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The map label for this gene is sgbH

Identifier: 218697298

GI number: 218697298

Start: 4119154

End: 4119816

Strand: Direct

Name: sgbH

Synonym: EC55989_4038

Alternate gene names: 218697298

Gene position: 4119154-4119816 (Clockwise)

Preceding gene: 218697297

Following gene: 218697299

Centisome position: 79.91

GC content: 58.82

Gene sequence:

>663_bases
ATGAGCCGACCACTTCTGCAACTGGCACTCGACCACTCATCACTTGAAGCCGCACAGCGCGACGTGACGCAGTTAAAAGA
CAGCGTCGATATTGTCGAAGCGGGCACCATTCTCTGTTTAAACGAAGGGCTTGGCGCGGTGAAAGCCTTGCGCGAACAGT
GCCCTGACAAAATCATCGTTGCCGACTGGAAGGTCGCCGACGCTGGTGAAACGCTCGCGCAACAGGCATTTGGCGCAGGC
GCTAACTGGATGACCATCATCTGCGCCGCACCGCTCGCGACGGTGGAAAAAGGCCACGCGATGGCGCAACGCTGCGGTGG
TGAAATTCAGATCGAGCTGTTCGGTAACTGGACGCTGGACGACGCCCGCGACTGGCATCGTATTGGCGTGCGGCAGGCGA
TTTATCATCGCGGTCGTGATGCACAGGCCAGCGGGCAACAGTGGGGCGAAGCCGATCTGGCACGCATGAAGGCGCTTTCC
GATATCGGCCTTGAGCTTTCCATTACCGGCGGGATTACCCCTGCTGACCTGCCGCTGTTTAAAGATATTCGCGTGAAAGC
GTTTATTGCCGGGCGAGCACTGGCAGGCTCAGCAAATCCGGCGCAGGTGGCTGGCGATTTCCATGCGCAAATCGACGCTA
TCTGGGGAGGCAAGCGTGCGTAA

Upstream 100 bases:

>100_bases
ATATGACCGCCCATCAGCTTTACCAACAAAAATACCAACGCTATCAGCATCTCATTGCCGCACTTCAGGGCTTTCACGCC
CGCATCAAGGAGCACATATT

Downstream 100 bases:

>100_bases
TCATCCGTTAGGGATTTATGAAAAGGCGCTGGCGAAAGATCTCTCCTGGCCGGAGCGGCTGGTGCTGGCAAAAAGCTGCG
GTTTTGATTTTGTCGAAATG

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGKRA

Sequences:

>Translated_220_residues
MSRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGKRA
>Mature_219_residues
SRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGA
NWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSD
IGLELSITGGITPADLPLFKDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGKRA

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=220, Percent_Identity=98.6363636363636, Blast_Score=435, Evalue=1e-124,
Organism=Escherichia coli, GI1790640, Length=216, Percent_Identity=44.9074074074074, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23533; Mature: 23402

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIV
CCCCHHHHHHCHHHHHHHHHHHHHHHHHHCEECCCEEEEECCCCHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
DARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSDIGLELSITGGITPADLPLF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
KDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGKRA
HHCEEEEEEECCEECCCCCHHHHCCCHHHEEEEECCCCCC
>Mature Secondary Structure 
SRPLLQLALDHSSLEAAQRDVTQLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIV
CCCHHHHHHCHHHHHHHHHHHHHHHHHHCEECCCEEEEECCCCHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMAQRCGGEIQIELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
DARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSDIGLELSITGGITPADLPLF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHH
KDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGKRA
HHCEEEEEEECCEECCCCCHHHHCCCHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 9274005; 11741871 [H]