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The map label for this gene is dmsD

Identifier: 218699843

GI number: 218699843

Start: 1543384

End: 1543998

Strand: Reverse

Name: dmsD

Synonym: ECIAI39_1467

Alternate gene names: 218699843

Gene position: 1543998-1543384 (Counterclockwise)

Preceding gene: 218699844

Following gene: 218699842

Centisome position: 30.09

GC content: 53.98

Gene sequence:

>615_bases
ATGACCCATTTTTCACAGCAAGATAATTTTTCTGTCGCGGCGCGCGTGTTGGGCGCGCTGTTTTATTACGCTCCAGAGAG
TGCGGAAGCCGCCCCCCTAGTTGCGGCACTCACCCGTGACGGCTGGGAAACTCAGTGGCCTCTACCAGAAGCGTCATTAG
CGCCGCTGGTGACTGCTTTTCAGACACAGAGTGAAGAGACTCACGCCCAGGCCTGGCAGCGTTTGTTTGTCGGCCCGTGG
GCACTGCCGTCACCGCCGTGGGGATCGGTCTGGCTGGATCGCGAATCTGTGCTGTTTGGCGATTCAACATTGGCACTTCG
TCAGTGGATGCGCGAGAAAGGCATTCAGTTTGAAATGCAGCAAAACGAACCGGAAGATCATTTTGGTTCACTGCTGTTGA
TGGCTGCGTGGTTGGCGGAGAATGGTCGCCAGACAGAATGCGAAGAATTGCTGGCATGGCACCTTTTTCCGTGGTCAACA
CGTTTTCTTGACGTTTTTATCGAAAAAGCAGAACACCCTTTCTACCGTGCACTGGGTGAACTCGCTCGCTTAACGCTGGC
GCAATGGCAATCACAACTGTTGATTCCTGTCGCGGTTAAACCGCTGTTTCGATAG

Upstream 100 bases:

>100_bases
CGGGCGTGTGCTCTTTTATGGCCTGCACATGACGGTAGGAATGGCTATTGCAGGTTAACAAATTGGTGCGGGGCAACCCG
CACATTTCAGGATGTTAGGA

Downstream 100 bases:

>100_bases
GATCACCGTAATATTGCCGGATGGTGACGATTACGCGCGATTCGGCAATAATACGTTACAGTGTCACGTTTTTTATCTCT
TAAAGCACGCACTGCTTTTG

Product: twin-argninine leader-binding protein DmsD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAALTRDGWETQWPLPEASLAPLVTAFQTQSEETHAQAWQRLFVGPW
ALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMQQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR

Sequences:

>Translated_204_residues
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAALTRDGWETQWPLPEASLAPLVTAFQTQSEETHAQAWQRLFVGPW
ALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMQQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR
>Mature_203_residues
THFSQQDNFSVAARVLGALFYYAPESAEAAPLVAALTRDGWETQWPLPEASLAPLVTAFQTQSEETHAQAWQRLFVGPWA
LPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMQQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTR
FLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR

Specific function: Binds to the twin-arginine signal peptide of dmsA and torA. Could be required for the biogenesis of DMSO reductase rather than for the targeting of dmsA to the inner membrane [H]

COG id: COG3381

COG function: function code R; Uncharacterized component of anaerobic dehydrogenases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Cytoplasm (By similarity). Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the torD/dmsD family. DmsD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081942, Length=204, Percent_Identity=98.0392156862745, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787272, Length=180, Percent_Identity=30, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020945 [H]

Pfam domain/function: PF02613 Nitrate_red_del [H]

EC number: NA

Molecular weight: Translated: 23370; Mature: 23239

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAALTRDGWETQWPLPEASLAPLVTAF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QTQSEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMQ
HCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCEEEEC
QNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTRFLDVFIEKAEHPFYRALGE
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LARLTLAQWQSQLLIPVAVKPLFR
HHHHHHHHHHHCEEHHHHHCCCCC
>Mature Secondary Structure 
THFSQQDNFSVAARVLGALFYYAPESAEAAPLVAALTRDGWETQWPLPEASLAPLVTAF
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QTQSEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMQ
HCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCEEEEC
QNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTRFLDVFIEKAEHPFYRALGE
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
LARLTLAQWQSQLLIPVAVKPLFR
HHHHHHHHHHHCEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]