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The map label for this gene is rtcB [C]

Identifier: 218699084

GI number: 218699084

Start: 726956

End: 728353

Strand: Reverse

Name: rtcB [C]

Synonym: ECIAI39_0687

Alternate gene names: 218699084

Gene position: 728353-726956 (Counterclockwise)

Preceding gene: 218699090

Following gene: 218699075

Centisome position: 14.19

GC content: 53.15

Gene sequence:

>1398_bases
ATGCATCATCTTTCAAGGCTTGATAAAGCCTTTCTGCGCAAAGGGATCCAACTTTCCCGCGCCAACAATATTGTTTCATT
ATGTCGTCCATCAGGAGCCAGTGCCCACGTACTGCTGCCGGACGAACTGCCGCTGGAAGAAAAAGTAGTGACACAACTGC
TTGATTTTGCAGAAGTGAAGATACCAGACCATCCAGGTTACGTACGCCAGACCTGTGCGACGCCAGATTTTCATCCCGGC
AATGGCGTCCCCGTTGGCGCGGTAGTCGCCTCTACGCCGGATTTAGTCATTCCTGCGGCCATCGGCACCGATATTTCTTG
TGGCATGCGGCTGCTGACGACCGGATTAACCCTTGAGCAAGCCGAAGCGAATAAAGAAATAATCACTCAGCGGTTAACAC
AAGTGTTACTGCAAAATGAGCGCGATGTTCCGTTATCCGCACGAGCGTTCACCGCGCTTTTTGATGGCGGACCGGCAGAT
TGCATGTCGGCCTTGCCATCAGCAGGTCTCTGGACACGTACAAATATCCCCCGAATGACGCAAGAGATTGACCGCTGCAT
TGGGCTTAACGAGCATAACAGTCATTCGCGTTATGCCCCACCCGCCCTACTGGTAACGGACCGCCCATTACTCCGCGATC
CTTGTCTTGGTACGCCGGGTTCAGGTAATCATTTTATTGAACTTCAGGTGGTTGATAGCGTGGTTGATCGCCATGTTGCC
TGGCAACAAGGGCTGAAAACGGGCGATATTGTGGTGATGATCCACAGTGGATCGCGAGATGTTGGCTTTTACGTCGGAAG
ACGCTGGATGGATCGCGCCCGTGCTGAATGGCCCACCGGACATAAACATCCACAAAGCGGGTTATATGGCCTGGCAGGCG
GACTGGCGGAGGAATATCTACAAGCGATGGGAATGGCGGCGCGTTACGCGTGGTTAAATCGCGTCACAATTGCCGAAATG
GTGCGCGTATGTCTTGCTAATCTCTTTCATCAGGACAATTCGCATCTGGTGGTGGATGTGCCGCATAACATCATCCTTCG
CGAGTATGAAATGAATATTCATCGCAAAGGTGCAACACCGGCACGCGCGGGCAATCTGGCGTTAATCCCCGGTTCAATGG
GCGATTATTCGTGGCTTGCAGTCGGTTGCGGCAACCCGGAGTGGCTGTGGTCTTGCAGTCACGGAGCAGGACGCAGCCAG
CGTCGGCAGGCCATGCACTCACGCGCGACTGAAGAGTCAACGTTGCCGTGGCAATGCGTCACATTGCGCGAAGAACGGCG
TATTGAAGAAGCGCCAGCTGCTTATAAAGATATTGGTCCGGTTATCGAAGCCCAACAAGAGGCCGGATTAATTCATCCAG
CGGTTAGATTCCGACCGTGGTTAACGTTTAAGGCATAA

Upstream 100 bases:

>100_bases
ACGCGCGTTTTCTTTCCCTTTTGCTGGCTGCTGACCGGAAAGACAAAATTACCCTCGCAATAAAGGGGGTTGTTTAACGT
CTATATTTCAGGACAGCGTT

Downstream 100 bases:

>100_bases
AAAAAGGCCATCATATGATGACCAACCATGTCGAAACCGACAGCCCTTCGCCATTCCTGTAGAGGGAAGCGGCGAGGGCT
ATTTCTTATTACAGATATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MHHLSRLDKAFLRKGIQLSRANNIVSLCRPSGASAHVLLPDELPLEEKVVTQLLDFAEVKIPDHPGYVRQTCATPDFHPG
NGVPVGAVVASTPDLVIPAAIGTDISCGMRLLTTGLTLEQAEANKEIITQRLTQVLLQNERDVPLSARAFTALFDGGPAD
CMSALPSAGLWTRTNIPRMTQEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGTPGSGNHFIELQVVDSVVDRHVA
WQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAEWPTGHKHPQSGLYGLAGGLAEEYLQAMGMAARYAWLNRVTIAEM
VRVCLANLFHQDNSHLVVDVPHNIILREYEMNIHRKGATPARAGNLALIPGSMGDYSWLAVGCGNPEWLWSCSHGAGRSQ
RRQAMHSRATEESTLPWQCVTLREERRIEEAPAAYKDIGPVIEAQQEAGLIHPAVRFRPWLTFKA

