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The map label for this gene is 218698685

Identifier: 218698685

GI number: 218698685

Start: 301591

End: 301833

Strand: Reverse

Name: 218698685

Synonym: ECIAI39_0271

Alternate gene names: NA

Gene position: 301833-301591 (Counterclockwise)

Preceding gene: 218698686

Following gene: 218698684

Centisome position: 5.88

GC content: 45.68

Gene sequence:

>243_bases
ATGCGCAAAATTACCTCAGTAAGCGTTGGCGAACAATTAGATAGTTTTATTACCCGGATGGTCCAGTCTGGTCGTTATGG
CTCGGCCAGTGAAGTGATGCGTTCAGCGCTTCGTCTATTGGAACAACAAGAATCCCGGGATGAAGCTGTCAGAAATGCAG
TTATTGAAGGTCTTGAGAGCGGTGAAAGTTCGATGACGCTTCGTGATATCGCAGCAGAAAGGAAGCAAAAACATCGTGTA
TAA

Upstream 100 bases:

>100_bases
TTTTTTTTCGATTGTTGATTAGTTTACTGAATACAGCTTTGGTTGTAGAAAGAGTTCTGACATATACTTTGTATTAATAG
TTAATACATGGAGATCGCTT

Downstream 100 bases:

>100_bases
GCTTAGCGGAAAAGCTGTTGAAGATTTCAGAGGGATCTATGACTACACGCTGGGAAAGTTTGGTGAGGAGCAGGCGGATC
GCTATACCGACTCTCTCGGC

Product: putative toxin antitoxin plasmid stabilisation system containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 80

Protein sequence:

>80_residues
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLESGESSMTLRDIAAERKQKHRV

Sequences:

>Translated_80_residues
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLESGESSMTLRDIAAERKQKHRV
>Mature_80_residues
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLESGESSMTLRDIAAERKQKHRV

Specific function: Unknown

COG id: COG3609

COG function: function code K; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0156 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y509_ECO57 (P58092)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A85537
- PIR:   E90686
- RefSeq:   NP_286149.1
- RefSeq:   NP_308488.1
- ProteinModelPortal:   P58092
- SMR:   P58092
- EnsemblBacteria:   EBESCT00000026076
- EnsemblBacteria:   EBESCT00000058007
- GeneID:   914563
- GeneID:   957365
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0509
- KEGG:   ecs:ECs0461
- GeneTree:   EBGT00050000009576
- HOGENOM:   HBG753338
- OMA:   GRYASTS
- ProtClustDB:   CLSK215823
- BioCyc:   ECOL83334:ECS0461-MONOMER
- InterPro:   IPR005360
- InterPro:   IPR010985
- InterPro:   IPR022789
- TIGRFAMs:   TIGR02606

Pfam domain/function: PF03693 RHH_2; SSF47598 Met_repress_like

EC number: NA

Molecular weight: Translated: 8997; Mature: 8997

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLES
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GESSMTLRDIAAERKQKHRV
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLES
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GESSMTLRDIAAERKQKHRV
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796