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The map label for this gene is xylH

Identifier: 218697284

GI number: 218697284

Start: 4104296

End: 4105477

Strand: Direct

Name: xylH

Synonym: EC55989_4023

Alternate gene names: 218697284

Gene position: 4104296-4105477 (Clockwise)

Preceding gene: 218697283

Following gene: 218697285

Centisome position: 79.62

GC content: 53.98

Gene sequence:

>1182_bases
ATGTCGAAAAGCAATCCGTCTGAAGTGAAATTGGCCGTACCGACATCCGGTGGCTTTTCCGGGCTGAAATCACTGAATTT
GCAGGTCTTCGTGATGATTGCAGCTATCATCGCAATCATGCTGTTCTTTACCTGGACCACCGATGGTGCCTACTTAAGCG
CCCGTAACGTCTCCAACCTGTTACGCCAGACCGCGATTACCGGCATCCTCGCGGTAGGAATGGTGTTCGTCATAATTTCT
GCTGAAATCGACCTTTCCGTCGGCTCAATGATGGGGCTATTAGGTGGCGTCGCGGCGATTTGTGACGTCTGGTTAGGCTG
GCCTTTGCCACTTACCATCATTGTGACGTTGGTTCTGGGACTGCTTCTCGGTGCCTGGAACGGATGGTGGGTCGCGTACC
GCAAAGTCCCTTCATTTATTGTCACCCTCGCGGGCATGTTGGCATTTCGCGGCATACTCATTGGCATCACCAACGGCACG
ACTGTTTCCCCCACCAGCGCCGCGATGTCACAAATTGGGCAAAGCTATCTACCTGCCAGCACTGGCTTCATCATTGGCGC
GCTTGGCTTAATGGCTTTTGTTGGTTGGCAATGGCGCGGAAGAATGCGCCGTCAGGCTTTGGGTTTGCAGTCTCCGGCCT
CTACCGCAGTAGTCGGTCGCCAGGCTTTAACCGCTATCATCGTATTAGGCGCAATCTGGCTGTTGAATGATTACCGTGGC
GTTCCCACTCCTGTTCTGCTGCTGACGTTGCTGTTACTCGGCGGAATGTTTATGGCAACGCGGACGGCATTTGGACGACG
CATTTATGCCATCGGCGGCAATCTGGAAGCAGCACGTCTCTCCGGGATTAACGTTGAACGCACCAAACTTGCCGTGTTCG
CGATTAACGGATTAATGGTAGCCATCGCCGGATTAATCCTCAGTTCTCGACTTGGCGCTGGTTCACCTTCTGCGGAGAAT
ATCGCCGAGCTGGACGCAATTGCAGCATGCGTGATTGGCGGCACCAGCCTGGCTGGCGGTGTCGGGAGCGTGGCTGGAGC
GGTAATGGGGGCATTTATCATGGCTTCACTGGATAACGGCATGAGTATGATGGATGTACCGACCTTCTGGCAGTATATCG
TTAAAGGTGCGATTCTGTTGCTGGCAGTATGGATGGACTCCGCAACCAAACGCCGTTCTTGA

Upstream 100 bases:

>100_bases
CGGGTACTGGTGATGCATGAAGGGAAACTAAAAGCCAACCTGATAAATCATAACCTGACTCAGGAGCAGGTGATGGAAGC
CGCATTGAGGAGCGAACATC

Downstream 100 bases:

>100_bases
TTTTGATAAAAATTTTCTCGAAGCCGGTAACGTATTACCGGTTTTGAGTTTTTGCATGATTCAGCAGGAAAAGAACCATG
TTTACTAAACGTCACCGCAT

Product: D-xylose transporter subunit ; membrane component of ABC superfamily

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAEN
IAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS

Sequences:

>Translated_393_residues
MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAEN
IAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS
>Mature_392_residues
SKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISA
EIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTT
VSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRGV
PTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAENI
AELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=393, Percent_Identity=99.7455470737914, Blast_Score=756, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=359, Percent_Identity=35.6545961002786, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI145693152, Length=341, Percent_Identity=31.3782991202346, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788896, Length=161, Percent_Identity=39.7515527950311, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082395, Length=345, Percent_Identity=30.1449275362319, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787793, Length=345, Percent_Identity=30.7246376811594, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=38.8157894736842, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788471, Length=376, Percent_Identity=30.5851063829787, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787794, Length=157, Percent_Identity=30.5732484076433, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 41104; Mature: 40972

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNL
CCCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
LRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTTVSPTSAAMSQIGQSYLPAS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHCHHHCCCC
TGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMV
CCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCHHEEEEHHHHHHHH
AIAGLILSSRLGAGSPSAENIAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHCCC
MSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]