Click here to switch to the map view.

The map label for this gene is yjcR

Identifier: 218697791

GI number: 218697791

Start: 4694398

End: 4695429

Strand: Reverse

Name: yjcR

Synonym: EC55989_4578

Alternate gene names: 218697791

Gene position: 4695429-4694398 (Counterclockwise)

Preceding gene: 218697792

Following gene: 218697790

Centisome position: 91.09

GC content: 56.01

Gene sequence:

>1032_bases
ATGGAAAGTACGCCGAAAAAAGCTCCTCGCAGTAAATTCCCTGCTCTGTTAGTGGTTGCGTTGGCGCTGGTTGCCCTTGT
TTTCGTTATCTGGCGCGTAGACAGTGCGCCATCAACTAATGACGCTTACGCGTCAGCAGATACCATTGATGTGGTGCCGG
AAGTCAGCGGTCGCATTGTAGAACTGGCGGTCACCGACAACCAGGCAGTCAAACAGGGCGATTTGCTGTTCCGCATTGAC
CCGCGCCCGTACGAAGCCAATCTGGCGAAAGCTGAAGCCTCCCTCGCGGCGCTGGATAAGCAAATTATGCTCACCCAGCG
TAGCGTTGATGCGCAACAGTTTGGTGCCGACTCGATTAATGCCACGGTAGAAAAAGCCCGTGCCGCCGCGAAACAGGCCA
CAGATACATTACGCCGCACCGAGCCATTACTGAAAGAGGGTTTTGTCTCAGCGGAAGACGTTGACCGTGCAAGAACTGCG
CAGCGCGCCGCAGAAGCCGATCTTAATGCCGTATTGTTACAGGCGCAGTCAGCCGCCAGCGCCGTCAGCGGCGTCGATGC
GCTGGTGGCGCAACGTGCGGCGGTCGAAGCGGATATTGCCCTGACCAAACTTCATCTGGAAATGGCGACCGTTCGCGCGC
CGTTTGATGGCCGGGTCATTTCCCTCAAAACCTCCGTCGGGCAATTTGCTTCTGCCATGCGCCCTATTTTTACCCTAATC
GACACTCGTCACTGGTACGTGATCGCCAACTTCCGCGAAACCGATCTGAAAAATATTCGCTCAGGTACACCCGCAACGAT
TCGCCTGATGAGTGACAGCGGCAAAACCTTCGAGGGTAAAGTGGATTCGATTGGCTACGGCGTGCTACCGGATGACGGCG
GCCTGGTGCTGGGCGGCCTGCCGAAAGTTTCTCGCTCTATTAACTGGGTCCGCGTTGCCCAGCGTTTTCCGGTCAAAATC
ATGGTCGATAAACCTGACCCGGAAATGTTCCGCATCGGCGCTTCGGCAGTCGCTAATCTTGAGCCGCAATAA

Upstream 100 bases:

>100_bases
TATCAATCTGGCATTTGTCGGAATTATTTATACCGCCCTTTTTGCTCTCTACGCCATGCTGTTCTGGCTGGCATTTTTCT
AATCTATTTGAGACGCGCTC

Downstream 100 bases:

>100_bases
TGAGCGCGCTCAACTCCCTGCCATTACCGGTGGTCAGGCTGCTGGCGTTCTTTCATGAAGAGTTAAGCGAGCGGCGACCA
GGCCGCGTGCCGCAGACCGT

Product: multidrug resistance protein MdtN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSINATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ

Sequences:

>Translated_343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSINATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ
>Mature_343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSINATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=343, Percent_Identity=99.7084548104956, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI87081951, Length=318, Percent_Identity=32.7044025157233, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789637, Length=337, Percent_Identity=28.7833827893175, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788711, Length=352, Percent_Identity=27.8409090909091, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789041, Length=333, Percent_Identity=29.1291291291291, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790012, Length=258, Percent_Identity=29.4573643410853, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790024, Length=254, Percent_Identity=27.1653543307087, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 36923; Mature: 36923

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIV
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCEE
ELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSIN
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
ATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEEHHHHHH
AVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHH
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGL
CCCEEEEEEECCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECC
PKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
HHHHHCCHHEEHHHHCCEEEEEECCCCHHEEECHHHHCCCCCC
>Mature Secondary Structure
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIV
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCEE
ELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSIN
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
ATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEEHHHHHH
AVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHH
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGL
CCCEEEEEEECCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECC
PKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
HHHHHCCHHEEHHHHCCEEEEEECCCCHHEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]