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The map label for this gene is int

Identifier: 218699465

GI number: 218699465

Start: 1161592

End: 1162854

Strand: Reverse

Name: int

Synonym: ECIAI39_1081

Alternate gene names: 218699465

Gene position: 1162854-1161592 (Counterclockwise)

Preceding gene: 218699466

Following gene: 218699460

Centisome position: 22.66

GC content: 52.49

Gene sequence:

>1263_bases
ATGTCCCTTACCAGCGCAAAAATCCGCACCCTCAAGCCTTCTGATAAACCCTTTAAAGTCTCCGATTCTCACGGTCTGTA
TCTGCGGGTCAAGCCGGGTAGCTCCCGCCACTGGTATCTCAAATACCGTATTAGCGGTAAAGAATCCCGCATTGCGCTGG
GTACCTATCCAGCCATCTCCCTGTCTGATGCGCGACAGCAACGTGAAGGTATCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGTACGTGGCTCACGAACACCGGAGAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACAGGAAATGGTCGCAGAACACCGCCGACCGTCTGCTTGCCAGTCTGAACAATCACATCTTTCCGGTCATCGGGA
ACCTACCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAGGGATCGAGGAAAAAGGTCTGCTGGAGGTT
GCGTCCCGCACACGGCAGCACCTGAGTAACATAATGCGCCATGCGGTCCATCAGGAGTTAATCGATACGAACCCTGCAGC
AAACCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCGCTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGCCGTGAACTGACCCGGCATGCCGTTCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCAACGCGAGAACCCAT
TATTGGCGTGCGTTATTCCGGCCGCGGGGCAAAAATGCGAATGCCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGTTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCGCAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTGGAAGCCCGTAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Upstream 100 bases:

>100_bases
GAAAACTCTTCTCAGTGCATTTTGATTTTACCCTACGCATCGGGAAAAATTGGTGGTCAAATCTGGGGTCAGGTTAGTTC
GATAATGGAGTGACCCCCAT

Downstream 100 bases:

>100_bases
TATACTAACGAATCCCACACTCTGGCAAATTACCACCACCTCCACAGGAGGTGGTTCTATATAGACTTTTATCAACTTCA
TGACGAAAAACACCTATTTT

Product: integrase

Products: NA

Alternate protein names: Int(P4) [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGSSRHWYLKYRISGKESRIALGTYPAISLSDARQQREGIRKMLALNIN
PVQQRAAVRGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

Sequences:

>Translated_420_residues
MSLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGSSRHWYLKYRISGKESRIALGTYPAISLSDARQQREGIRKMLALNIN
PVQQRAAVRGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP
>Mature_419_residues
SLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGSSRHWYLKYRISGKESRIALGTYPAISLSDARQQREGIRKMLALNINP
VQQRAAVRGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVA
SRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRSS
ELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCE
NTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLE
ACRESYAPPYTIGKNKFIP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=406, Percent_Identity=33.0049261083744, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788690, Length=401, Percent_Identity=30.1745635910224, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI145693166, Length=414, Percent_Identity=31.4009661835749, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48051; Mature: 47920

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGSSRHWYLKYRISGKESRIALGTYPAIS
CCCCCCHHEEECCCCCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGIRKMLALNINPVQQRAAVRGSRTPEKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVASRTRQHLSNIMRHAVHQEL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
HCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
SLTSAKIRTLKPSDKPFKVSDSHGLYLRVKPGSSRHWYLKYRISGKESRIALGTYPAIS
CCCCCHHEEECCCCCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCCC
LSDARQQREGIRKMLALNINPVQQRAAVRGSRTPEKVFKNVALAWHKSNRKWSQNTADRL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEVASRTRQHLSNIMRHAVHQEL
HHHHCCCEEEEECCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
HCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHC
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKD
CCCCEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHH
ITGNNELIFPGDHNPYKPMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAK
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCHH
DAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYLEACRESYAPPYTIGKNKFIP
HHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]