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The map label for this gene is ydfQ

Identifier: 218699876

GI number: 218699876

Start: 1573079

End: 1573612

Strand: Direct

Name: ydfQ

Synonym: ECIAI39_1503

Alternate gene names: 218699876

Gene position: 1573079-1573612 (Clockwise)

Preceding gene: 218699875

Following gene: 218699877

Centisome position: 30.65

GC content: 50.56

Gene sequence:

>534_bases
ATGAACACAAAAATCAGATACGGCCTGTCGGCTGCCGTTCTGGCGCTGATTGGTGCTGGCGCATCTGCTCCTCAGATACT
TGACCAGTTTCTGGACGAAAAAGAAGGTAACCACACAATGGCATACCGCGATGGTTCTGGCATATGGACCATCTGTCGGG
GTGCCACAGTGGTGGATGGAAAAACCGTTTTTCCCAATATGAAACTGTCGAAGGAAAAATGCGACCAGGTCAACGCCATT
GAGCGTGATAAGGCGCTGGCATGGGTGGAGCGCAATATTAAAGTACCACTGACCGAACCACAAAAAGCGGGTATCGCGTC
ATTTTGTCCCTATAACATTGGCCCCGGTAAGTGTTTCCCGTCGACGTTTTATAAGCGGCTGAATGCTGGTGATCGTAAAG
GTGCATGCGAAGCGATTCGCTGGTGGATTAAGGATGGCGGACGCGATTGCCGCATTCGTTCAAATAACTGTTACGGTCAG
GTTATTCGTCGTGACCAGGAGAGCGCATTAACCTGCTGGGGGATAGAACAGTGA

Upstream 100 bases:

>100_bases
AAAAATTGTCAGAAAAAGTTGAGTCTTATCTGCAGCATCAGTACTCCTTTAAGATTGAAAATCCTGCCAATAAGCACGAG
CGTCCTCATCATAAATATCT

Downstream 100 bases:

>100_bases
ATCAGATATTCATGGTGATTTTTCTCGTGTTGTCAGGATTTATCGTCGGAAATGTCTGGAGCGACCGAGGATGGCAAAAA
AAATGGGCGGAACGTGATGC

Product: putative membrane-associated lysozyme; Qin prophage

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAI
ERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VIRRDQESALTCWGIEQ

Sequences:

>Translated_177_residues
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAI
ERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VIRRDQESALTCWGIEQ
>Mature_177_residues
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAI
ERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VIRRDQESALTCWGIEQ

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family

Homologues:

Organism=Escherichia coli, GI1787836, Length=177, Percent_Identity=100, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1786768, Length=147, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYSQ_ECOLI (P76159)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64910
- RefSeq:   AP_002176.1
- RefSeq:   NP_416072.1
- ProteinModelPortal:   P76159
- SMR:   P76159
- STRING:   P76159
- EnsemblBacteria:   EBESCT00000000604
- EnsemblBacteria:   EBESCT00000014721
- GeneID:   946100
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1546
- KEGG:   eco:b1554
- EchoBASE:   EB3590
- EcoGene:   EG13829
- eggNOG:   COG3772
- GeneTree:   EBGT00050000008676
- HOGENOM:   HBG756417
- OMA:   DQFLNEK
- ProtClustDB:   CLSK879915
- BioCyc:   EcoCyc:G6827-MONOMER
- Genevestigator:   P76159
- GO:   GO:0019835
- InterPro:   IPR002196

Pfam domain/function: PF00959 Phage_lysozyme

EC number: =3.2.1.17

Molecular weight: Translated: 19663; Mature: 19663

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: ACT_SITE 35-35 ACT_SITE 44-44

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCEEECC
KTVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFP
CEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
STFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQVIRRDQESALTCWGIEQ
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCEEEECCCC
>Mature Secondary Structure
MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRDGSGIWTICRGATVVDG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCEEECC
KTVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFP
CEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
STFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQVIRRDQESALTCWGIEQ
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503