Percent_Identity=21.8905472636816, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4505697, Length=433, Percent_Identity=22.8637413394919, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI269784651, Length=379, Percent_Identity=23.2189973614776, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI20336282, Length=527, Percent_Identity=21.2523719165085, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI16306483, Length=510, Percent_Identity=21.7647058823529, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI47131207, Length=545, Percent_Identity=23.8532110091743, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI20336272, Length=545, Percent_Identity=23.8532110091743, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI100913030, Length=478, Percent_Identity=23.2217573221757, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87081859, Length=559, Percent_Identity=99.6422182468694, Blast_Score=1103, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17566848, Length=557, Percent_Identity=24.9551166965889, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI86564196, Length=445, Percent_Identity=23.8202247191011, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193203292, Length=384, Percent_Identity=23.1770833333333, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323121, Length=457, Percent_Identity=23.1947483588621, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325260, Length=520, Percent_Identity=22.8846153846154, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319771, Length=193, Percent_Identity=29.5336787564767, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19922482, Length=423, Percent_Identity=25.7683215130024, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI85815873, Length=479, Percent_Identity=26.0960334029228, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24663084, Length=443, Percent_Identity=27.9909706546275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357695, Length=443, Percent_Identity=27.9909706546275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21358229, Length=463, Percent_Identity=26.7818574514039, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24649801, Length=453, Percent_Identity=26.2693156732892, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24651449, Length=448, Percent_Identity=23.8839285714286, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21358633, Length=434, Percent_Identity=25.5760368663594, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355087, Length=171, Percent_Identity=30.9941520467836, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647160, Length=178, Percent_Identity=30.3370786516854, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666186, Length=441, Percent_Identity=24.9433106575964, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018045
- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59417; Mature: 59417

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50801 STAS ; PS01130 SLC26A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGVFLILMG
HHHHHHHHHHEEEEECCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQMAHVPEHYLQKVGALFMALPT
HHHHHHHHHHHCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
INVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEE
LADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVL
EECCCCCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGMTGTKHKANSELVGQGLGNIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLLRHAPKDDIIVMLLCMSLTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQ
HHHCCCCEEEEEEECCCCEECCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCC
PIPGRLAFFPNRRAAMADL
CCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGVFLILMG
HHHHHHHHHHEEEEECCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQMAHVPEHYLQKVGALFMALPT
HHHHHHHHHHHCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
INVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEE
LADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVL
EECCCCCCCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGMTGTKHKANSELVGQGLGNIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLLRHAPKDDIIVMLLCMSLTVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQ
HHHCCCCEEEEEEECCCCEECCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCC
PIPGRLAFFPNRRAAMADL
CCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]