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The map label for this gene is aslB

Identifier: 218697515

GI number: 218697515

Start: 4363252

End: 4364487

Strand: Direct

Name: aslB

Synonym: EC55989_4270

Alternate gene names: 218697515

Gene position: 4363252-4364487 (Clockwise)

Preceding gene: 218697514

Following gene: 218697520

Centisome position: 84.64

GC content: 51.38

Gene sequence:

>1236_bases
ATGCTGCAACAGGTTCCAACGCGTGCTTTTCATGTGATGGCGAAACCGAGTGGTTCCGATTGTAATCTGAACTGTGACTA
CTGTTTTTATCTCGAAAAACAATCCCTTTACCGCGAAAAGCCAGTCACGCATATGGACGATGACACGCTGGAAGCGTATG
TCCGTCACTATATCGCTGCCAGCGAACCGCAAAACGAAGTGGCTTTTACCTGGCAGGGCGGCGAACCAACGTTACTCGGG
CTGGAGTTTTACCGCCGTGCCGTAAAGTTACAGGCGAAATACGGTGCTGGCAGGAAGATAAGTAACAGCTTCCAGACTAA
CGGCGTGCTGCTCGATGATAAATGGTGTGCATTTCTGGCAGAAAATCATTTTCTTGTTGGGTTATCGCTGGACGGTCCGG
CTGAGATCCACAATCAATATCGCGTGACCAAAGGTGGCAGACCAACGCATAAGCTGGTGATGCGTGCCCTGACGCTGCTG
CAAAAACATCATGTCGACTATAACGTGCTGGTCTGCGTCAACCGCACCAGCGCGCAGCAACCGTTGCAGGTTTATGATTT
TTTGTGCGATGCGGGAGTCGAATTCATCCAGTTTATTCCGGTGGTCGAGCGCCTGGCTGATGAAACAGCTGCCAGCGATG
GACTGAAACTACATGCGCCTGGTGATATTCAGGGGGAACTGACGGAATGGTCGGTGCGCCCCGATGAATTTGGTGAATTT
CTGGTGGCGATATTCAACCACTGGATCAAACGCGACGTCGGCAAGATTTTCGTGATGAATATCGAATGGGCGTTTGCCAA
TTTTGTCGGTGCGCCGGGTGCGGTTTGCCATCATCAGCCAACCTGTGGGCGCTCGGTGATTGTTGAGCACAACGGCGACG
TTTACGCCTGCGATCACTATGTTTATCCGCAATATCGGCTGGGGAATATGCATCAGCAAACAATTGCAGAAATGATCGAT
TCCCCGCAACAGCAGGTGTTTGGTGAAGATAAATTTAAGCAATTACCGGCGCAGTGTCGCAGTTGTAACGTGTTAAAAGC
GTGCTGGGGAGGCTGCCCGAAACACCGCTTCATGCTCGATGCCAGCGGCAAACCGGGGCTGAATTATTTGTGTGCCGGGT
ATCAGCGTTATTTCCGCCATCTACCGCCATATCTTAAAGCAATGGCTGATTTGCTGGCGCACGGTCGCCCGGCCAGTGAC
ATTATGCAGGCACATTTGCTGGTGGTGAATAAGTAA

Upstream 100 bases:

>100_bases
GTCACCCTCCCTTCGCAATAAACGCCCGTAATAACTCATTGCCCCACGGTATGATTTCGCCCTTAACGTATTGAAGGATG
ACTTCAGGCAAGGAGTGACC

Downstream 100 bases:

>100_bases
AAAAGCGGCCATTTTGTGGCCGCCTGCGGTTGATTGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACATGATCGTGCA
AATTCAATAAATTGCAGCGT

Product: regulator of arylsulfatase activity

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVKLQAKYGAGRKISNSFQTNGVLLDDKWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFNHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVNK

Sequences:

>Translated_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVKLQAKYGAGRKISNSFQTNGVLLDDKWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFNHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVNK
>Mature_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVKLQAKYGAGRKISNSFQTNGVLLDDKWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFNHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVNK

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=411, Percent_Identity=97.0802919708029, Blast_Score=842, Evalue=0.0,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=40.3061224489796, Blast_Score=328, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46511; Mature: 46511

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SEPQNEVAFTWQGGEPTLLGLEFYRRAVKLQAKYGAGRKISNSFQTNGVLLDDKWCAFLA
CCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHEE
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFNHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLLVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC
>Mature Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SEPQNEVAFTWQGGEPTLLGLEFYRRAVKLQAKYGAGRKISNSFQTNGVLLDDKWCAFLA
CCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHEE
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSAQQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAASDGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFNHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEECE
VYPQYRLGNMHQQTIAEMIDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLLVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]