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The map label for this gene is cld

Identifier: 218695653

GI number: 218695653

Start: 2328350

End: 2329330

Strand: Reverse

Name: cld

Synonym: EC55989_2286

Alternate gene names: 218695653

Gene position: 2329330-2328350 (Counterclockwise)

Preceding gene: 218695654

Following gene: 218695643

Centisome position: 45.19

GC content: 47.6

Gene sequence:

>981_bases
ATGATGAGAGTAGAAAATAATAATGTTTCTGGGCAAAACCATGACCCGGAACAGATTGATTTGATTGATTTACTGGTGCA
GTTGTGGCGCGGCAAGATGACAATTATCATCTCTGTCATTGTGGCTATTGCCTTGGCTATAGGGTATCTGGCCGTTGCCA
AAGAAAAGTGGACTTCCACAGCTATCGTTACTCAACCTGATGTGGGGCAAATCGCTGGTTATACCAACGCGATGAATGTG
ATTTACGGTCCGGCTGTACCGAAAGTCTCCGACATTCAGGCTTCACTTATCGGACGTTACAGTACTGCATTCTCAGCATT
AGCGGAAACGCTGGATAACCAGGAAGAAGCAGAAAAGCTGACCATTGAGCCTACCGTTAAAAACCAGTCGTTACCATTGG
CGGTGTCTTATGTTGGTGAAACACCTGAAGGTGCGCAGAAGCAGCTGGCGAAGTATATCCAGCAAGTTGACGACCAGGTA
AATGAAGAACTGGAAAAAGACCTGAAAGACAACATCGCGCTGCAAATGAAAAACTTGCAGGATTCTCTGAAGACCCAGGA
AGTGGTTGCGCAGGAGCAGAAAGATCTGCGTATCCGTCAGATTCAGGAAGCGTTGCAGTATGCGAATCAGGCGCAGGTGA
CAAAGCCACAGGTTCAGCAGACTGAAGATGTGACGCAAGATACGTTGTTCCTTTTGGGGAGCGAAGCGCTGGAGTCGATG
ATTAAGCACGAGGCGACCCGTCCGTTGGTGTTCTCGCCAAACTACTATCAGACTCGTCAAAACCTGTTGGATATTGAAAA
CTTAAAGGTTGATGATCTTGATATTCATGCTTACCGCTATGTGATGAAACCGACGTTACCTATTCGTCGCGATAGTCCGA
AAAAGGCAATCACCTTGATTCTGGCGGTGCTGCTGGGTGGCATGGTTGGCGCGGGGATTGTGCTGGGGCGTAATGCTCTG
CGTAATTACAACGCGAAATAA

Upstream 100 bases:

>100_bases
CCCTTTGTAATAATTCATTATTTTTATCATTTATCCTATAGCATTCATGGCGATTATCGCTAAACTATGGCGACTTAAAA
TTATTTCGTCCGTTAGGGTA

Downstream 100 bases:

>100_bases
TCTTTGCAGCTTTAAAGAAAACGGGCAGGGTGGTGACACCTTGCCCGTTTTTTTTTGCCGGATGCGACAACAACATCGCA
TCCGCTTACCCCGCAACTCA

Product: regulator of length of O-antigen component of lipopolysaccharide chains

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNV
IYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQV
NEELEKDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESM
IKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK

Sequences:

>Translated_326_residues
MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNV
IYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQV
NEELEKDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESM
IKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK
>Mature_326_residues
MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNV
IYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQV
NEELEKDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESM
IKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111/M92) and o

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=91.4110429447853, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI87082332, Length=332, Percent_Identity=25.6024096385542, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786802, Length=345, Percent_Identity=27.536231884058, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 36327; Mature: 36327

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTST
CCEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AIVTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKL
EEEECCCHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
TIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQVNEELEKDLKDNIALQMKNLQ
EECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLI
HHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
LAVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTST
CCEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AIVTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKL
EEEECCCHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
TIEPTVKNQSLPLAVSYVGETPEGAQKQLAKYIQQVDDQVNEELEKDLKDNIALQMKNLQ
EECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLI
HHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
LAVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]