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The map label for this gene is ycbG [H]

Identifier: 218699065

GI number: 218699065

Start: 707422

End: 708135

Strand: Reverse

Name: ycbG [H]

Synonym: ECIAI39_0668

Alternate gene names: 218699065

Gene position: 708135-707422 (Counterclockwise)

Preceding gene: 218699074

Following gene: 218699064

Centisome position: 13.8

GC content: 48.04

Gene sequence:

>714_bases
ATGAGTGAGAGTGCGTTATTGACCAGCGTAACGTTATCGTCACAGGTCAAAAATCATATTCTTAATCTGATCGCCGAACA
AAAATTGACACCGGGGATGCCAGTTCCCAGTGAAATTCAGTTGATTCAGAAATTGGGCGTCAGTCGGGGTATTGTGCGTG
AGGCCTATCGTTCACTTGCCGCCCTGGGGATTCTGGAAACGCACAGCGGTAAAGTGCCACGGATCAAAAAATTTGATGAT
GAAGTGCTGCGCGTGGTGTTTGGATTTGCCCTGGCGACCGAACAAGTAACAACAGAGCAAATTCTTCAAGTACGTCGCTG
GCTAGAGTTGGGCGTTGTGGAAGCTGCTGCCCGTAATGGCGGAGAAGAAGATTTTGCTAACCTACGGGCTGAAATGGCAA
AAATCCGCGAACAGTTCGATGATGTCGAAAGCTTTATCACCCATGACATCCGCTTCCATCAGTTACTCGCCGTTGCCTCA
AAAAATCCGCTTTTTATGATGTTATTGCAGGCATTACATCAGCAATTGCGGCAATCCATCCAGGAGGGATTAAACGCCCA
AAGCGATCAGAAAGAGTATGGCAATCACATCATCACACTACACCAGAAAATCTGCGACGCTGTGTGTGCCAGAGATGTCG
AAACGGCGACTCTAGCCATGAAATCACACTTCGACAGCCCGGTCAGCGCACTGATCAATAATTCCTCGCCATAA

Upstream 100 bases:

>100_bases
GTAGTCTATTGATAATCAAGGGTTCTGGAGGAAAATATGAAGGATACAGTCCCGGTATTCTGGATTTTACCGACCAGGAA
AAAGTACAACAGGAGTAAAA

Downstream 100 bases:

>100_bases
TACTTATTTCAGTTCAATCATTTGCTCTTCCCTCTTTTACAAATGAGAGGGAGACAACGGTACTTAATACGCCCTTTAGC
CAAAATCTGTCTTTTTCTTG

Product: putative GntR family regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQKLGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDD
EVLRVVFGFALATEQVTTEQILQVRRWLELGVVEAAARNGGEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVAS
KNPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATLAMKSHFDSPVSALINNSSP

Sequences:

>Translated_237_residues
MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQKLGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDD
EVLRVVFGFALATEQVTTEQILQVRRWLELGVVEAAARNGGEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVAS
KNPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATLAMKSHFDSPVSALINNSSP
>Mature_236_residues
SESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQKLGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDDE
VLRVVFGFALATEQVTTEQILQVRRWLELGVVEAAARNGGEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVASK
NPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATLAMKSHFDSPVSALINNSSP

Specific function: Sialic acid (NANA) and N-acetylmannosamine utilization [C]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=230, Percent_Identity=28.695652173913, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789353, Length=214, Percent_Identity=28.9719626168224, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790032, Length=222, Percent_Identity=26.5765765765766, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI48994955, Length=208, Percent_Identity=26.4423076923077, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26381; Mature: 26249

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQKLGVSRGIVREAYRSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
ALGILETHSGKVPRIKKFDDEVLRVVFGFALATEQVTTEQILQVRRWLELGVVEAAARNG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVASKNPLFMMLLQALHQQLRQSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATLAMKSHFDSPVSALINNSSP
HHHCCCCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure 
SESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQKLGVSRGIVREAYRSLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
ALGILETHSGKVPRIKKFDDEVLRVVFGFALATEQVTTEQILQVRRWLELGVVEAAARNG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVASKNPLFMMLLQALHQQLRQSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATLAMKSHFDSPVSALINNSSP
HHHCCCCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]