| Definition | Escherichia coli 55989, complete genome. |
|---|---|
| Accession | NC_011748 |
| Length | 5,154,862 |
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The map label for this gene is aroH
Identifier: 218695266
GI number: 218695266
Start: 1937067
End: 1938113
Strand: Direct
Name: aroH
Synonym: EC55989_1872
Alternate gene names: 218695266
Gene position: 1937067-1938113 (Clockwise)
Preceding gene: 218695265
Following gene: 218695267
Centisome position: 37.58
GC content: 53.01
Gene sequence:
>1047_bases ATGAACAGAACTGACGAACTCCGTACTGCGCGTATTGAGAGCCTGGTAACGCCCGCCGAACTCGCGCTACGGTATCCCGT AACGCCTGGCGTCGCCACCCATGTCACCGACTCCCGCCGCAGAAATGAAAAAATACTGAATGGTGAAGATAAGCGACTGT TGGTTATTATTGGCCCCTGCTCGATCCACGATCTCACCGCTGCAATGGAGTACGCCACCCGTCTGCAGTCGCTGCGCAAC CAGTACCAGTCACGGCTGGAAATCGTAATGCGCACCTATTTTGAAAAACCACGAACTGTTGTCGGCTGGAAAGGGCTAAT CTCCGATCCGGATTTAAACGGCAGCTATCGGGTAAATCACGGTCTGGAGCTGGCGCGCAAATTACTTTTACAGGTAAATG AGCTGGGTGTCCCTACCGCGACTGAGTTCCTCGATATGGTGACCGGTCAGTTTATTGCTGATTTAATCAGTTGGGGCGCG ATTGGCGCACGTACTACCGAAAGTCAGATCCACCGTGAAATGGCTTCGGCACTCTCCTGTCCGGTAGGTTTTAAAAATGG TACCGATGGCAACACGCGGATTGCCGTGGATGCTATCCGCGCAGCCCGCGCCAGCCATATGTTTCTCTCGCCAGACAAAA ATGGTCAGATGACCATCTATCAGACCAGCGGCAACCCGTATGGCCACATTATTATGCGTGGCGGCAAAAAACCGAATTAT CATGCCGATGATATCGCCGCAGCCTGCGATACGCTGCACGAGTTTGATTTACCTGAACATCTGGTGGTGGATTTCAGCCA CGGTAACTGCCAGAAGCAGCACCGTCGCCAGTTAGAAGTTTGTGAGGATATTTGTCAGCAAATCCGCAATGGCTCTACGG CGATTGCTGGAATTATGGCGGAAAGTTTCCTGCGCGAAGGAACGCAAAAAATCGTCGGCGGTCAGCCGCTCACTTACGGT CAATCCATTACCGACCCGTGTCTGGGCTGGGAAGATACCGAACGCCTGGTCGAAAAACTCGCCTCTGCGGTAGATACCCG CTTCTGA
Upstream 100 bases:
>100_bases GACACACCTCGCACTTGAAATCAGCTGCGATTGGTTTATCGTGATGCGCATCACTTCCCGGTAGTCCTGCCGTAGAAGCA ACAAATTTCTGAGACTTGTA
Downstream 100 bases:
>100_bases ATGCGTGCCCATTCCTGATGGGATGGGCATTTCTGCGCAACTTGTTGTCTTTTCAACACATTACTGCTTGCTCTGGCCTG CCATAATATTGATAATAAGA
Product: phospho-2-dehydro-3-deoxyheptonate aldolase
Products: NA
Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]
Number of amino acids: Translated: 348; Mature: 348
Protein sequence:
>348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRNEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF
Sequences:
>Translated_348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRNEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF >Mature_348_residues MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRNEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG QSITDPCLGWEDTERLVEKLASAVDTRF
Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]
COG id: COG0722
COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I DAHP synthase family [H]
Homologues:
Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=99.4252873563218, Blast_Score=723, Evalue=0.0, Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=56.8115942028986, Blast_Score=421, Evalue=1e-119, Organism=Escherichia coli, GI1788953, Length=329, Percent_Identity=49.2401215805471, Blast_Score=333, Evalue=1e-92, Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=48.9971346704871, Blast_Score=337, Evalue=1e-93, Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=42.7762039660057, Blast_Score=292, Evalue=7e-80,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR006218 - InterPro: IPR006219 [H]
Pfam domain/function: PF00793 DAHP_synth_1 [H]
EC number: =2.5.1.54 [H]
Molecular weight: Translated: 38707; Mature: 38707
Theoretical pI: Translated: 6.90; Mature: 6.90
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRNEKILNGEDKRLLVIIGPC CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHCCCHHHHCCCCCCCCCCEEEEEECCC SIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRNEKILNGEDKRLLVIIGPC CCCCHHHHHHHHHHHCCHHHHHEECCCCCCCHHHCCCHHHHCCCCCCCCCCEEEEEECCC SIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH GLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC PVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY CCCCCCCCCCCCEEHHHHHHHHHHCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMA CHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH ESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]