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The map label for this gene is pdxK

Identifier: 218696054

GI number: 218696054

Start: 2767414

End: 2768265

Strand: Reverse

Name: pdxK

Synonym: EC55989_2708

Alternate gene names: 218696054

Gene position: 2768265-2767414 (Counterclockwise)

Preceding gene: 218696056

Following gene: 218696048

Centisome position: 53.7

GC content: 52.11

Gene sequence:

>852_bases
ATGAGTAGTTTGTTGTTGTTTAACGATAAGAGCAGGGCGCTGCAGGCGGATATCGTCGCCGTGCAGTCGCAGGTGGTTTA
CGGCAGCGTGGGCAACAGCATTGCCGTGCCTGCTATCAAACAGAACGGTCTGAATGTTTTTGCCGTGCCGACGGTATTGC
TGAGCAATACGCCGCATTATGACACTTTCTACGGTGGTGCGATTCCGGATGAATGGTTTAGCGGTTATTTGCGTGCGCTT
CATGAGCGTGATGCGCTGCGCCAGCTGCGCGCTGTAACCACGGGCTATATGGGAACGGCATCGCAAATCAAAATCCTTGC
CGAGTGGCTGACTGCGCTACGCAAAGACCATCCTGACCTATTGATCATGGTCGATCCGGTGATTGGCGATATTGATAGCG
GAATTTATGTCAAACCTGACCTTCCCGAGGCGTATCGACAATATTTACTGCCGCTGGCGCAGGGAATTACCCCCAATATC
TTTGAGCTGGAAATCCTGACCGGTAAAAATTGCCGCGATCTCGACAGTGCCATTGCTGCCGCAAAAAGTCTGCTTTCAGA
CACATTAAAATGGGTGGTGATTACCAGCGCCTCCGGTAATGAAGAAAATCAGGAGATGCAGGTGGTGGTGGTCAGTGCCG
ACAGCGTGAATGTCATTTCCCATTCACGGGTAAAAACCGACCTGAAAGGGACTGGCGACCTGTTTTGTGCTCAGCTTATC
AGTGGTTTGCTGAAAGGGAAGGCGTTAAACGATGCGGTGCACCGTTCGGGGTTGCGCGTACTGGAAGTGATGCGCTACAC
CCAGCAGCATGAGAGCGATGAATTGATTTTGCCGCCGCTGGCGGAAGCATAA

Upstream 100 bases:

>100_bases
TTACCTTATCCTTGTTTTGTGATAGCCGATTTGACTGCCAGAATCAGGTAAAGTTTCGGTTGGAATACGATGAGGATCAT
CGGCAAGGAGAAAAAATTAA

Downstream 100 bases:

>100_bases
AAAATGGCGCCGATGGGCGCCATTTTTCACTGCGGCAAGAATTACTTCTTGATGCGGATAACCGGGGTTTCACCCACGGT
TACGCTACCGGACAGTTTGA

Product: pyridoxal kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRAL
HERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLI
SGLLKGKALNDAVHRSGLRVLEVMRYTQQHESDELILPPLAEA

Sequences:

>Translated_283_residues
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRAL
HERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLI
SGLLKGKALNDAVHRSGLRVLEVMRYTQQHESDELILPPLAEA
>Mature_282_residues
SSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALH
ERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIF
ELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLIS
GLLKGKALNDAVHRSGLRVLEVMRYTQQHESDELILPPLAEA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=244, Percent_Identity=29.0983606557377, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788758, Length=283, Percent_Identity=98.2332155477032, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1787924, Length=266, Percent_Identity=28.9473684210526, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17507759, Length=271, Percent_Identity=29.8892988929889, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17507757, Length=281, Percent_Identity=28.8256227758007, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320806, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324354, Length=239, Percent_Identity=27.6150627615063, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45553007, Length=188, Percent_Identity=34.0425531914894, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 30886; Mature: 30755

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHY
CCCEEEECCCCHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCEEEEECHHEECCCCCC
DTFYGGAIPDEWFSGYLRALHERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCE
LIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAA
EEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
AKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLI
HHHHHHHCEEEEEEECCCCCCCCCEEEEEEEECCCEEEHHHHHHHCCCCCCHHHHHHHHH
SGLLKGKALNDAVHRSGLRVLEVMRYTQQHESDELILPPLAEA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure 
SSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHY
CCEEEECCCCHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCEEEEECHHEECCCCCC
DTFYGGAIPDEWFSGYLRALHERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCE
LIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAA
EEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHH
AKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLI
HHHHHHHCEEEEEEECCCCCCCCCEEEEEEEECCCEEEHHHHHHHCCCCCCHHHHHHHHH
SGLLKGKALNDAVHRSGLRVLEVMRYTQQHESDELILPPLAEA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA