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The map label for this gene is nlpC

Identifier: 218695270

GI number: 218695270

Start: 1940899

End: 1941363

Strand: Reverse

Name: nlpC

Synonym: EC55989_1876

Alternate gene names: 218695270

Gene position: 1941363-1940899 (Counterclockwise)

Preceding gene: 218695271

Following gene: 218695269

Centisome position: 37.66

GC content: 49.25

Gene sequence:

>465_bases
ATGCGTTTCTGCCTTATTTTGATCACAGCACTGCTTCTGGCCGGGTGTAGCCACCATAAAGCACCGCCGCCAAATGCCAG
ACTTTCTGATTCGATTACCGTTATTGCCGGTTTGAACGACCAGCTACAAAGCTGGCATGGCACGCCGTATCGTTATGGTG
GCATGACGCGGCGCGGTGTGGACTGTTCGGGATTTGTGGTTGTGACGATGCGCGATCGTTTCGATTTGCAGCTGCCCCGT
GAAACCAAACAACAAGCCTCTATTGGCACGCAAATTGATAAAGACGAGTTGCTGCCAGGTGACCTGGTCTTTTTCAAAAC
GGGTTCCGGACAAAATGGTTTGCATGTAGGTATTTACGATACCAACAACCAATTTATCCACGCCTCTACCAGCAAGGGAG
TGATGCGTTCCTCACTTGATAATGTCTATTGGCAGAAAAATTTCTGGCAGGCGAGACGAATTTAG

Upstream 100 bases:

>100_bases
GAATGCTGATTTCGACCATCTGATTTCATTAGTATCTTGAAAATCGGGTAATTACGACGCTAAATTAATGCAAGAATAAA
AAACAGAGGAACCGTACGGA

Downstream 100 bases:

>100_bases
TATGTCGAAAAATGGACGGCGATGATACATCGCCGTCCATTTACTCCTGAATACAGTAGTATTTTGCAGACAAAAATTCC
GTAAATGGATTATTCGTTTA

Product: putative peptidase lipoprotein

Products: NA

Alternate protein names: ORF-17

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPR
ETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI

Sequences:

>Translated_154_residues
MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPR
ETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI
>Mature_154_residues
MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPR
ETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI

Specific function: Unknown

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpC/p60 family

Homologues:

Organism=Escherichia coli, GI1788001, Length=154, Percent_Identity=100, Blast_Score=323, Evalue=3e-90,
Organism=Escherichia coli, GI1788501, Length=127, Percent_Identity=48.0314960629921, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1787944, Length=119, Percent_Identity=36.1344537815126, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1786421, Length=119, Percent_Identity=34.453781512605, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NLPC_ECOLI (P23898)

Other databases:

- EMBL:   M14031
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D64929
- RefSeq:   AP_002328.1
- RefSeq:   NP_416223.1
- ProteinModelPortal:   P23898
- SMR:   P23898
- STRING:   P23898
- MEROPS:   C40.004
- EnsemblBacteria:   EBESCT00000004627
- EnsemblBacteria:   EBESCT00000015308
- GeneID:   946220
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1698
- KEGG:   eco:b1708
- EchoBASE:   EB1123
- EcoGene:   EG11133
- eggNOG:   COG0791
- GeneTree:   EBGT00050000009578
- HOGENOM:   HBG362075
- OMA:   WKARYIG
- ProtClustDB:   CLSK880170
- BioCyc:   EcoCyc:EG11133-MONOMER
- Genevestigator:   P23898
- InterPro:   IPR000064

Pfam domain/function: PF00877 NLPC_P60

EC number: NA

Molecular weight: Translated: 17283; Mature: 17283

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCEECCCCCCCCC
DCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYD
CCCCEEEEEEECCCCEECCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEE
TNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI
CCCEEEEECCCCCHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCEECCCCCCCCC
DCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYD
CCCCEEEEEEECCCCEECCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEE
TNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI
CCCEEEEECCCCCHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503