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The map label for this gene is sgrR

Identifier: 218698494

GI number: 218698494

Start: 87087

End: 88766

Strand: Reverse

Name: sgrR

Synonym: ECIAI39_0075

Alternate gene names: 218698494

Gene position: 88766-87087 (Counterclockwise)

Preceding gene: 218698495

Following gene: 218698492

Centisome position: 1.73

GC content: 55.3

Gene sequence:

>1680_bases
TTGCGCAGGAGTTCCCCTTTTATGCCATCTGCTCGTCTGCAACAACAGTTCATCCGCCTGTGGCAATGCTGCGAGGGTAA
ATCGCAGGACACGACGCTCAACGAACTGGCAGCGTTATTGAGCTGCTCGCGTCGTCATATGCGCACCCTGCTCAACACCA
TGCAGGATCGCGGCTGGCTGACGTGGGAAGCGGAAGTCGGGCGCGGTAAACGCTCGCGTCTGACATTCCTCTATACCGGG
CTGGCGCTTCAGCAACAGCGGGCGGAAGACCTGCTGGAGCAGGATCGTATCGATCAACTGGTGCAACTGGTTGGCGACAA
AGCGACTGTGCGGCAAATGCTGGTTTCTCATCTGGGCCGCAGCTTCCGCCAGGGGCGACACATCCTGCGTGTGCTCTACT
ATCGTCCGTTGCGTAATCTGCTACCTGGCAGCGCATTACGCCGTTCCGAAACCCATATCGCCCGGCAAATCTTCAGTTCG
CTAACGCGCATAAATGAGGAAAATGGGGAACTGGAAGCAGACATCGCCCACCACTGGCAGCAAATATCACCGCTTCACTG
GCGTTTCTTTTTGCGTCCAGGAGTCCATTTTCATCATGGTCGTGAACTGGAAATGGACGATGTGATCGCCTCTTTAAAAC
GGATCAATACGCTGCCGCTCTATTCGCATATTGCTGAAATTGTATCGCCGACGCCCTGGACGCTGGATATCCATCTCACG
CAACCGGACCGCTGGTTACCGTTACTGCTGGGGCAAGTTCCGGCGATGATCCTGCCGCGCGAATGGGAAACCCTCAGCAA
CTTTGCCAGCCATCCCATCGGCACCGGTCCGTATGCGGTGATCCGCAACAGCACCAATCAACTGAAAATTCAGGCATTCG
ATGACTTCTTCGGTTACCGGGCATTAATCGACGAAGTTAACGTCTGGGTTCTGCCGGAAATTGCCGACGAGCCAGCCGGA
GGGCTGATGCTAAAAGGGCCACAGGGCGAGGAAAAAGAGATTGAAAGCCGCCTGGAGGAAGGTTGCTACTATTTACTGTT
CGACAGCCGCACCCATCGCGGGACGAATCAGCAAGTCAGGGACTGGGTAAGCTATGTGCTTTCTCCAACTAATCTGGTCT
ATTTCGCTGAGGAACAGTACCAGCAACTGTGGTTCCCGGCTTATGGACTGCTCCCCCGTTGGCACCATGCTCGTCCGACA
CATTGCGAAAAACCCGCCGGGCTGGAAAGCCTCACCCTGACCTTTTATCAGGATCATATTGAGCATCGAGTGATTGCCGG
GATCATGCAGCAAATTCTGGCAAGTCACCAGGTCACGCTGGAAATCAAAGAGATCAGCTACGATCAGTGGCATGAAGGAG
AGATCGAGAGCGATATCTGGCTTAACAGCGCCAACTTTACGCTGCCGCTGGATTTTTCGCTGTTCGCGCACTTGTGCGAG
GTGCCGCTGCTCCAACGCTGTCTTCCGATCGACTGGCAAGCCGACGCCGCCCGCTGGCGCAATGGCGAAATGAACCTGGC
GAACTGGTGCCAGCAACTGGTCGCCAGCAAAGCAATGGTGCCACTTATCCACCACTGGCTGATCATTCAAGGGCAACGCA
GTATGCGCGGCCTGCGTATGAATACCCTCGGCTGGTTCGATTTTAAATCAGCGTGGTTTGCACCACCGGATCCAGAGTAG

Upstream 100 bases:

>100_bases
CGCGGTAAAATAGTGCTGATAAAACTGACGCATGGGGCACCTCCTTGCTTCATCGTTAGGAATTATTGACTTAATATAGG
GAAAATAAAATTGCTGACTT

Downstream 100 bases:

>100_bases
CTCGCGCCTTTTGGCGGTGATGAGCGCGTTTTTTATATTCAGACGGAATGAATAAAATACATTACTTTTATATTTTCTCT
GTTTTATGCATCGTCTGATT

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAG
GLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGTNQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPT
HCEKPAGLESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQRCLPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Sequences:

>Translated_559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAG
GLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGTNQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPT
HCEKPAGLESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQRCLPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>Mature_559_residues
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTG
LALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSS
LTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLT
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAG
GLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGTNQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPT
HCEKPAGLESLTLTFYQDHIEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
VPLLQRCLPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=551, Percent_Identity=97.459165154265, Blast_Score=1112, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=598, Percent_Identity=28.4280936454849, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 65080; Mature: 65080

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGR
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
QISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLT
HCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEC
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYR
CCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHH
ALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGTNQQVR
HHHHCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
DWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGLESLTLTFYQDHI
HHHHHHHCCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHH
VPLLQRCLPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRM
HHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEE
NTLGWFDFKSAWFAPPDPE
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRSSPFMPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGR
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHH
QISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIAEIVSPTPWTLDIHLT
HCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEC
QPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYR
CCCCHHHHHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHH
ALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGTNQQVR
HHHHCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
DWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARPTHCEKPAGLESLTLTFYQDHI
HHHHHHHCCCCEEEEEHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCE
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHH
VPLLQRCLPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRM
HHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEE
NTLGWFDFKSAWFAPPDPE
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]