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The map label for this gene is mreC

Identifier: 218696949

GI number: 218696949

Start: 3748504

End: 3749607

Strand: Reverse

Name: mreC

Synonym: EC55989_3663

Alternate gene names: 218696949

Gene position: 3749607-3748504 (Counterclockwise)

Preceding gene: 218696950

Following gene: 218696948

Centisome position: 72.74

GC content: 55.98

Gene sequence:

>1104_bases
ATGAAGCCAATTTTTAGCCGTGGCCCGTCGCTACAGATTCGCCTTATTCTGGCGGTGCTGGTGGCGCTCGGCATTATTAT
TGCCGACAGCCGCCTGGGGACGTTCAGTCAAATCCGTACTTATATGGATACCGCCGTCAGTCCTTTCTACTTTGTTTCCA
ATGCTCCTCGTGAATTGCTGGATGGCGTATCGCAGACGCTGGCCTCGCGTGACCAACTAGAACTTGAAAACCGGGCGTTA
CGTCAGGAACTGTTGCTGAAAAACAGTGAACTGCTGATGCTTGGACAATACAAACAGGAGAACGCGCGTCTGCGCGAGCT
GCTGGGTTCCCCGCTGCGTCAGGATGAGCAGAAAATGGTGACTCAGGTTATCTCCACGGTTAACGATCCTTATAGCGATC
AAGTTGTTATCGATAAAGGTAGCGTTAATGGCGTTTATGAAGGCCAGCCGGTCATCAGCGACAAAGGTGTTGTTGGTCAG
GTGGTGGCCGTCGCTAAACTGACCAGTCGCGTGCTGCTGATTTGTGATGCGACCCACGCGCTGCCAATCCAGGTGCTGCG
CAACGATATCCGCGTAATTGCAGCCGGTAACGGTTGTACGGATGATTTGCAGCTTGAGCATCTGCCAGCGAATACGGATA
TTCGTGTTGGTGATGTGCTGGTGACCTCCGGTCTGGGCGGTCGTTTCCCGGAAGGCTATCCGGTCGCGGTTGTCTCTTCC
GTAAAACTCGATACCCAGCGCGCTTATACTGTGATTCAGGCGCGTCCGACTGCAGGACTGCAACGTTTGCGTTATCTGCT
GCTGCTGTGGGGCGCGGATCGTAACGGCGCTAACCCGATGACGCCGGAAGAGGTGCATCGTGTTGCTAATGAACGTCTGA
TGCAGATGATGCCGCAGGTATTGCCTTCGCCAGACGCGATGGGGCCAAAGTTACCTGAACCGGCAACGGGGATCGCTCAG
CCGACTCCGCAGCAACCGACGACAGGAAATGCAGCTACTGCGCCTGCTGCGCCCACACAGCCTGCTGCTAATCGCTCTCC
ACAAAGGGCTACGCCGCCGCAAAGTGGTGCTCAACCGCCTGCGCGTGCGCCGGGAGGGCAATAG

Upstream 100 bases:

>100_bases
ACATGCACGGCGGCGACCTGTTCAGCGAAGAGTAATCGGATGCAGGCAGGGGAAATGTCTGTTTACCCTGCCTGGTCTGA
TACGAGAATACGCATAACTT

Downstream 100 bases:

>100_bases
TGGCGAGCTATCGTAGCCAGGGACGTTGGGTAATCTGGCTCTCTTTCCTCATTGCGCTGTTGCTGCAAATCATGCCCTGG
CCGGATAACCTGATTGTTTT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPTTGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ

Sequences:

>Translated_367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPTTGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ
>Mature_367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPTTGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=367, Percent_Identity=99.7275204359673, Blast_Score=735, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 39561; Mature: 39561

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHH
DGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
TQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQVVAVAKLTSRVLLICDATHA
HHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCH
LPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
HHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQV
EEECHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSPDAMGPKLPEPATGIAQPTPQQPTTGNAATAPAAPTQPAANRSPQRATPPQSGAQPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARAPGGQ
CCCCCCC
>Mature Secondary Structure
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHH
DGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
TQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQVVAVAKLTSRVLLICDATHA
HHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCH
LPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
HHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQV
EEECHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSPDAMGPKLPEPATGIAQPTPQQPTTGNAATAPAAPTQPAANRSPQRATPPQSGAQPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARAPGGQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2687239; 9278503; 3049542 [H]