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The map label for this gene is argD

Identifier: 218697040

GI number: 218697040

Start: 3823492

End: 3824712

Strand: Reverse

Name: argD

Synonym: EC55989_3765

Alternate gene names: 218697040

Gene position: 3824712-3823492 (Counterclockwise)

Preceding gene: 218697041

Following gene: 218697036

Centisome position: 74.2

GC content: 54.63

Gene sequence:

>1221_bases
ATGGCAATTGAACAAACAGCAATTACACGGGCGACTTTCGATGAAGTGATCCTGCCGATTTATGCTCCGGCAGAGTTCAT
TCCGGTAAAAGGTCAGGGCAGCCGAATCTGGGATCAGCAAGGCAAGGAGTATGTCGATTTCGCGGGTGGCATTGCAGTTA
CGGCGTTGGGCCATTGCCATCCTGCGCTGGTGAATGCGTTAAAAACCCAGGGCGAAACTCTGTGGCATATCAGTAACGTT
TTCACCAATGAACCGGCGCTGCGTCTTGGGCGCAAACTGATTGAGGCGACGTTTGCCGAACGCGTGGTGTTTATGAACTC
CGGCACGGAAGCTAACGAAACCGCCTTTAAACTGGCACGCCATTATGCCTGTGTGCGTCATAGCCCGTTCAAAACCAAAA
TTATTGCCTTCCATAACGCTTTTCATGGTCGCTCGCTGTTTACCGTCTCGGTGGGCGGGCAGCCAAAATATTCCGACGGC
TTTGGGCCAAAACCGGCAGACATCATCCACGTTCCCTTTAACGATCTCCACGCAGTGAAAGCGGTGATGGATGATCACAC
CTGTGCGGTGGTGGTTGAGCCGATCCAGGGCGAGGGCGGTGTGACGGCTGCGACGCCAGAGTTTTTGCAGGGCTTGCGCG
AGCTGTGCGATCAACATCAGGCATTATTGGTGTTTGATGAAGTGCAGTGCGGGATGGGGCGGACTGGCGATTTGTTTGCT
TACATGCACTACGGTGTGACGCCGGATATTCTGACCTCTGCGAAAGCGTTAGGCGGCGGCTTCCCGATTAGCGCCATGCT
GACCACGGCGGAAATTGCTTCTGCGTTTCATCCTGGTTCTCACGGTTCCACCTACGGCGGTAATCCTCTGGCCTGTGCAG
TAGCGGGCGCGGCGTTTGATATCATCAATACCCCTGAAGTGCTGGAAGGCATTCAGGCGAAACGCCAGCGTTTTGTTGAC
CATTTGCAGAAGATCGATCAGCAGTACGATGTGTTTAGCGATATTCGCGGTATGGGGCTGTTGATTGGCGCGGAGCTTAA
GCCACAGTTCAAAGGTCGGGCGCGTGATTTCCTGTATGCGGGCGCAGAGGCTGGCGTAATGGTGCTGAATGCCGGACCGG
ATGTGATGCGTTTTGCACCGTCGCTGGTGGTGGAAGATGCGGATATCGATGAAGGGATGCAACGTTTCGCCCACGCGGTG
GCTAAGGTGATTGGGGCGTAA

Upstream 100 bases:

>100_bases
TTTCTGCATCGCTGATTTCTGATTGCCATTCAGTGATTTTTTATGCATATTTTGTGATTATAATTTCACATTTATTTATG
CGTAACAGGGTGATCATGAG

Downstream 100 bases:

>100_bases
ATACGAAGCATCAGGCAAAAGATGTCGGATGCGGCGTGAATGCCTTATCCGATGGTTTAGCCTGCATTACGCCTTCGAAT
CCCGCAACTTGCGACTCAGC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPQFKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAV
AKVIGA

Sequences:

>Translated_406_residues
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPQFKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAV
AKVIGA
>Mature_405_residues
AIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVF
TNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAY
MHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDH
LQKIDQQYDVFSDIRGMGLLIGAELKPQFKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAVA
KVIGA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=37.037037037037, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=38.7755102040816, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.9411764705882, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=30.9226932668329, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=31.283422459893, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=29.6758104738155, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=393, Percent_Identity=26.972010178117, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=99.5073891625616, Blast_Score=834, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=60.4591836734694, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=35.5932203389831, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=33.1683168316832, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI145693181, Length=330, Percent_Identity=36.6666666666667, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=31.8611987381703, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786991, Length=413, Percent_Identity=29.2978208232446, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=36, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=28.4064665127021, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=36.9230769230769, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=420, Percent_Identity=28.3333333333333, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=25.7471264367816, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=32.3170731707317, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=38.3838383838384, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.5062034739454, Blast_Score=216, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=29.6178343949045, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=435, Percent_Identity=24.5977011494253, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=35.0132625994695, Blast_Score=225, Evalue=3e-59,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=27.9342723004695, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=27.790973871734, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=30.166270783848, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=22.5581395348837, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=22.5581395348837, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=22.5581395348837, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43765; Mature: 43634

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPQFKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHEEE
GAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAVAKVIGA
CCCCCEEEEECCCHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPQFKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHEEE
GAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAVAKVIGA
CCCCCEEEEECCCHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]