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The map label for this gene is cadC

Identifier: 218697836

GI number: 218697836

Start: 4744647

End: 4746185

Strand: Reverse

Name: cadC

Synonym: EC55989_4626

Alternate gene names: 218697836

Gene position: 4746185-4744647 (Counterclockwise)

Preceding gene: 218697838

Following gene: 218697835

Centisome position: 92.07

GC content: 42.04

Gene sequence:

>1539_bases
ATGCAACAACCTGTAGTTCGCGTTGGCGAATGGCTTGTTACTCCGTCCATAAACCAAATTAGCCGCAATGGGCGTCAACT
TACCCTTGAGCCGAGATTAATCGATCTTCTGGTTTTCTTTGCTCAACACAGTGGCGAAGTACTTAGCAGGGATGAACTTA
TCGATAATGTCTGGAAGAGAAGTATTGTCACCAATCATGTTGTGACGCAGAGTATCTCAGAACTACGTAAGTCATTAAAA
GATAATGATGAAGATAGTCCTGTCTATATCGCTACTGTACCAAAGCGCGGCTATAAATTAATGGTGCCGGTTATCTGGTA
CAGCGAAGAAGAGGGAGAGGAAATAATGCTATCTTCGCCTCCCCCTATACCAGAGGCGGTTCCTGCCACAGATTCTCCCT
CCCACAGTCTTAACATTCAAAACACCGCAACGCCACCTGAACAATCCCCAGTTAAAAGCAAACGATTCACTACCTTTTGG
GTATGGTTTTTTTTCCTGTTGTCGTTAGGTATCTGTGTAGCACTGGTAGCGTTTTCAACTCTTGATACACGTCTTCCTAT
GAGCAAATCGCGTATTTTGCTCAATCCACGCGATATTGACATTAATATGGTAAATAAAAGTTGTAACAGCTGGAGTTCCC
CGTATCAGCTCTCTTACGCGATAGGCGTGGGTGATTTGGTGGCGACATCACTTAACACCTTCTCCACCTTTATGGTGCAT
GACAAAATCAACTACAACATTGATGAACCGAGCAGTTCCGGTAAAACATTATCTATTGCGTTTGTTAATCAGCGCCAATA
CCGTGCTCAACAATGCTTTATGTCGATAAAATTGGTAGACAATGCAGATGGTTCAACCATGCTGGATAAACGTTATGTCA
TCACTAACGGTAATCAGCTGGCGATTCAAAATGATTTACTGGAGAGTTTATCAAAAGCGTTAAACCAACCGTGGCCACAA
CGAATGCAGGAGACGCTCCAGCAAATATTGCCTCATCGCGGTGCGTTATTAACTAATTTTTATCAGGCACATGATTATTT
ACTGCATGGCGATGATAAATCATTGAATCGTGCCAGTGAATTATTAGGTGAGATTGTTCAATCATCCCCAGAATTTACCT
ACGCGAGAGCAGAAAAAGCATTAGTTGATATCGTGCGCCATTCTCAACATCCTTTAGATGAAAAACAATTAGCAGCACTG
AACACAGAAATAGACAACATTGTTACACTGCCGGAATTGAATAACCTGTCCATTATATATCAAATAAAAGCGGTCAGTGC
TCTGGTAAAAGGTAAAACAGATGAGTCTTACCAGGCGATAAATACTGGCATTGATCTTGAAATGTCCTGGCTAAATTATG
TGTTGCTTGGCAAGGTTTATGAAATGAAGGGGATGAACCGGGAAGCGGCTGATGCATATCTCACCGCCTTTAATTTACGC
CCAGGGGCAAACACCCTTTACTGGATTGAAAATGGTATATTCCAGACTTCTGTTCCTTATGTTGTACCTTATCTCGACAA
ATTTCTCGCTTCAGAATAA

Upstream 100 bases:

>100_bases
TGCATTCACCAATAATATGTAAATAAACCCATCTATAGATGGTAAAAATAGGTTGTGGCAATTATCATTGCATCATTCCC
TTTTCGAATGAGTTTCTATT

Downstream 100 bases:

>100_bases
GTAACTCCCGGGTTGATTTATGCTCGGGAATATTTGTTGTTGAGTTTTTGTATGTTTCTGTTGGTATAATATGTTGCGGC
AATTTATTTGCCGCATAATT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLK
DNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
VWFFFLLSLGICVALVAFSTLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQ
RMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAAL
NTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE

Sequences:

>Translated_512_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLK
DNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
VWFFFLLSLGICVALVAFSTLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQ
RMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAAL
NTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE
>Mature_512_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLK
DNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
VWFFFLLSLGICVALVAFSTLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQ
RMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAAL
NTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=512, Percent_Identity=99.609375, Blast_Score=1054, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 57828; Mature: 57828

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKR
CCCCHHHHCCEEECCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSP
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCEEEECCC
PPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFWVWFFFLLSLGICVALVAFST
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
HHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHEEEEEE
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQL
ECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCEEECCEEEEECCCEE
AIQNDLLESLSKALNQPWPQRMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASE
EEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCHHHHHHH
LLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAALNTEIDNIVTLPELNNLSIIY
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCCEEEEE
QIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
EHHHHHHHHCCCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECC
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE
CCCCEEEEEECCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKR
CCCCHHHHCCEEECCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSP
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCEEEECCC
PPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFWVWFFFLLSLGICVALVAFST
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
HHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHEEEEEE
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQL
ECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHEEEEEEECCCCCEEECCEEEEECCCEE
AIQNDLLESLSKALNQPWPQRMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASE
EEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCHHHHHHH
LLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAALNTEIDNIVTLPELNNLSIIY
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCCEEEEE
QIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
EHHHHHHHHCCCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECC
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE
CCCCEEEEEECCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]