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The map label for this gene is aapQ

Identifier: 218696969

GI number: 218696969

Start: 3769764

End: 3770945

Strand: Direct

Name: aapQ

Synonym: EC55989_3684

Alternate gene names: 218696969

Gene position: 3769764-3770945 (Clockwise)

Preceding gene: 218696968

Following gene: 218696970

Centisome position: 73.13

GC content: 50.17

Gene sequence:

>1182_bases
ATGTCTCATCGCCGCTCAACCGTTAAAGGCTCACTCTCTTTTGCCAACCCTACGGTTCGCGCCTGGTTATTCCAGATCCT
TGCCGTTGTTGCTGTTGTCGGCATTGTTGGTTGGTTATTTCACAACACTGTAACGAATCTCAATAATCGTGGCATTACTT
CAGGTTTTGCCTTTCTGGATCGCGGCGCTGGCTTCGGTATTGTCCAGCATTTGATCGATTACCAGCAGGGCGACACCTAC
GGACGCGTTTTTATTGTCGGCTTACTCAATACGCTACTGGTTTCTGCATTGTGTATTGTGTTCGCTTCTGTTTTAGGCTT
CTTTATCGGTCTGGCGAGACTTTCGGATAACTGGCTGCTACGAAAACTATCCACAATTTATATTGAGATCTTCCGTAATA
TTCCCCCGCTGCTGCAAATCTTCTTCTGGTACTTTGCCGTGTTGCGCAATTTGCCCGGACCACGCCAGGCTGTGAGCGCG
TTTGATCTGGCCTTTTTGAGCAATCGTGGGCTTTATATTCCGTCACCGCAGCTGGGAGACGGATTTATTGCGTTTATCCT
GGCTGTTGTTATGGCTATAGTCCTTTCTGTTGGGCTATTCCGCTTTAATAAAACATACCAGATAAAGACCGGACAACTGC
GCCGCACCTGGCCGATCGCCGCAGTGTTGATCATTGGTTTGCCTTTACTGGCGCAATGGCTTTTTGGCGCAGCACTACAC
TGGGATGTCCCAGCCCTACGAGGCTTTAACTTCCGCGGCGGGATGGTTTTAATTCCTGAACTGGCAGCCTTAACGCTGGC
ACTTTCGGTTTATACATCTGCATTTATCGCCGAGATTATCCGCGCTGGGATCCAGGCAGTGCCTTATGGTCAACATGAAG
CGGCTCGGTCACTGGGATTACCCAACCCGGTTACGCTACGCCAGGTCATTATTCCCCAGGCACTGCGAGTGATTATTCCG
CCGTTAACCAGCCAGTATCTCAACATCGTCAAAAACTCCTCTCTTGCCGCCGCTATTGGCTATCCCGATATGGTTTCGCT
GTTTGCTGGCACCGTGCTGAACCAGACGGGGCAAGCCATCGAGACGATAGCCATGACCATGTCGGTCTATCTGATTATCA
GCCTGACTATCTCGCTGCTGATGAATATCTATAACCGCCGCATCGCGATCGTTGAACGCTAA

Upstream 100 bases:

>100_bases
GGCGGTATTCAGTACGCGCCGCCCGTGCGTTAAGTCAGTGTGAGGTAACGGGCGTCGCTACGGCGGCGCTCTCTTCAGCG
TTATGCTTTCCGAGGTTTCT

Downstream 100 bases:

>100_bases
GGAGTCATGATGACAAAAGTATTGCTGTCTCAGCCCTCGCGCCCAGCGAGCCATAACTCAAGCCGCGCGATGGTGTGGGT
GCGAAAAAATCTGTTCTCCA

Product: amino-acid transporter subunit ; membrane component of ABC superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Sequences:

>Translated_393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
>Mature_392_residues
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYG
RVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAF
DLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALHW
DVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPP
LTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI48994930, Length=393, Percent_Identity=100, Blast_Score=778, Evalue=0.0,
Organism=Escherichia coli, GI1786874, Length=123, Percent_Identity=39.8373983739837, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788226, Length=171, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786873, Length=130, Percent_Identity=34.6153846153846, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082239, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787030, Length=134, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788645, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDX_ECOLI (P45767)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003809.1
- RefSeq:   YP_026209.1
- ProteinModelPortal:   P45767
- STRING:   P45767
- EnsemblBacteria:   EBESCT00000000645
- EnsemblBacteria:   EBESCT00000017119
- GeneID:   947765
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5544
- KEGG:   eco:b3269
- EchoBASE:   EB2684
- EcoGene:   EG12835
- eggNOG:   COG4597
- GeneTree:   EBGT00050000008885
- HOGENOM:   HBG704821
- OMA:   STIYIET
- ProtClustDB:   CLSK880631
- BioCyc:   EcoCyc:YHDX-MONOMER
- Genevestigator:   P45767
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 43262; Mature: 43131

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d02a40c)-; HASH(0x1d194e10)-; HASH(0x1d1a2fa8)-; HASH(0x182cd33c)-; HASH(0x1d1a452c)-; HASH(0x1cdf7c3c)-; HASH(0x1d19756c)-; HASH(0x1d19389c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEH
>Mature Secondary Structure 
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLNNRGITSGFAFLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAFDLAFLSNRGLYIPSPQLGD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCC
GFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGL
CCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
ETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503