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The map label for this gene is ybdG

Identifier: 218698949

GI number: 218698949

Start: 583103

End: 584350

Strand: Reverse

Name: ybdG

Synonym: ECIAI39_0552

Alternate gene names: 218698949

Gene position: 584350-583103 (Counterclockwise)

Preceding gene: 218698950

Following gene: 218698943

Centisome position: 11.39

GC content: 47.6

Gene sequence:

>1248_bases
ATGCAGGATTTAATATCCCAGGTTGAAGATTTAGCGGGTATTGAGATCGATCACACCACCTCAATGGTGATGATTTTCGG
TATTATTTTTCTGACCGCCGTCGTGGTGCATATTTTTTTGCATTGGGTGGTACTGCGGACCTTCGAAAAACGTGCCATCG
CCAGTTCACGGCTATGGTTGCAAATCATTACCCAGAATAAACTCTTCCACCGTTTAGCTTTTACCCTGCAGGGGATTATC
GTCAATATTCAGGCGGTATTCTGGCTGCAAAAAGGCACCGAAGCGGCAGATATTCTGACTACCTGCGCGCAGTTGTGGAT
CATGATGTATGCGCTGCTTTCAGTCTTCTCGTTGCTGGATGTTATTTTGAATCTGGCGCAGAAATTCCCGGCGGCATCTC
AGTTACCGCTGAAAGGGATATTTCAGGGGATTAAACTGATCGGCGCGATTCTGGTCGGCATTTTGATGATCTCGCTGCTG
ATTGGTCAGTCGCCAGCGATTCTGATCAGCGGTCTTGGTGCAATGGCTGCCGTGCTAATGTTGGTATTTAAAGATCCGAT
TCTTGGTCTGGTGGCAGGTATTCAGCTTTCCGCGAACGATATGTTGAAACTGGGCGACTGGCTGGAGATGCCGAAATACG
GCGCGGATGGCGCGGTGATCGATATTGGGTTAACCACCGTCAAAGTGCGTAACTGGGACAATACCATTACCACTATTCCC
ACCTGGTCTCTGGTCTCTGACTCCTTTAAAAACTGGAGCGGGATGTCAGCATCTGGCGGGCGACGTATTAAGCGCAGTAT
CAGTATTGATGTCACCAGTATTCGTTTTCTTGATGAAGACGAAATGCAACGGCTGAATAAAGCGCACTTGTTAAAGCCTT
ATTTAACCAGCCGCCACAAGGAAATTAATGAGTGGAATCGCCAGCAAGGTTCTACGGAGTCGGTATTAAACCTGCGCCGA
ATGACCAATATTGGAACCTTTCGTGCCTATCTGAACGAATATCTACGTAACCATCCGCGAATTCGTAAAGATATGACCTT
AATGGTACGCCAACTGGCTCCTGGCGATAACGGTTTACCGCTCGAGATCTATGCGTTTACCAACACCGTGGTGTGGCTGG
AATATGAAAGCATTCAGGCTGATATATTCGACCACATATTTGCGATTGTCGAAGAGTTTGGTCTGCGACTTCATCAGTCG
CCAACTGGCAATGATATTCGCTCTCTGGCGGGTGCATTTAAGCAGTAA

Upstream 100 bases:

>100_bases
TTGCCGGGCATCTGCCCGGCTATTTCCCCTCAGATTCTCCTGATTTGCATAACCCTGTTTCAGCCGTCATCATAGTCTGC
TGTTGTATAAAGGAGACGTT

Downstream 100 bases:

>100_bases
TTAAAAAAACCGCTCTTATCGAATGGATGAGAGCGGTTTCGGATGGTTGACATCATTTTGTCGGATACGGCGTGAATGCC
TTATTTCCGACGCAGCGTTT

Product: putative membrane protein; putative channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGII
VNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHKEINEWNRQQGSTESVLNLRR
MTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQS
PTGNDIRSLAGAFKQ

Sequences:

>Translated_415_residues
MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGII
VNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHKEINEWNRQQGSTESVLNLRR
MTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQS
PTGNDIRSLAGAFKQ
>Mature_415_residues
MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGII
VNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHKEINEWNRQQGSTESVLNLRR
MTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQS
PTGNDIRSLAGAFKQ

Specific function: Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786791, Length=415, Percent_Identity=99.5180722891566, Blast_Score=839, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 46637; Mature: 46637

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVVLRTFEKRAIASSRLWL
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLLIGQSPAILISGLGAMAAVLM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
HHHHCHHHHHHHCCEECCCHHHHHHHHHHCCCCCCCCCEEEECEEEEEEECCCCCEEECC
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHK
CHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
EINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
LEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQSPTGNDIRSLAGAFKQ
EEEEEEECEEEEEEEHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVVLRTFEKRAIASSRLWL
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLLIGQSPAILISGLGAMAAVLM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
HHHHCHHHHHHHCCEECCCHHHHHHHHHHCCCCCCCCCEEEECEEEEEEECCCCCEEECC
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHK
CHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
EINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
LEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQSPTGNDIRSLAGAFKQ
EEEEEEECEEEEEEEHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 7813889 [H]