Sequences:

>Translated_465_residues
MHHLSRLDKAFLRKGIQLSRANNIVSLCRPSGASAHVLLPDELPLEEKVVTQLLDFAEVKIPDHPGYVRQTCATPDFHPG
NGVPVGAVVASTPDLVIPAAIGTDISCGMRLLTTGLTLEQAEANKEIITQRLTQVLLQNERDVPLSARAFTALFDGGPAD
CMSALPSAGLWTRTNIPRMTQEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGTPGSGNHFIELQVVDSVVDRHVA
WQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAEWPTGHKHPQSGLYGLAGGLAEEYLQAMGMAARYAWLNRVTIAEM
VRVCLANLFHQDNSHLVVDVPHNIILREYEMNIHRKGATPARAGNLALIPGSMGDYSWLAVGCGNPEWLWSCSHGAGRSQ
RRQAMHSRATEESTLPWQCVTLREERRIEEAPAAYKDIGPVIEAQQEAGLIHPAVRFRPWLTFKA
>Mature_465_residues
MHHLSRLDKAFLRKGIQLSRANNIVSLCRPSGASAHVLLPDELPLEEKVVTQLLDFAEVKIPDHPGYVRQTCATPDFHPG
NGVPVGAVVASTPDLVIPAAIGTDISCGMRLLTTGLTLEQAEANKEIITQRLTQVLLQNERDVPLSARAFTALFDGGPAD
CMSALPSAGLWTRTNIPRMTQEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGTPGSGNHFIELQVVDSVVDRHVA
WQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAEWPTGHKHPQSGLYGLAGGLAEEYLQAMGMAARYAWLNRVTIAEM
VRVCLANLFHQDNSHLVVDVPHNIILREYEMNIHRKGATPARAGNLALIPGSMGDYSWLAVGCGNPEWLWSCSHGAGRSQ
RRQAMHSRATEESTLPWQCVTLREERRIEEAPAAYKDIGPVIEAQQEAGLIHPAVRFRPWLTFKA

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=451, Percent_Identity=27.9379157427938, Blast_Score=148, Evalue=9e-36,
Organism=Escherichia coli, GI2367224, Length=428, Percent_Identity=30.8411214953271, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17506665, Length=453, Percent_Identity=29.5805739514349, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24585217, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 51289; Mature: 51289

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHLSRLDKAFLRKGIQLSRANNIVSLCRPSGASAHVLLPDELPLEEKVVTQLLDFAEVK
CCHHHHHHHHHHHCCCCHHHCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEE
IPDHPGYVRQTCATPDFHPGNGVPVGAVVASTPDLVIPAAIGTDISCGMRLLTTGLTLEQ
CCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEHHCCCCHHHHHHHHHCCCCHHH
AEANKEIITQRLTQVLLQNERDVPLSARAFTALFDGGPADCMSALPSAGLWTRTNIPRMT
HHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCEECCCCCHHH
QEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGTPGSGNHFIELQVVDSVVDRHVA
HHHHHHCCCCCCCCCCCCCCCEEEEECCCHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
WQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAEWPTGHKHPQSGLYGLAGGLAEEYL
HHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
QAMGMAARYAWLNRVTIAEMVRVCLANLFHQDNSHLVVDVPHNIILREYEMNIHRKGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCEEECCCCC
ARAGNLALIPGSMGDYSWLAVGCGNPEWLWSCSHGAGRSQRRQAMHSRATEESTLPWQCV
CCCCCEEEECCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEE
TLREERRIEEAPAAYKDIGPVIEAQQEAGLIHPAVRFRPWLTFKA
EEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEECC
>Mature Secondary Structure
MHHLSRLDKAFLRKGIQLSRANNIVSLCRPSGASAHVLLPDELPLEEKVVTQLLDFAEVK
CCHHHHHHHHHHHCCCCHHHCCCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEE
IPDHPGYVRQTCATPDFHPGNGVPVGAVVASTPDLVIPAAIGTDISCGMRLLTTGLTLEQ
CCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEHHCCCCHHHHHHHHHCCCCHHH
AEANKEIITQRLTQVLLQNERDVPLSARAFTALFDGGPADCMSALPSAGLWTRTNIPRMT
HHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCEECCCCCHHH
QEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGTPGSGNHFIELQVVDSVVDRHVA
HHHHHHCCCCCCCCCCCCCCCEEEEECCCHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
WQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAEWPTGHKHPQSGLYGLAGGLAEEYL
HHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
QAMGMAARYAWLNRVTIAEMVRVCLANLFHQDNSHLVVDVPHNIILREYEMNIHRKGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCEEECCCCC
ARAGNLALIPGSMGDYSWLAVGCGNPEWLWSCSHGAGRSQRRQAMHSRATEESTLPWQCV
CCCCCEEEECCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEE
TLREERRIEEAPAAYKDIGPVIEAQQEAGLIHPAVRFRPWLTFKA
EEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]