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The map label for this gene is slyA

Identifier: 218699789

GI number: 218699789

Start: 1486420

End: 1486854

Strand: Direct

Name: slyA

Synonym: ECIAI39_1413

Alternate gene names: 218699789

Gene position: 1486420-1486854 (Clockwise)

Preceding gene: 218699785

Following gene: 218699791

Centisome position: 28.96

GC content: 47.82

Gene sequence:

>435_bases
TTGGAATCGCCACTAGGTTCTGATCTGGCACGGTTGGTGCGCATATGGCGTGCTCTGATAGACCATCGCCTGAAACCGCT
GGAGTTAACACAAACCCATTGGGTTACGTTACACAATATCCATCAGTTACCTCCAGACCAGTCGCAAATTCAACTGGCAA
AAGCGATTGGCATCGAGCAGCCATCACTGGTCCGTACTCTGGACCAACTGGAAGAAAAAGGGTTAATTTCGCGTCAAACT
TGTGCCAGCGATCGTCGGGCTAAACGTATTAAACTGACGGAAAAGGCAGAGCCGCTGATCAGCGAAATGGAAGCTGTTAT
TAACAAAACCCGCGCGGAAATTTTACATGGCATCTCCGCAGAGGAACTGGAACAACTGATTAAGCTCATCGCAAAACTTG
AGCATAATATCATTGAGTTACAGGCCAAAGGGTGA

Upstream 100 bases:

>100_bases
TAACCAAATGCAGCAATACATTTGTTTTAGCAATACAATTGCTGCACACTATTCTAAAAGCCGCATAATATCTTAGCAAG
CTAATTATAAGGAGATGAAA

Downstream 100 bases:

>100_bases
AATGAAGGGGGCGTGTGGTCAGTAACCTGACCACACGCAAACTTATTTAGCGCGGGGAAACGGTCACCTGACTGCCATTG
CTGGCCAGTACGACACGTTG

Product: transcriptional regulator SlyA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQT
CASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG

Sequences:

>Translated_144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQT
CASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG
>Mature_144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQT
CASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG

Specific function: Transcription regulator that can both activate or repress expression [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=144, Percent_Identity=99.3055555555556, Blast_Score=282, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16380; Mature: 16380

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EELEQLIKLIAKLEHNIIELQAKG
HHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EELEQLIKLIAKLEHNIIELQAKG
HHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA